Results 161 to 170 of about 77,372 (337)

Disturbances of sodium in critically ill adult neurologic patients: A clinical review [PDF]

open access: yes, 2006
Disorders of sodium and water balance are common in critically ill adult neurologic patients. Normal aspects of sodium and water regulation are reviewed. The etiology of possible causes of sodium disturbance is discussed in both the general inpatient and
Crocker, M   +3 more
core  

Effects of Vicadrostat/Empagliflozin in People With Chronic Kidney Disease: Metabolic Subgroup Analyses

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims In a phase 2 trial, the efficacy and safety of the highly selective aldosterone synthase inhibitor vicadrostat, alone or with empagliflozin, were investigated in people with chronic kidney disease (CKD) with or without type 2 diabetes (T2D). Materials and Methods Adults (n = 586) with CKD (estimated glomerular filtration rate [eGFR] 30 to
David Z. I. Cherney   +14 more
wiley   +1 more source

A COMPARATIVE ASSESSMENT OF THE EFFECT OF MINERALOCORTICOID RECEPTOR ANTAGONISTS ON CHANGES IN GALECTIN-3 AND MMP-1 FIBROSIS MARKERS IN PATIENTS WITH CHRONIC CARDIAC FAILURE COMBINED WITH TYPE 2 DIABETES MELLITUS WITH MANIFESTATIONS OF MYOCARDIUM DYSSYNCHRONY

open access: yesJournal of V. N. Karazin Kharkiv National University: Series Medicine, 2016
A comparative assessment of the effect of mineralocorticoid receptor antagonists on changes in galectin 3 and matrix metalloproteinase 1 fibrosis markers has been carried out on 106 examinations (average age (69 + 10.37) years) with type 2 DM and CCF of ...
T. A. Rudenko
doaj  

Preventive Effect of Mineralocorticoid Receptor Antagonists Against Proteinuria Induced by Atezolizumab Plus Bevacizumab Therapy in Hepatocellular Carcinoma: A Multicenter Retrospective Study

open access: yesHepatology Research, EarlyView.
Mineralocorticoid receptor antagonists are known to reduce proteinuria in chronic kidney disease, but their effectiveness in preventing bevacizumab‐related proteinuria has not been well established. In the present multi‐institutional retrospective study, we found that these agents significantly delay the onset of moderate or higher grade proteinuria ...
Tomoki Hori   +17 more
wiley   +1 more source

Practical recommendations for treating patients with chronic kidney disease in Australia: a multidisciplinary approach

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Chronic kidney disease (CKD) is a significant public health challenge in Australia, affecting ~10% of the adult population and contributing to substantial morbidity and mortality. Diabetes, hypertension, cardiovascular disease and CKD frequently co‐exist; therefore, a multidisciplinary approach is necessary to manage these ...
M. P. Schlaich   +7 more
wiley   +1 more source

Oral mineralocorticoid antagonists for recalcitrant central serous chorioretinopathy

open access: yesClinical Ophthalmology, 2015
Eric K Chin, David RP Almeida, C Nathaniel Roybal, Philip I Niles, Karen M Gehrs, Elliott H Sohn, H Culver Boldt, Stephen R Russell, James C FolkDepartment of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USAPurpose: To evaluate ...
Chin EK   +8 more
doaj  

Effect of sodium–glucose cotransporter 2 inhibitors on heart failure readmission in older patients with diabetes: A Japanese claims‐based cohort study

open access: yesJournal of Diabetes Investigation, EarlyView.
SGLT2 inhibitor use at discharge was associated with a reduced risk of heart failure readmission in elderly patients with diabetes, with no significant differences among individual agents. ABSTRACT Aims To evaluate the effect of sodium–glucose cotransporter 2 inhibitor (SGLT2i) administration at hospital discharge on heart failure (HF) readmission ...
Kazuya Hiura   +3 more
wiley   +1 more source

Primary Adrenal Insufficiency: Managing Mineralocorticoid Replacement Therapy [PDF]

open access: hybrid, 2017
Daniela Espósito   +2 more
openalex   +1 more source

Update of the EuroGuiDerm evidence‐based guideline for the treatment of acne—Short version

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The 2025 EuroGuiDerm guideline update provides evidence‐based recommendations for acne management, addressing systemic antibiotics, systemic isotretinoin, hormonal therapies including spironolactone and contraceptives, and new topical agents. Key considerations include treatment duration, safety, pregnancy‐specific guidance and minimizing antibiotic ...
Alexander Nast   +22 more
wiley   +1 more source

Expression of corticoid‐regulatory genes in the gills of Atlantic salmon (Salmo salar) parr and smolt and during salinity acclimation

open access: yesJournal of Fish Biology, EarlyView.
Abstract In teleost fishes, cortisol is the major corticoid and has both glucocorticoid and mineralocorticoid actions. However, how fish tissues discriminate between these distinct corticosteroid actions is unclear. In mammals, the major factors responsible for intracellular corticosteroid regulation are glucocorticoid receptors (grs) and the ...
Makoto Kusakabe   +4 more
wiley   +1 more source

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