Results 61 to 70 of about 5,633 (170)

Comparing the Effects of Topical Miltefosine and Glucantime in Treatment of Cutaneous Leishmaniasis

مجله دانشکده پزشکی اصفهان, 2014
Background: Due to the limited number of studies, failure to adequately investigating the impact of miltefosine in the treatment of cutaneous leishmaniasis, and the fact that faster recovery of injuries causes less scarring for the patient, the present ...
Ali Asilian, Shaghayegh Omrani, Mohammad Ail Nilforoushzadeh   +2 more
doaj  

Estudo comparativo entre miltefosina oral e antimoniato de N-metil glucamina parenteral no tratamento da leishmaniose experimental causada por Leishmania (Leishmania) amazonensis Comparative study between oral miltefosine and parenteral N-metil glucamine antimoniate for the treatment of experimental leishmaniasis caused Leishmania (Leishmania) amazonensis

Revista da Sociedade Brasileira de Medicina Tropical, 2008
Vinte e cinco camundongos infectados com Leishmania amazonensis foram tratados com antimoniato de N-metil glucamina e miltefosina oral. Critérios: medidas das patas, pesquisa de amastigotas e culturas após-tratamento.
Arnoldo Velloso da Costa Filho, Íris Campos Lucas, Raimunda Nonata Ribeiro Sampaio   +2 more
doaj   +1 more source

Oral miltefosine for refractory Acanthamoeba keratitis

American Journal of Ophthalmology Case Reports, 2019
Purpose: To report the first case of Acanthamoeba keratitis treated with oral miltefosine in the United States. Observations: A 17-year-old female with a history of orthokeratology contact lens wear presented after five months of left eye pain, redness ...
Kristin E. Hirabayashi, Charles C. Lin, Christopher N. Ta   +2 more
doaj   +1 more source

Thermoterapy effective and safer than miltefosine in the treatment of cutaneous leishmaniasis in Colombia

Revista do Instituto de Medicina Tropical de São Paulo, 2013
In Colombia, pentavalent antimonials and miltefosine are the drugs of choice for the treatment of cutaneous leishmaniasis; however, their toxicity, treatment duration, (treatment adherence problems), cost, and decreased parasite sensitivity make the ...
Liliana López, Claudia Cruz, Gonzalo Godoy, Sara M. Robledo, Iván D. Vélez   +4 more
doaj   +1 more source

From lipid biophysics to first-in human test: topical liposomal treatment for cutaneous leishmaniasis

Precision Nanomedicine
Cutaneous leishmaniasis (CL) remains a major neglected disease with limited therapeutic op-tions and expanding geographic distribution. To develop a safe, accessible local treatment, we formulated topical Miltefosine gels incorporating different types of
Dolores Catalina Carrer
doaj   +1 more source

No evidence for cardiotoxicity of miltefosine

Anais Brasileiros de Dermatologia, 2022
openaire   +4 more sources

Evaluation of In Vitro Cytotoxic and Apoptotic Effects of Miltefosine on the Toxoplasma gondii RH Strain

Iranian Journal of Parasitology
Background: We aimed to investigate the cytotoxic and apoptotic effects of miltefosine on Toxoplasma gondii RH strain by various techniques. Methods: The study was conducted at the Department of Parasitology and Mycology, Urmia University of Medical ...
Shahram Khademvatan, Elham Yousefi, Negar Asadi, Esmaeil Abasi   +3 more
doaj  

Clinical, histopathological and parasitological follow-up of dogs naturally infected by Leishmania infantum before and after miltefosine treatment and associated therapies.

PLoS ONE
In Brazil, Visceral Leishmaniases is caused by Leishmania infantum, and domestic dogs are the main reservoirs in its urban transmission cycle. As an alternative to euthanizing dogs, miltefosine has been used to treat canine visceral leishmaniasis since ...
Amábilli de Souza Rosar, Carolina Leite Martins, Álvaro Menin, Carolina Reck, Edmundo Carlos Grisard, Glauber Wagner, Mário Steindel, Patricia Hermes Stoco, Patricia Flavia Quaresma   +8 more
doaj   +1 more source

Unmasking the Mechanism behind Miltefosine: Revealing the Disruption of Intracellular Ca²⁺ Homeostasis as a Rational Therapeutic Target in Leishmaniasis and Chagas Disease

Biomolecules
Originally developed as a chemotherapeutic agent, miltefosine (hexadecylphosphocholine) is an inhibitor of phosphatidylcholine synthesis with proven antiparasitic effects.
Gustavo Benaim, Alberto Paniz-Mondolfi
doaj   +1 more source

Miltefosine Drug Concerns [PDF]

Clinical Infectious Diseases, 2013
Subhash C, Arya, Nirmala, Agarwal
openaire   +2 more sources