Научно-практическая ревматология, 2018 Achievement of minimal disease activity (MDA) is the main goal of the Treat-to-target (T2T) strategy in early psoriatic arthritis (ePsA). Radiographic progression in patients with ePsA treated according to the T2T strategy has been studied insufficiently.
E. Yu. Loginova +4 more
doaj +1 more source
DISEASE ACTIVITY IN PATIENTS WITH PSORIATIC ARTHRITIS: A MOLDAVIAN STUDY
Archives of the Balkan Medical Union, 2021 Introduction. Psoriatic arthritis (PsA) is an inflammatory joint disease associated in up to one-third of patients with psoriasis. Studies performed on PsA showed the high burden of the disease, but it still has not been totally quantified due to ...
Tatiana ROTARU +6 more
doaj +1 more source
Arthritis Research & Therapy, 2021 Background In psoriatic arthritis (PsA), further understanding of the relationships between clinical measures and patient-reported outcomes (PROs) is needed.
Laura C. Coates +7 more
doaj +1 more source
Characterising the role of GABA and its metabolism in the wheat pathogen Stagonospora nodorum [PDF]
, 2015 A reverse genetics approach was used to investigate the role of γ-aminobutyric acid metabolism in the wheat pathogenic fungus Stagonospora nodorum. The creation of mutants lacking Sdh1, the gene encoding succinic semialdehyde dehydrogenase, resulted in ...
Mead, Oliver +3 more
core +1 more source
AB0950 Minimal disease activity in real life in psoriatic arthritis [PDF]
Annals of the Rheumatic Diseases, 2018 Background Minimal disease activity (MDA) is an important target in patients with psoriatic arthritis (PsA), however it is also criticised for having low threshold for patient reported outcomes (PRO). Objectives The aim of the study was to assess the prevalence of MDA components in patients with PsA and to evaluate disease characteristics and ...
S.B. Ureyen +10 more
openaire +1 more source
Parallel disease activity of Behçet’s disease with renal and entero involvements: a case report
BMC Nephrology, 2021 Background Behçet’s disease (BD) is a systemic inflammatory vasculitis with both autoimmune and autoinflammatory properties. Renal involvement in BD and its spontaneous remission have been rare.
Kanako Watanabe-Kusunoki +8 more
doaj +1 more source
Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus [PDF]
, 2017 Background: The aim was to assess the attainability and outcome of the lupus low disease activity state (LLDAS) in the early stages of systemic lupus erythematosus (SLE).
CAPPELLAZZO, GIULIA +6 more
core +1 more source
Heterogeneity in Surface Sensing Suggests a Division of Labor in Pseudomonas aeruginosa Populations [PDF]
, 2019 The second messenger signaling molecule cyclic diguanylate monophosphate (c-di-GMP) drives the transition between planktonic and biofilm growth in many bacterial species.
Armbuster, Catherine R. +12 more
core +2 more sources
Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences. [PDF]
, 2020 Hematopoietic stem cell gene therapy is a promising approach for treating disorders of the hematopoietic system. Identifying combinations of cis-regulatory elements that do not impede packaging or transduction efficiency when included in lentiviral ...
Aleshe, Bamidele +14 more
core +1 more source
Научно-практическая ревматология, 2019 Objective: to evaluate the clinical efficacy and safety of the targeted synthetic disease-modifying antirheumatic drug (DMARD) apremilast (AP; Otesla®) in patients with active psoriatic arthritis (PsA) at 14 and 26 weeks after starting the treatment and ...
E. Yu. Loginova +6 more
doaj +1 more source