Results 61 to 70 of about 10,985 (213)

Organic Light‐Emitting Diode in Phototherapy Applications

Advanced Photonics Research, Volume 7, Issue 2, February 2026.
This article systematically reviews the development of organic light‐emitting diodes (OLEDs) in phototherapy, constructs a technical framework, and establishes a multidimensional knowledge graph encompassing indications, wavelengths, and light intensity.
Yingguang Zhu, Yonglan Hu, Yingjie Cui, Lixue Guo, Guohui Zhang, Haixia Qiu, Defu Chen, Changyong Pan, Huijuan Yin, Suling Zhao   +9 more
wiley   +1 more source

Ascorbic acid reduces the genetic damage caused by miltefosine (hexadecylphosphocholine) in animals infected by Leishmania (Leishamnia) infantum without decreasing its antileishmanial activity

International Journal for Parasitology: Drugs and Drug Resistance, 2019
Leishamaniasis is a neglected disease caused by over 20 Leishmania species, occurring in more than a hundred countries. Miltefosine (hexadecylphosphocholine) is the single oral drug used in treatment for leshmaniases, including cases of infections ...
Patrícia Valéria Castelo-Branco, Hugo José Alves, Raissa Lacerda Pontes, Vera Lucia Maciel-Silva, Silma Regina Ferreira Pereira   +4 more
doaj   +1 more source

Combination of liposomal CpG oligodeoxynucleotide 2006 and miltefosine induces strong cell-mediated immunity during experimental visceral leishmaniasis. [PDF]

PLoS ONE, 2014
Immuno-modulators in combination with antileishmanial drug miltefosine is a better therapeutic approach for treatment of Visceral Leishmaniasis (VL) as it not only reduces the dose of miltefosine but also shortens the treatment regimen.
Rahul Shivahare, Preeti Vishwakarma, Naveen Parmar, Pawan Kumar Yadav, Wahajul Haq, Mrigank Srivastava, Suman Gupta, Susanta Kar   +7 more
doaj   +1 more source

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasisResearch in context

EBioMedicine, 2018
Background: Miltefosine has been used successfully to treat visceral leishmaniasis (VL) in India, but it was unsuccessful for VL in a clinical trial in Brazil.
Juliana B.T. Carnielli, Kathryn Crouch, Sarah Forrester, Vladimir Costa Silva, Sílvio F.G. Carvalho, Jeziel D. Damasceno, Elaine Brown, Nicholas J. Dickens, Dorcas L. Costa, Carlos H.N. Costa, Reynaldo Dietze, Daniel C. Jeffares, Jeremy C. Mottram   +12 more
doaj   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

Nano Select, Volume 7, Issue 2, February 2026.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri, Dominique de Jong‐Hoogland, Martin B. Ulmschneider   +2 more
wiley   +1 more source

A Replicative In Vitro Assay for Drug Discovery against Leishmania donovani. [PDF]

, 2016
The protozoan parasite Leishmania donovani is the causative agent of visceral leishmaniasis, a disease potentially fatal if not treated. Current available treatments have major limitations, and new and safer drugs are urgently needed.
Aguilar, Fernando, Cantizani, Juan, Coteron, Jose M, Croft, Simon L, Díaz, Rosario, Martin, Julio J, Peña, Imanol, Presa, Jesús L, Tegazzini, Diana, Yardley, Vanessa   +9 more
core   +1 more source

Unveiling the Leishmanicidal Mechanism of 4‐Nerolidylcatechol Isolated From Piper peltatum Against Leishmania infantum

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The present study assessed the leishmanicidal activity of 4‐nerolidylcatechol (4‐NC) (1) isolated from Piper peltatum leaves against promastigotes and amastigotes of Leishmania amazonensis, L. braziliensis, and L. infantum. The plant was fractionated, leading to the isolation and chemical identification of 4‐NC (1). Biochemical techniques were
Fabiana Brusco Lorenzetti, Rodolfo Bento Balbinot, Danielle Lazarin‐Bidóia, Viviane dos Santos Faiões, Eduardo Caio Torres‐Santos, Celso Vataru Nakamura, Tânia Ueda‐Nakamura, Diógenes Aparício Garcia Cortez, Benedito Prado Dias Filho   +8 more
wiley   +1 more source

Zinc Oxide Nanomaterials: Green Synthesis, Properties, and Potentials in Active Food Packaging, Edible Coatings, and Nanomedicine Applications

ChemistrySelect, Volume 11, Issue 1, 8 January 2026.
This study critically analyzed the main advances in ZnO nanomaterials obtained from different synthetic approaches (mediated by plants, microbes and seaweeds), and their functional and biological properties were prospected for applications in the food and nanomedicine sector.
Italo Rennan Sousa Vieira, Ana Carolina de Morais Mirres, Carlos Adam Conte‐Junior   +2 more
wiley   +1 more source

Miltefosine induces metacaspase and PARP genes expression in Leishmania infantum

Brazilian Journal of Infectious Diseases, 2011
Objectives: Apoptosis is the process of programmed cell death (PCD) that occurs in both animal and plant cells. Protozoan parasites possess metacaspase and these caspase-related proteases could be involved in the PCD pathways in these organisms ...
Shahram Khademvatan, Mohammad Javad Gharavi, Jasem Saki   +2 more
doaj   +1 more source

Combination Treatment for Visceral Leishmaniasis Patients Coinfected with Human Immunodeficiency Virus in India. [PDF]

, 2015
BACKGROUND: There are considerable numbers of patients coinfected with human immunodeficiency virus (HIV) and visceral leishmaniasis (VL) in the VL-endemic areas of Bihar, India. These patients are at higher risk of relapse and death, but there are still
Boelaert, Marleen, Burza, Sakib, Das, Pradeep, Isaakidis, Petros, Kumar, Deepak, Lima, Marıa Angeles, Mahajan, Raman, Mitra, Gaurab, Pandey, Krishna, Sagili, Karuna D, Sunyoto, Temmy, Van Geertruyden, Jean-Pierre   +11 more
core   +1 more source