Results 151 to 160 of about 626,187 (306)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The price of safety and convenience: Urban shoppers' willingness to pay for hygienic market stalls and minimal processing of leafy vegetables in Kenya. [PDF]
PLoS OneMwambi M +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Evaluation of pathogenic bacteria growth and food quality during cold storage in Korean seasoning vegetables subjected to minimal processing. [PDF]
Food Sci BiotechnolHan A, Woo Y, Lee SY.
europepmc +1 more source
Postmodernism, Processing, and the Profession: Towards a Theoretical Reading of Minimal Standars
, 2010 While the ramifications of minimal standards processing for practice are well-documented, the theoretical questions which Greene and Meissner\u27s 2005 article More Product, Less Process raises are not.
Griffin, Melanie
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Developments and opportunities in minimal processing and production of tender jackfruit flour. [PDF]
J Food Sci TechnolPawar DA, Giri SK.
europepmc +1 more source
On Backward Compatibility in GNSS Signal Design
, 2011 This work further develops tools and methodologies for systematic GNSS signal design. Inter and intra system multiple access interference (MAI), synchronization accuracy, time-delay estimation robustness, and backward compatibility with respect to ...
Antreich, Felix +3 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source