Results 171 to 180 of about 1,285,117 (188)

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, Volume 105, Issue 3, Page 271-284, September 2026.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Impact of Simultaneous Initiation of Finerenone and Empagliflozin on Albuminuria Irrespective of Baseline HbA1c Levels: A Participant‐Level Exploratory Analysis of the Randomised CONFIDENCE Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 7964-7973, September 2026.
ABSTRACT Aims This prespecified analysis evaluated whether the safety and efficacy of finerenone and a sodium–glucose cotransporter 2 inhibitor (SGLT2i) combination vary by baseline glycated haemoglobin (HbA1c). Materials and Methods Adults with type 2 diabetes and a urinary albumin‐to‐creatinine ratio (UACR) of 100 − < 5000 mg/g, estimated glomerular ...
Janet B. McGill, Jennifer B. Green, Hiddo J. L. Heerspink, Johannes F. E. Mann, Amy K. Mottl, Julio Rosenstock, Peter Rossing, Muthiah Vaduganathan, Masaomi Nangaku, Meike Brinker, Charlie Scott, Katja Rohwedder, Li Li, Na Li, Margarida Seco, Rajiv Agarwal   +15 more
wiley   +1 more source

Left Atrial Reservoir Strain and Heart Failure Rehospitalization Burden in Acute Heart Failure With Atrial Fibrillation

Echocardiography, Volume 43, Issue 9, September 2026.
This graphical abstract summarizes 716 patients with acute heart failure and atrial fibrillation. The left atrial diameter analysis included 691 patients (189 rehospitalization‐first, 118 death‐first, 384 censored); volume index and reservoir strain were available in a 320‐patient single‐center subgroup.
Jumpei Yamamoto, Keijiro Nakamura, Hiromasa Hayama, Yoshinari Enomoto, Masaya Yamamoto, Hidehiko Hara, Hisao Hara, Yukio Hiroi   +7 more
wiley   +1 more source

Withholding Oral Anticoagulation at Discharge and Post‐Discharge Stroke and Bleeding Vulnerability in a Predominantly Older Cohort Hospitalized With Acute Heart Failure and Atrial Fibrillation

Geriatrics &Gerontology International, Volume 26, Issue 9, September 2026.
Among 560 predominantly older patients discharged after acute heart failure with atrial fibrillation, withholding oral anticoagulation was associated with higher ischemic stroke and did not indicate lower bleeding risk. Bleeding risk was significantly higher among patients aged 80 years or older.
Jumpei Yamamoto, Keijiro Nakamura, Hiromasa Hayama, Yoshinari Enomoto, Masaya Yamamoto, Hidehiko Hara, Hisao Hara, Yukio Hiroi   +7 more
wiley   +1 more source

Associations of finerenone with reduced insulin resistance in patients with type 2 diabetes and chronic kidney disease: A real‐world observational study

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1524-1532, September 2026.
This real‐world observational study enrolled 256 patients with type 2 diabetes and chronic kidney disease (T2D‐CKD). After 12 months of finerenone treatment, 45 patients completed follow‐up. Finerenone was associated with significant improvements in insulin resistance markers (HOMA‐IR, TyG index), lipid profile (LDL‐C), glycemic control (HbA1c), and ...
Xin Zhao, Bohan Liu, Ran Sun, Yaxuan Shi, Ya Liu   +4 more
wiley   +1 more source

Developing a machine learning model to predict renal function decline within three years using one‐year longitudinal data in patients with type 2 diabetes

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1506-1513, September 2026.
We developed a machine learning model to predict renal function decline in patients with type 2 diabetes and preserved kidney function. Using one year of routine clinical data, the model forecasts eGFR decline over three years, enabling early identification of high‐risk patients and supporting timely, targeted therapeutic interventions.
Mari Kaneda, Shu Meguro, Kaiken Kimura, Youichiro Harada, Makoto Enomoto, Kaori Hayashi   +5 more
wiley   +1 more source

Sodium zirconium cyclosilicate compared with potassium restriction for hyperkalemia management in type 2 diabetes: The SILVERSTAR trial

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1625-1633, September 2026.
ABSTRACT Aims/Introduction To demonstrate noninferiority of continued sodium zirconium cyclosilicate therapy versus a potassium‐restricted diet in achieving normokalemia at Visit 7 (Days 28–42) in individuals with type 2 diabetes and hyperkalemia, using a noninferiority margin of −10 percentage points (one‐sided α = 0.025).
Masahide Hamaguchi, Junya Hironaka, Hiroshi Okada, Mari Yoneda, Ayaka Kobayashi, Yoshitaka Hashimoto, Aya Kitae, Noriyuki Kitagawa, Akio Kishi, Michiyo Ishii, Mai Asano, Masahiro Yamazaki, Toru Tanaka, Hanako Nakajima, Eiko Sato, Michiaki Fukui   +15 more
wiley   +1 more source

Left Ventricular Wall Thickness and Decrement Evoked Potentials in Ablation of Ischemic Ventricular Tachycardia

Pacing and Clinical Electrophysiology, Volume 49, Issue 9, Page 1341-1348, September 2026.
ABSTRACT Introduction Preprocedural imaging can improve the success rate of ventricular tachycardia (VT) ablation. Left ventricular wall thickness (LVWT) measured by cardiac computed tomography (CT) can be used to identify infarct regions. We sought to determine whether an association exists between left ventricular wall thickness (LVWT) as obtained ...
Alwin B. P. Noordman, Ahmed S. Yassin, Michiel Rienstra, Alexander H. Maass, Yuri Blaauw   +4 more
wiley   +1 more source

Supraphysiological Glucocorticoid Doses and Pitfalls of Annual Biomarker Monitoring in Adults With CAH

Clinical Endocrinology, Volume 105, Issue 3, Page 360-362, September 2026.
Jakob Bolinder, Oskar Ragnarsson, Gudmundur Johansson   +2 more
wiley   +1 more source

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Steroidal and non-steroidal mineralocorticoid receptor antagonists in cardiorenal medicine

European Heart Journal, 2021
Faiez Zannad, Rajiv Agarwal, Takashi Wada   +2 more
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