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Abstract Adrenal vein sampling (AVS) is the cornerstone diagnostic procedure for subtype differentiation in primary hyperaldosteronism, guiding therapeutic decision‐making and offering the possibility of curative surgery to a subset of patients.
Aura D. Herrera‐Martínez +15 more
wiley +1 more source
Abstract Motivation for social or resource‐related rewards is regulated by areas of the brain that control executive functioning and regulate attention, including the prefrontal cortex (PFC) and temporoparietal junction (TPJ). Testosterone and cortisol are two steroid hormones that influence behaviors related to motivation in social competition and are
Kathleen V. Casto +3 more
wiley +1 more source
Kidney Disease and Mineralocorticoid Receptor
openaire +3 more sources
Emerging Medical Therapies for Primary Aldosteronism. [PDF]
Vibhatavata P, Turcu AF.
europepmc +1 more source
Human DRG Glucocorticoid Receptor Profiling Reveals Targets for Regionally Delivered Steroid Analgesia. [PDF]
Mousa SA +8 more
europepmc +1 more source
Finerenone in mildly reduced or preserved ejection fraction and chronic kidney disease: a narrative review. [PDF]
Faheem MSB +4 more
europepmc +1 more source
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Current Hypertension Reports, 2020
Recently, nonsteroidal mineralocorticoid receptor (MR) antagonists (MRAs), which have been proposed to be called MR blockers (MRBs), have become available for clinical use, but their clinical role is unknown. We reviewed the clinical roles of MRAs and MRBs based on previous knowledge and as demonstrated in representative clinical trials.Steroidal MRAs,
Daisuke, Sueta +2 more
openaire +2 more sources
Recently, nonsteroidal mineralocorticoid receptor (MR) antagonists (MRAs), which have been proposed to be called MR blockers (MRBs), have become available for clinical use, but their clinical role is unknown. We reviewed the clinical roles of MRAs and MRBs based on previous knowledge and as demonstrated in representative clinical trials.Steroidal MRAs,
Daisuke, Sueta +2 more
openaire +2 more sources
Mineralocorticoid receptor antagonists
Current Hypertension Reports, 2007With an increasingly aging population, the need for effective treatment of cardiovascular diseases (eg, heart failure, hypertension, and ischemic heart disease) cannot be overemphasized. The vital importance of mineralocorticoid receptor antagonists for treating cardiovascular conditions has only been appreciated in the last decade. The re-emergence of
Parthasarathy, Hari Krishnan +1 more
openaire +3 more sources
Adipocyte Mineralocorticoid Receptor
2019Mineralocorticoid receptor (MR) has been recently identified in adipose tissue, where its excessive activation contributes to several metabolic derangements often observed in obesity and metabolic syndrome. Recent findings support the existence of a bidirectional cross-talk between adipose tissue and adrenal glands, contributing to obesity-related ...
Infante M. +4 more
openaire +4 more sources
Rapid mineralocorticoid receptor trafficking
Steroids, 2014The mineralocorticoid receptor (MR) is a ligand-dependent transcription factor that physiologically regulates water-electrolyte homeostasis and controls blood pressure. The MR can also elicit inflammatory and remodeling processes in the cardiovascular system and the kidneys, which require the presence of additional pathological factors like for example
M, Gekle +4 more
openaire +2 more sources

