Results 181 to 190 of about 76,021 (334)

Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses

Experimental Physiology, EarlyView.
Abstract Uteroplacental insufficiency impairs kidney development and programs male‐onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting that the lifestyle of growth‐restricted females can have further influence on F2 kidney ...
Jessica F. Briffa, Sogand Gravina, Viktoria F. Richter, Dayana Mahizir, Kristina Anevska, Yeukai T. M. Mangwiro, James S. M. Cuffe, Fadi Charchar, Glenn D. Wadley, Deanne H. Hryciw, Karen M. Moritz, Mary E. Wlodek   +11 more
wiley   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source

Additional file 1 of Population-based estimates of the global prevalence and carrier frequency of apparent mineralocorticoid excess caused by 11β-hydroxysteroid dehydrogenase type 2 deficiency

Nipith Charoenngam, Chalermkiat Kansuttiviwat, Palinee Chinsawangwatanakul   +2 more
openalex   +1 more source

Mineralocorticoid regulation of cell function: the role of rapid signalling and gene transcription pathways [PDF]

, 2016
Gregory S Y Ong, Morag J. Young
openalex   +1 more source

Early life stress and disruption of the ageing trajectory in female rats: Insights into the origins and mechanisms underlying the risk of hypertension

Experimental Physiology, EarlyView.
Abstract Menopause increases the risk of hypertension in women, yet the factors contributing to this important change remain unclear. Because early life stress has persistent and sex‐specific consequences on health, we hypothesized that ageing reveals the latent effects of neonatal maternal separation (NMS) on cardiovascular homeostasis in female rats.
Danuzia Ambrozio‐Marques, Loralie Mei Guay, Alicia A. Koogler, Tim D. Ostrowski, Aline M. Arlindo de Souza, Kathryn Sandberg, Richard Kinkead   +6 more
wiley   +1 more source

The Case for Combination Treatment of CKD in Type 2 Diabetes Mellitus. [PDF]

Kidney Int Rep
Curovic VR.
europepmc   +1 more source

A Case of Worsened Refractory Ascites due to Prednisolone Administration for Stricture Prevention after Endoscopic Submucosal Dissection for Extensive Early Esophageal Cancer: Case Report and Literature Review

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Endoscopic submucosal dissection (ESD) is widely used for early esophageal cancer, even in patients with liver cirrhosis (LC). Corticosteroids, administered orally or by local injection, are often used to prevent post‐ESD esophageal stricture. However, their safety in patients with decompensated LC and refractory ascites remains unclear. A man
Yuki Tamura, Masanori Sekiguchi, Kaho Honda, Yu Maruyama, Kenta Ito, Makiko Inoue, Mitsuhiko Shibasaki, Daichi Takizawa, Hirotaka Arai, Toshio Uraoka   +9 more
wiley   +1 more source

Precocial Weaning Influences Anxiety, Social and Maternal Care but Not Cognition in African Striped Mice, Rhabdomys dilectus chakae

Developmental Psychobiology, Volume 68, Issue 2, March 2026.
ABSTRACT Weaning is a stressful stage in the lives of young mammals. Early weaning, in particular, can lead to long‐lasting physiological and psychological changes. We investigated the effects of precocial weaning on anxiety, social behavior, cognition, and maternal behavior in adult African four‐striped mice (Rhabdomys dilectus chakae). Mice weaned at
Maria K Oosthuizen, Neville Pillay
wiley   +1 more source

Combination therapy with mineralocorticoid receptor antagonists and SGLT2 inhibitors versus SGLT2 inhibitor monotherapy in chronic kidney disease: an updated meta-analysis of randomized controlled trials. [PDF]

BMC Nephrol
Muhammad Daniyal S, Ajaz H, Riaz M, Murad Khatoon N, Aftab Z, Tauqir Gondal H, Gul I, Sarwar M, Batool F, Fahim SL, Noor A, Khalid A, Ashraf DA, Jabarkhil R.   +13 more
europepmc   +1 more source

B004 Effects of the selective mineralocorticoid receptor antagonist, eplerenone, in a model of aldosterone-induced hypertension and cardiac fibrosis [PDF]

, 1998
Gregory E. Frierdich
openalex   +1 more source