Results 241 to 250 of about 26,548 (293)

Protective Effects of Selective Mineralocorticoid Receptor Antagonist in Alport Syndrome on Top of Renin-Angiotensin-System/ Sodium-Glucose Transporter 2 Blockade. [PDF]

Kidney Int Rep
Song ZR, Li Y, Zhang H, Zhou XJ.
europepmc   +1 more source

The urinary albumin‐to‐creatinine ratio can direct personalized prevention and treatment for cardiovascular and chronic kidney disease

Journal of Internal Medicine, Volume 299, Issue 4, Page 444-466, April 2026.
Abstract Increased urinary albumin excretion is a strong predictor for cardiovascular events in persons with and without decreased glomerular filtration rate and can be assessed with the urinary albumin‐to‐creatinine ratio (UACR), which is a selective, sensitive, and convenient method for patients.
Holly J. Kramer, George L. Bakris
wiley   +1 more source

GLP‐1 Receptor Agonists for the Prevention of New‐Onset Heart Failure: A Systematic Review and Meta‐Analysis of Placebo‐Controlled Randomized Clinical Trials

Obesity Reviews, Volume 27, Issue 4, April 2026.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) improve outcomes in heart failure (HF) with preserved ejection fraction. Whether GLP‐1 RA prevent new‐onset HF in Type 2 diabetes or obesity requires further investigation. Methods We performed an updated meta‐analysis of randomized placebo‐controlled trials (RCT) of treatment ...
João Sérgio Neves, Carolina B. Lobato, Ana Rita Leite, Catarina Vale, Francisco Vasques‐Nóvoa, Francisca Saraiva, Adelino Leite‐Moreira, Jens J. Holst, João Pedro Ferreira   +8 more
wiley   +1 more source

Early life stress and disruption of the ageing trajectory in female rats: Insights into the origins and mechanisms underlying the risk of hypertension

Experimental Physiology, Volume 111, Issue 4, Page 1781-1795, 1 April 2026.
Abstract Menopause increases the risk of hypertension in women, yet the factors contributing to this important change remain unclear. Because early life stress has persistent and sex‐specific consequences on health, we hypothesized that ageing reveals the latent effects of neonatal maternal separation (NMS) on cardiovascular homeostasis in female rats.
Danuzia Ambrozio‐Marques, Loralie Mei Guay, Alicia A. Koogler, Tim D. Ostrowski, Aline M. Arlindo de Souza, Kathryn Sandberg, Richard Kinkead   +6 more
wiley   +1 more source

Mineralocorticoid receptor antagonists reduce inflammatory signaling independent of myofiber mineralocorticoid receptor

Endocrine and Metabolic Science
Jeovanna Lowe, Arden B. Piepho, Chetan K. Gomatam, Peyton Debell, Megan N. Ballinger, Jill A. Rafael-Fortney   +5 more
openaire   +1 more source

Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblasts

Physiological Reports, Volume 14, Issue 8, April 2026.
The effect of oral contraceptives (OCs) on muscle repair is unknown. Using electrical pulse stimulation to simulate damage in C2C12 myoblasts treated with four OC generations (MPA, LNG, DSG, DRP combined with ethinyl estradiol), we assessed proliferation, differentiation, migration, creatine kinase, myogenic proteins, and hormone receptor protein ...
Mai Wageh, Michael Kamal, Gianni Parise
wiley   +1 more source