Results 31 to 40 of about 6,414,902 (294)

Relationship between minimal residual disease measured by multiparametric flow cytometry prior to allogeneic hematopoietic stem cell transplantation and outcome in children with acute lymphoblastic leukemia

open access: yesHaematologica, 2010
Background The presence of minimal residual disease detected by polymerase chain reaction techniques prior to allogeneic hematopoietic stem cell transplantation has proven to be an independent prognostic factor for poor outcome in children with acute ...
Izaskun Elorza   +5 more
doaj   +1 more source

Metabolic memory underlying minimal residual disease in breast cancer

open access: yesMolecular Systems Biology, 2021
Tumor relapse from treatment‐resistant cells (minimal residual disease, MRD) underlies most breast cancer‐related deaths. Yet, the molecular characteristics defining their malignancy have largely remained elusive.
Ksenija Radic Shechter   +10 more
doaj   +1 more source

Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia [PDF]

open access: yes, 2014
The majority of patients with acute myeloid leukemia (AML) reach complete remission after high-dose chemotherapy. Still, half of these patients experience a relapse due to presence of minimal residual disease (MRD).
van den Ancker, W. (Willemijn)   +12 more
core   +2 more sources

Dynamics of Minimal Residual Disease in Neuroblastoma Patients

open access: yesFrontiers in Oncology, 2019
Neuroblastoma is a common extracranial solid tumor of neural crest (NC) origin that accounts for up to 15% of all pediatric cancer deaths. The disease arises from a transient population of NC cells that undergo an epithelial-mesenchymal transition (EMT ...
Suguru Uemura   +13 more
doaj   +1 more source

Cancer Special Issue: Early detection and minimal residual disease.

open access: yesPLoS Medicine, 2021
Beryne Odeny discusses PLOS Medicine's Special Issue on early cancer detection and minimal residual disease.
Beryne Odeny
doaj   +1 more source

Molecular Minimal Residual Disease in Acute Myeloid Leukemia [PDF]

open access: yes, 2018
BACKGROUND Patients with acute myeloid leukemia (AML) often reach complete remission, but relapse rates remain high. Next-generation sequencing enables the detection of molecular minimal residual disease in virtually every patient, but its clinical ...
Kavelaars, François   +85 more
core   +2 more sources

On computing minimal proper nullspace bases with applications in fault detection [PDF]

open access: yes, 2011
We discuss computationally efficient and numerically reliable algorithms to compute minimal proper nullspace bases of a rational or polynomial matrix.
Andras Varga, Varga, Andreas
core   +1 more source

Cellular dormancy in minimal residual disease following targeted therapy

open access: yesBreast Cancer Research, 2021
Background Breast cancer mortality is principally due to tumor recurrence, which can occur following extended periods of clinical remission that may last decades.
Jason R. Ruth   +11 more
doaj   +1 more source

Flowcytometric and DNA Analysis Minimal Residual Disease (MRD) in Childhood B-Lineage lymphoblastic leukemia [PDF]

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2005
Background: Induction Chemotherapy for Acute Lymphoblastic Leukemia achieves complete remis¬sion in over 90% of children. It is apparent therefore that many patients in clinical remission and with¬out residual disease detectable by conventional light ...
P Vossough   +8 more
doaj   +1 more source

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