Results 171 to 180 of about 77,372 (337)

Potassium binders and continuation of renin–angiotensin system inhibitors/mineralocorticoid receptor antagonist in chronic kidney disease and heart failure (the DEMONSTRATE database)

Journal of Internal Medicine, EarlyView.
Abstract Introduction Hyperkalaemia is a serious complication in patients with chronic kidney disease (CKD) and heart failure (HF), often leading to the discontinuation of renin–angiotensin–aldosterone system inhibitors (RAASi; renin‐angiotensin system inhibitors [RASi] and mineralocorticoid receptor antagonists [MRAs]) despite their cardiorenal ...
Hans Furuland, Anders Olof Larsson, Milica Uhde, Kristel Parv, Matilda Almstedt, Thomas Cars, Maria K. Svensson   +6 more
wiley   +1 more source

The central role of mineralocorticoids in the development of salt-sensitive hypertension

, 2004
Rhianna Aleka Derenick
openalex   +1 more source

Global kidney health: Are we failing the silent pandemic?

Journal of Internal Medicine, EarlyView.
Abstract Chronic kidney disease (CKD), although not infectious, has a sharply rising global incidence, alarming rates of death and disability, and the potential to disrupt health systems and economies. Thus, it demands the urgency and global attention of past pandemics.
Taewon Yi, Daniel V. O'Hara, Adeera Levin   +2 more
wiley   +1 more source

Drug–Drug Interactions of the Nonsteroidal Mineralocorticoid Receptor Antagonist Apararenone With Midazolam, Warfarin, and Digoxin: A Phase 1 Studies in Healthy Volunteers

, 2020
Tadakatsu Nakamura, H. Shimizu, Atsuhiro Kawaguchi   +2 more
openalex   +1 more source

Rapid shear stress-dependent ENaC membrane insertion is mediated by the endothelial glycocalyx and the mineralocorticoid receptor [PDF]

, 2022
Zülfü C. Cosgun, Magdalena Sternak, Benedikt Fels, Anna Bar, Grzegorz Kwiatkowski, Marta Z. Pacia, Lisbeth Herrnböck, Martina Lindemann, Johannes Stegbauer, Sascha Höges, Stefan Chłopicki, Kristina Kusche‐Vihrog   +11 more
openalex   +1 more source

A mini‐review of chronic suppression of the hypothalamic–pituitary–adrenal axis in animals with P‐glycoprotein deficiency

Journal of Small Animal Practice, EarlyView.
This mini‐review describes the pathophysiology of the disrupted hypothalamic–pituitary–adrenal axis in dogs, and probably cats, with the MDR1 (ABCB1) mutation, ABCB1‐1Δ in dogs and ABCB11930‐1931del TC in cats. Clinical consequences in affected animals are discussed and therapeutic interventions to consider are presented.
K. L. Mealey
wiley   +1 more source

Exercise Capacity and the Force Frequency Relationship in Multi‐Point Versus Single‐Point Pacing: A Randomized Trial

Pacing and Clinical Electrophysiology, EarlyView.
Abstract Background Quadripolar left ventricular (LV) epicardial leads capable of multipoint pacing (MPP) may have an advantage over conventional bipolar leads for delivering cardiac resynchronization therapy (CRT) by stimulating the lateral LV wall from two distinct locations simultaneously.
Nawaz Z. Safdar, Ria M. Gadani, Charlotte A. Cole, Judith E. Lowry, Stephe Kamalathasan, Sushma Datla, Oliver I. Brown, Nithusa Rahunathan, Maria F. Paton, Mark T. Kearney, Sam Straw, Klaus K. Witte, John Gierula   +12 more
wiley   +1 more source

The mineralocorticoid receptor as a modulator of innate immunity and atherosclerosis [PDF]

, 2018
Charlotte D.C.C. van der Heijden, Jaap Deinum, Leo A. B. Joosten, Mihai G. Netea, Niels P. Riksen   +4 more
openalex   +1 more source

Finerenone in mildly reduced or preserved ejection fraction and chronic kidney disease: a narrative review. [PDF]

Egypt Heart J
Faheem MSB, Qurat Ul Ain H, Rauf A, Faheem Q, Najmi OEM.   +4 more
europepmc   +1 more source

Mineralocorticoid receptor blockade improves glucocorticoid‐induced skin atrophy but partially ameliorates anti‐inflammatory actions in an irritative model in human skin explants

, 2017
Julia Boix, Van Tuan Nguyen, Nicolette Farman, S. Aractingi, Paloma Pérez   +4 more
openalex   +2 more sources