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Mineralocorticoid receptor antagonists (MRAs)

2014
Abstract The final process in the renin–angiotensin–aldosterone system (RAAS) is the production of the mineralocorticoid aldosterone in the adrenal glands. Aldosterone has an important role in the pathophysiology of heart failure, and concentrations of aldosterone are 20-fold higher in patients with HF compared to normal individuals ...
Roy S. Gardner   +2 more
openaire   +1 more source

Mineralocorticoid receptor antagonists: a patent evaluation of US20150284376A1

Expert Opinion on Therapeutic Patents, 2016
Recent clinical studies showed that mineralocorticoid receptor antagonists are able to markedly reduce the overall and cardiovascular mortality in patients with left ventricular systolic dysfunction and mild or severe symptoms of chronic heart failure (HF).
Matthieu, Collin, Frédéric, Jaisser
openaire   +2 more sources

Mineralocorticoid receptor antagonists (MRAs)

Abstract The final process in the renin–angiotensin–aldosterone system (RAAS) is the production of the mineralocorticoid aldosterone in the adrenal glands. Aldosterone has an important role in the pathophysiology of heart failure, and concentrations of aldosterone are 20-fold higher in patients with HF compared to normal individuals ...
Roy S. Gardner   +3 more
openaire   +1 more source

Benefits of the Non-Steroidal Mineralocorticoid Receptor Antagonist Finerenone in Metabolic Syndrome-Related Heart Failure with Preserved Ejection Fraction

International Journal of Molecular Sciences, 2023
Frédéric Jaisser   +2 more
exaly  

Mineralocorticoid receptor antagonists

2012
CRESPO ALEJANDRO   +16 more
openaire   +11 more sources

Characterization of Mineralocorticoid Receptor Antagonist Therapy Initiation in High-Risk Patients With Heart Failure

Circulation: Cardiovascular Quality and Outcomes, 2017
Bertram Pitt   +2 more
exaly  

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