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Mineralocorticoid receptor antagonists (MRAs)
2014Abstract The final process in the renin–angiotensin–aldosterone system (RAAS) is the production of the mineralocorticoid aldosterone in the adrenal glands. Aldosterone has an important role in the pathophysiology of heart failure, and concentrations of aldosterone are 20-fold higher in patients with HF compared to normal individuals ...
Roy S. Gardner +2 more
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Mineralocorticoid receptor antagonists: a patent evaluation of US20150284376A1
Expert Opinion on Therapeutic Patents, 2016Recent clinical studies showed that mineralocorticoid receptor antagonists are able to markedly reduce the overall and cardiovascular mortality in patients with left ventricular systolic dysfunction and mild or severe symptoms of chronic heart failure (HF).
Matthieu, Collin, Frédéric, Jaisser
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Mineralocorticoid receptor antagonists (MRAs)
Abstract The final process in the renin–angiotensin–aldosterone system (RAAS) is the production of the mineralocorticoid aldosterone in the adrenal glands. Aldosterone has an important role in the pathophysiology of heart failure, and concentrations of aldosterone are 20-fold higher in patients with HF compared to normal individuals ...Roy S. Gardner +3 more
openaire +1 more source

