Results 51 to 60 of about 5,633 (170)

Organic Light‐Emitting Diode in Phototherapy Applications

Advanced Photonics Research, Volume 7, Issue 2, February 2026.
This article systematically reviews the development of organic light‐emitting diodes (OLEDs) in phototherapy, constructs a technical framework, and establishes a multidimensional knowledge graph encompassing indications, wavelengths, and light intensity.
Yingguang Zhu, Yonglan Hu, Yingjie Cui, Lixue Guo, Guohui Zhang, Haixia Qiu, Defu Chen, Changyong Pan, Huijuan Yin, Suling Zhao   +9 more
wiley   +1 more source

Severe post-kala-azar dermal leishmaniasis successfully treated with miltefosine in an Ethiopian HIV patient

International Journal of Infectious Diseases, 2019
Post-kala-azar dermal leishmaniasis (PKDL) is a neglected tropical disease characterized by a dermatosis which often appears after successful treatment of visceral leishmaniasis caused by Leishmania donovani.
Charles Abongomera, Tullia Battaglioli, Cherinet Adera, Koert Ritmeijer   +3 more
doaj   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

Nano Select, Volume 7, Issue 2, February 2026.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri, Dominique de Jong‐Hoogland, Martin B. Ulmschneider   +2 more
wiley   +1 more source

Miltefosine induces metacaspase and PARP genes expression in Leishmania infantum

Brazilian Journal of Infectious Diseases
OBJECTIVES: Apoptosis is the process of programmed cell death (PCD) that occurs in both animal and plant cells. Protozoan parasites possess metacaspase and these caspase-related proteases could be involved in the PCD pathways in these organisms ...
Shahram Khademvatan, Mohammad Javad Gharavi, Jasem Saki   +2 more
doaj   +1 more source

Miltefosine induces metacaspase and PARP genes expression in Leishmania infantum

Brazilian Journal of Infectious Diseases, 2011
Objectives: Apoptosis is the process of programmed cell death (PCD) that occurs in both animal and plant cells. Protozoan parasites possess metacaspase and these caspase-related proteases could be involved in the PCD pathways in these organisms ...
Shahram Khademvatan, Mohammad Javad Gharavi, Jasem Saki   +2 more
doaj   +1 more source

Unveiling the Leishmanicidal Mechanism of 4‐Nerolidylcatechol Isolated From Piper peltatum Against Leishmania infantum

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The present study assessed the leishmanicidal activity of 4‐nerolidylcatechol (4‐NC) (1) isolated from Piper peltatum leaves against promastigotes and amastigotes of Leishmania amazonensis, L. braziliensis, and L. infantum. The plant was fractionated, leading to the isolation and chemical identification of 4‐NC (1). Biochemical techniques were
Fabiana Brusco Lorenzetti, Rodolfo Bento Balbinot, Danielle Lazarin‐Bidóia, Viviane dos Santos Faiões, Eduardo Caio Torres‐Santos, Celso Vataru Nakamura, Tânia Ueda‐Nakamura, Diógenes Aparício Garcia Cortez, Benedito Prado Dias Filho   +8 more
wiley   +1 more source

Miltefosine reinvigorates exhausted T cells by targeting their bioenergetic state

Cell Reports Medicine
Summary: T cell exhaustion presents a major challenge for the efficacy of both immune checkpoint inhibitors (ICBs) and chimeric antigen receptor T (CAR-T) cell immunotherapies.
Xingying Zhang, Chenze Zhang, Shan Lu, Jingxi Dong, Na Tang, Yao Wang, Weidong Han, Xi Pan, Xiang Zhang, Duan Liu, Ng Shyh-Chang, Yu Wang, Guihai Feng, Haoyi Wang   +13 more
doaj   +1 more source

Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids

Lipids in Health and Disease, 2010
The alkylphospholipid analog miltefosine (hexadecylphosphocholine) is a membrane-directed antitumoral and antileishmanial drug belonging to the alkylphosphocholines, a group of synthetic antiproliferative agents that are promising candidates in ...
Segovia Josefa L, Marco Carmen, Ríos-Marco Pablo, Jiménez-López José M, Carrasco María P   +4 more
doaj   +1 more source

Inefficacy of the association N-methyl glucamine and topical miltefosine in the treatment of experimental cutaneous leishmaniasis by Leishmania (Leishmania) amazonensis

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
Pentavalent antimonial (SbV) is the first treatment for cutaneous leishmaniasis (CL). Other drugs present similar side effects and higher cost. Oral miltefosine is effective to treat kala-azar.
R. N. R. Sampaio, I. C. Lucas, H. L. Takami   +2 more
doaj   +1 more source

Advanced case of PKDL due to delayed treatment: A rare case report.

PLoS Neglected Tropical Diseases, 2020
Post-kala-azar dermal leishmaniasis (PKDL) is clinical outcome of visceral leishmaniasis (VL) and is thought to be the potential reservoir of parasite. Miltefosine (MF) is the only oral drug existing for treatment of post-kala-azar dermal leishmaniasis ...
Roshan Kamal Topno, Vidya Nand Rabi Das, Maneesh Kumar, Major Madhukar, Krishna Pandey, Neena Verma, Kanhaiya Agrawal, Chandra Shekhar Lal, Niyamat Ali Siddiqui, Sanjiva Bimal, Pradeep Das   +10 more
doaj   +1 more source