Results 91 to 100 of about 90,260 (324)

Spitzer IRAC Observations of Star Formation in N159 in the LMC

, 2004
We present observations of the giant HII region complex N159 in the LMC using IRAC on the {\it Spitzer Space Telescope}. One of the two objects previously identified as protostars in N159 has an SED consistent with classification as a Class I young ...
Bessell M. S., Caswell J. L., Charles E. Woodward, Clarke J. N., Comeron F., Deharveng L., Deharveng L., Elisha Polomski, Gatley I., Gatley I., Heydari-Malayeri M., Heydari-Malayeri M., Hunt M. R., Johansson L. E. B., Jones T. J., Lightfoot J. F., Martha L. Boyer, McGee R. X., Meynet G., Robert D. Gehrz, Sievers A. W., Terry J. Jones, Werner M. W.   +22 more
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

The Parallax and 3D Kinematics of Water Masers in the Massive Star-forming Region G034.43+0.24

The Astrophysical Journal, 2023
We report a measurement of the trigonometric parallax of 22 GHz water masers in the massive star-forming region G034.43+0.24 as part of the Bar and Spiral Structure Legacy Survey using the Very Long Baseline Array.
Xiaofeng Mai, Bo Zhang, M. J. Reid, L. Moscadelli, Shuangjing Xu, Yan Sun, Jingdong Zhang, Wen Chen, Shiming Wen, Qiuyi Luo, Karl M. Menten, Xingwu Zheng, Andreas Brunthaler, Ye Xu, Guangli Wang   +14 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

The Milky Way and other spiral galaxies

EPJ Web of Conferences, 2012
Cosmologists have often considered the Milky Way as a typical spiral galaxy, and its properties have considerably influenced the current scheme of galaxy formation.
Wang J.L., Yang Y.B., Flores H., Puech M., Hammer F., Fouquet S.   +5 more
doaj   +1 more source

The Star Formation History of the Milky Way’s Nuclear Star Cluster

The Astrophysical Journal, 2023
We report the first star formation history study of the Milky Ways nuclear star cluster (NSC), which includes observational constraints from a large sample of stellar metallicity measurements.
Zhuo Chen, Tuan Do, Andrea M. Ghez, Matthew W. Hosek Jr., Anja Feldmeier-Krause, Devin S. Chu, Rory O. Bentley, Jessica R. Lu, Mark R. Morris   +8 more
doaj   +1 more source

Dissipationless Formation and Evolution of the Milky Way Nuclear Star Cluster

, 2012
Abridged: In one widely discussed model for the formation of nuclear star clusters (NSCs), massive globular clusters spiral into the center of a galaxy and merge to form the nucleus. It is now known that at least some NSCs coexist with supermassive black
Agarwal, Alessandra Mastrobuono-Battisti, Antonini, Bartko, Bekki, Böker, Carollo, Charbonnel, Côté, David Merritt, Do, Ebisuzaki, Emsellem, Fabio Antonini, Ferrarese, Figer, Figer, Gebhardt, Genzel, Ghez, Gillessen, Gualandris, Hashimoto, Haşegan, Ibata, Jordán, Lauer, Loose, Lotz, Makino, Matthews, Merritt, Merritt, Merritt, Meynet, Milosavljević, Miocchi, Murali, Ostriker, Pesce, Pfuhl, Poon, Portegies Zwart, Roberto Capuzzo-Dolcetta, Rosenberg, Saha, Schaerer, Schaerer, Schaller, Schinnerer, Schinnerer, Schödel, Schödel, Seth, Seth, Sjouwerman, Spitzer, Takahashi, Wehner, Zhao   +59 more
core   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source