Results 171 to 180 of about 43,749 (262)

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Steroidome Dysregulation and Complement C4 Copy Number Variation in Men With Central Serous Chorioretinopathy. [PDF]

Invest Ophthalmol Vis Sci
Zola M, Han JH, Quinodoz M, Bousquet E, Matet A, Kowalczuk L, Daruich A, Zhao M, Ullah M, Rivolta C, Eandi C, Arsenijevicz Y, Pussard E, Behar-Cohen F.   +13 more
europepmc   +1 more source

Encounters With Traditional Medicine and Further Multidisciplinary and International Cooperation

Traditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
ABSTRACT Background The integration of traditional medicine (TM) into modern healthcare has gained global momentum. Following the inclusion of TM in the 11th revision of the International Classification of Diseases, multidisciplinary and international cooperation has become increasingly essential.
Kokoro Ichihara, Ryota Sakoda, Yuto Matsuura, Hong‐Wook Choi, Toshiaki Makino, Tomoko Suzuki, Shin Takayama   +6 more
wiley   +1 more source

Long‐term follow‐up of chronic central serous chorioretinopathy patients receiving oral eplerenone and half‐dose photodynamic therapy in the SPECTRA trial: SPECTRA trial report No. 4

Acta Ophthalmologica, Volume 104, Issue 5, Page e565-e577, August 2026.
Abstract Purpose Assessing the 24‐month treatment outcome of half‐dose photodynamic therapy (PDT) or oral eplerenone in chronic central serous chorioretinopathy (cCSC). Methods Multicentre randomized clinical trial included cCSC patients from the SPECTRA trial who were randomized to receive half‐dose PDT or oral eplerenone.
Helena M. A. Feenstra, Issam El Mansori, Thomas J. van Rijssen, Roula Tsonaka, Roselie M. H. Diederen, Carel B. Hoyng, Reinier O. Schlingemann, Camiel J. F. Boon, Elon H. C. van Dijk   +8 more
wiley   +1 more source

Cardiovascular risk in primary aldosteronism: inflammatory drivers, residual risk, and emerging combination strategies. [PDF]

Front Endocrinol (Lausanne)
Liu H, Wu Z, Liu X, Hu Y, Zhang K, Shang J.   +5 more
europepmc   +1 more source

The Effects of Combined Antihypertensive and Antidiabetic Therapies on Cardiovascular Outcomes: A Systematic Review and Meta‐Analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6874-6887, August 2026.
ABSTRACT Aims Hypertension and diabetes frequently coexist, yet the net clinical impact of intentionally combining antihypertensive (AHTN) and antidiabetic (ADA) therapies on cardiovascular (CV) outcomes is uncertain. Here we quantified the effects of AHTN and ADA co‐therapy on CV and blood pressure (BP)/heart rate (HR) outcomes.
Wan Chin Hsieh, Brandon Michael Henry, István Édes   +2 more
wiley   +1 more source

Multi‐Parametric Magnetic Resonance Imaging to Assess Empagliflozin Effect on the Kidneys in People With Type 2 Diabetes Mellitus: A Pilot Clinical Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7416-7429, August 2026.
ABSTRACT Aims Empagliflozin is renoprotective in Type 2 diabetes mellitus (T2DM). Our primary aim was to assess empagliflozin's effect on glomerular filtration rate and renal vascular resistance using multiparametric MRI (MpMRI). Our secondary aim was to assess the impact of empagliflozin on additional MpMRI‐derived metrics including markers of tissue ...
Ruth P. Lim, Salma Qassin, Lucy McKenna, Emma Hornsey, Dominic Italiano, Leonid Churilov, Richard J. MacIsaac, Jas‐mine Seah, Elif I. Ekinci, The Austin EMPA‐MRI Study Group   +9 more
wiley   +1 more source

Comment on Rossing et al. Nuances in Interpretation: Assessing the Interaction Between Semaglutide and MRAs in the FLOW Trial. [PDF]

Diabetes Care
Liu Q, Yang JF, Wang ZG.
europepmc   +1 more source

Early Hemolysis, Myolysis and Renal Stress Following Pentaspline Pulsed Field Versus Radiofrequency Ablation of Atrial Fibrillation

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Serial biomarker assessment in 40 patients undergoing first‐time pulmonary vein isolation showed greater hemolysis and myocardial myolysis after FARAPULSE pentaspline single‐shot pulsed field ablation than after radiofrequency ablation. Myoglobin changes were associated with transient changes in renal function, albeit these exploratory correlations do ...
Paul Felix Harbich, Lisa Auer, Florian Tinhofer, Achim Leo Burger, Tobias Eberl, Patrick Weltler, Stephan Dobner, Alexander Geppert, Kurt Huber, Christoph Clemens Kaufmann   +9 more
wiley   +1 more source