Results 231 to 240 of about 31,334 (301)

Prioritising research on endocrine disruption in the marine environment: a global perspective

open access: yesBiological Reviews, Volume 101, Issue 2, Page 848-868, April 2026.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto   +23 more
wiley   +1 more source

New roles of aldosterone and mineralocorticoid receptors in cardiovascular disease: translational and sex-specific effects.

open access: yesAm J Physiol Heart Circ Physiol, 2018
Davel AP   +4 more
europepmc   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2582-2593, April 2026.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Effect of lixisenatide on arterial stiffness in people with type 2 diabetes and kidney disease: Results of a randomised controlled trial

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2953-2961, April 2026.
Abstract Objective People with chronic kidney disease (CKD) and diabetes are at high risk of cardiovascular disease (CVD). Aortic pulse wave velocity (Ao‐PWV) is an independent predictor of CVD. Cardiovascular outcome trials (CVOTs) with glucagon like peptide‐1 receptor agonist (GLP‐1 RA) class demonstrate notable differences, with lixisenatide having ...
Nikolaos Fountoulakis   +8 more
wiley   +1 more source

SGLT2 inhibitors and mortality in older adults with diabetic kidney disease: A target trial emulation study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3126-3136, April 2026.
Abstract Aims Randomized controlled trials on sodium‐glucose cotransporter 2 (SGLT2) inhibitors have yielded inconsistent findings regarding mortality benefits. It remains unclear whether, and in which subgroups, SGLT2 inhibitors confer survival benefits in older adults with diabetic kidney disease (DKD).
Tatsuhiko Azegami   +16 more
wiley   +1 more source

Comparative effectiveness of pharmacotherapy for heart failure with preserved ejection fraction: A systematic review and network meta‐analysis

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3137-3145, April 2026.
Abstract Aim Heart failure with preserved ejection fraction (HFpEF) presents a therapeutic challenge, characterised by a paucity of validated treatments. Emerging data suggest that targeting adiposity is central to HFpEF pathogenesis. We conducted an updated network meta‐analysis to compare the efficacy of emerging and established HFpEF therapies ...
Szu‐Han Chen   +7 more
wiley   +1 more source

Associations of 24‐Hour Urinary Sodium, Potassium Excretion and Sodium‐to‐Potassium Ratio With Longitudinal Home Blood Pressure Control in Patients With Apparent Treatment‐Resistant Hypertension

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Dietary sodium and potassium intake are key determinants of blood pressure (BP) control in hypertensive patients. However, their associations with longitudinal home BP control in patients with apparent treatment‐resistant hypertension (aTRH) remain unclear.
Weikang Bian   +6 more
wiley   +1 more source

Mechanisms of hesperetin in alleviating diabetic nephropathy: Network pharmacology, molecular docking, and experimental validation

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 4, Page 576-587, April 2026.
Hesperetin increases cell viability and reduces cell apoptosis, ferroptosis, release of inflammatory cytokines, and oxidative stress of human kidney tubular cells via repressing IGF1R expression. ABSTRACT Background Diabetic nephropathy (DN) accounts for approximately 50% of chronic kidney disease cases.
Yiwen Guo   +4 more
wiley   +1 more source

The Voice of a Disease: Why Food Noise Can No Longer Be Ignored!

open access: yes
Obesity, Volume 34, Issue 4, Page 759-761, April 2026.
Abdulhameed Alhazmi, Carel W. le Roux
wiley   +1 more source

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