Results 91 to 100 of about 92,409 (330)

The Milky Way and other spiral galaxies

open access: yesEPJ Web of Conferences, 2012
Cosmologists have often considered the Milky Way as a typical spiral galaxy, and its properties have considerably influenced the current scheme of galaxy formation.
Wang J.L.   +5 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Estimating the Initial Mass of the Gaia–Enceladus Dwarf Galaxy with a Chemical Evolution Model

open access: yesThe Astrophysical Journal
This work investigates the initial mass and chemical evolution history of the Gaia–Enceladus dwarf galaxy. We combine spectroscopic data from APOGEE with astrometric data from Gaia Data Release 3 to identify Gaia–Enceladus candidate stars via a machine ...
Olcay Plevne, Furkan Akbaba
doaj   +1 more source

Star Formation in the Central Molecular Zone of the Milky Way [PDF]

open access: green, 2022
Jonathan D. Henshaw   +5 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Infall Times for Milky Way Satellites From Their Present-Day Kinematics

open access: yes, 2011
We analyze subhalos in the Via Lactea II (VL2) cosmological simulation to look for correlations among their infall times and z = 0 dynamical properties.
Abramson   +146 more
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

The Extremely Metal-rich Knot of Stars at the Heart of the Galaxy

open access: yesThe Astrophysical Journal
We show with Gaia XP spectroscopy that extremely metal-rich (EMR) stars in the Milky Way ([M/H] _XP ≳ 0.5) are largely confined to a tight “knot” at the center of the Galaxy. This EMR knot is round in projection, has a fairly abrupt edge near R _GC,proj ∼
Hans-Walter Rix   +17 more
doaj   +1 more source

Molecular gas and star formation in the Milky Way

open access: yesEPJ Web of Conferences, 2012
The dense molecular gas is the ideal tracer of the spiral structure in the Milky Way, and should be used intensively to solve the puzzle of its structure. In spite of our position inside the plane, we can hope to disentangle the structures, with position-
Combes F.
doaj   +1 more source

Spitzer IRAC Observations of Star Formation in N159 in the LMC

open access: yes, 2004
We present observations of the giant HII region complex N159 in the LMC using IRAC on the {\it Spitzer Space Telescope}. One of the two objects previously identified as protostars in N159 has an SED consistent with classification as a Class I young ...
Bessell M. S.   +22 more
core   +2 more sources

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