Results 31 to 40 of about 7,219 (278)

The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]

, 1993
There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Wehling, Martin, Theisen, Karl, Eisen, Christoph, Aktas, Janet, Christ, Michael   +4 more
core   +1 more source

Effect of mineralocorticoids on collecting duct hydrogen ion secretion in the rabbit [PDF]

, 1981
The purpose of this study was to elucidate the mechanism whereby a potassium infusion led to an elevation in the urine minus blood (U – B) [Formula: see text] difference in alkaline urine of the rabbit. Rabbits given 9α-flurohydrocortisone 16 h prior to
B.J. Stinebaugh, W. L. M. Robson, M. B. Goldstein, M. L. Halperin   +3 more
core   +1 more source

Comparison of stress-induced changes in adults and pups: is aldosterone the main adrenocortical stress hormone during the perinatal period in rats? [PDF]

PLoS ONE, 2013
Positive developmental impact of low stress-induced glucocorticoid levels in early development has been recognized for a long time, while possible involvement of mineralocorticoids in the stress response during the perinatal period has been neglected ...
János Varga, Szilamér Ferenczi, Krisztina J Kovács, Alexandra Garafova, Daniela Jezova, Dóra Zelena   +5 more
doaj   +1 more source

Blockade of mineralocorticoid receptor by low-dose spironolactone rescues hypothalamic-ovarian dysfunction in PCOS experimental rat model

Endocrine and Metabolic Science, 2022
Background of study: Studies have shown that women with polycystic ovarian syndrome (PCOS) undergo perturbations of the hypothalamic-pituitary ovarian axis, and frequently suffer from menstrual dysfunction leading to anovulation and infertility ...
Stephanie E. Areleogbe, Mmenyene U. Peter, Adesola A. Oniyide, Christopher O. Akintayo, Adedamola A. Fafure, Mosunmola B. Oyeleke, Isaac O. Ajadi, Oluwatobi A. Amusa, Aturamu Ayodeji, Kehinde S. Olaniyi   +9 more
doaj   +1 more source

Interactions of mineralocorticoids and glucocorticoids in epithelial target tissues [PDF]

, 2000
Interactions of mineralocorticoids and glucocorticoids in epithelial target tissues.BackgroundIn Na+-transporting epithelial target tissues, such as mammalian kidney and the isolated toad bladder, glucocorticoids (GCs) do not normally elicit Na ...
Morris, David J., Brem, Andrew S., Oblin, Marie-Edith, Souness, Graham W.   +3 more
core   +1 more source

Chemical Structure, Classification and Clinical Significance of Steroid Hormones: A Review Article

Al-SalamJournal for Medical Science
Steroid hormones are extremely important in controlling a wide range of body functions. They start from controlling growth before birth and thinking ability and go on to relate to the beginning and development of many illnesses.
Rasha M. Kamil, Zina J. Ghaib
doaj   +1 more source

Abnormality of Aldosterone and Cortisol Late Pathways in Glucocorticoid-Remediable Aldosteronism. [PDF]

, 1994
Patients with glucocorticoid-remediable aldosteronism (GRA) possess a chimeric gene resulting from fusion of the genes encoding steroid aldosterone synthase and 11 beta-hydroxylase.
Boscaro, Marco, Kuhnle, Ursula, KUHNLE U, Fallo, Francesco, Sonino, Nicoletta   +4 more
core   +1 more source

Intestinal Mineralocorticoid Receptor Contributes to Epithelial Sodium Channel–Mediated Intestinal Sodium Absorption and Blood Pressure Regulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Mineralocorticoid receptor (MR) has pathological roles in various cell types, including renal tubule cells, myocytes, and smooth muscle cells; however, the role of MR in intestinal epithelial cells (IECs) has not been sufficiently evaluated ...
Toshifumi Nakamura, Isao Kurihara, Sakiko Kobayashi, Kenichi Yokota, Ayano Murai‐Takeda, Yuko Mitsuishi, Mitsuha Morisaki, Nao Kohata, Yosuke Oshima, Yukiko Minami, Hirotaka Shibata, Hiroshi Itoh   +11 more
doaj   +1 more source

Combination of low-dose glucocorticosteroids and mineralocorticoids as adjunct therapy for adult patients with septic shock: A systematic review and meta-analysis of randomized trials and observational studies

Avicenna Journal of Medicine, 2019
Background: The role of the combination of glucocorticosteroids and mineralocorticosteroids in treating septic shock is not well-defined. The aim of this study was to perform a systematic review and meta-analysis of the randomized controlled trials and ...
Paraschos Archontakis Barakakis, Leonidas Palaiodimos, Derlis Fleitas Sosa, Linda Benes, Perminder Gulani, Daniel Fein   +5 more
doaj   +1 more source

Human DRG Glucocorticoid Receptor Profiling Reveals Targets for Regionally Delivered Steroid Analgesia

Cells
Corticosteroid receptor signaling in primary afferent neurons of the dorsal root ganglion (DRG) has emerged as a potential target to modulate nociception via genomic and nongenomic mechanisms shown in animal pain models. However, the expression landscape
Shaaban A. Mousa, Elsayed Y. Metwally, Xiongjuan Li, Sascha Tafelski, Oscar Andrés Retana Romero, Jörg Piontek, Sascha Treskatsch, Michael Schäfer, Mohammed Shaqura   +8 more
doaj   +1 more source