Results 81 to 90 of about 656,371 (370)
Haematologica, 2009 Minimal residual disease detection, used for clinical management of children with acute lymphoblastic leukemia, can be performed by molecular analysis of antigen-receptor gene rearrangements or by flow cytometric analysis of aberrant immunophenotypes ...
Julie Irving +16 more
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Minimal Residual Disease Detection in Pediatric Acute Lymphoblastic Leukemia
Clinical Pediatric Hematology-Oncology, 2020 Minimal residual disease (MRD) status is the strongest independent prognostic factor for patients with pediatric acute lymphoblastic leukemia (ALL).
Miyoung Kim, Chan-Jeoung Park
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Haematologica, 2017 Outcome in childhood acute lymphoblastic leukemia is prognosticated from levels of minimal residual disease after remission induction therapy. Higher levels of minimal residual disease are associated with inferior results even with intensification of ...
Owen J. McGinn +6 more
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Advances in Genomic Profiling and Risk Stratification in Acute Myeloid Leukemia. [PDF]
, 2019 OBJECTIVE: To review the current state of molecular and genetic profiling of acute myeloid leukemia (AML) and its implications. DATA SOURCE: Peer-reviewed journal articles.
Coombs, Catherine +3 more
core +1 more source
Artificial Intelligence Enabled Reagent-free Imaging Hematology Analyzer [PDF]
arXiv, 2020 Leukocyte differential test is a widely performed clinical procedure for screening infectious diseases. Existing hematology analyzers require labor-intensive work and a panel of expensive reagents. Here we report an artificial-intelligence enabled reagent-free imaging hematology analyzer (AIRFIHA) modality that can accurately classify subpopulations of
arxiv
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Microfluidics for the detection of minimal residual disease in acute myeloid leukemia patients using circulating leukemic cells selected from blood [PDF]
, 2016 Microfluidic assay for the selection of circulating leukemic cells from peripheral blood for the early detection of minimal residual disease in acute myeloid leukemia ...
Armistead, Paul M. +8 more
core +2 more sources
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Minimal residual disease detection in lymphoma: methods, procedures and clinical significance
Frontiers in ImmunologyLymphoma is a highly heterogeneous lymphohematopoietic tumor. As our understanding of the biological and pathological characteristics of lymphoma improves, we are identifying an increasing number of lymphoma subtypes.
Sijun Zhang +6 more
doaj +1 more source