Results 81 to 90 of about 212,106 (307)
Molecular monitoring and minimal residual disease in the management of chronic myelogenous leukemia [PDF]
, 2014 Michael R. Savona
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Assessment of minimal residual disease in childhood acute lymphoblastic leukemia
Journal of Applied Hematology, 2016 The improving cure rate of childhood acute lymphoblastic leukemia (cALL) is considered as success story in the field of oncology. It has become possible due to progressive refinement of treatment over the period of years.
Sonia K Parikh, Urmila P Uparkar
doaj +1 more source
The CAPRA score versus sub-types of minimal residual disease to predict biochemical failure after external beam radiotherapy [PDF]
, 2020 Nigel P Murray +6 more
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Minimal Residual Disease in Chronic Lymphocytic Leukemia: A New Goal?
Frontiers in Oncology, 2019 In chronic lymphocytic leukemia (CLL), there is a growing interest for minimal residual disease (MRD) monitoring, due to the availability of drug combinations capable of unprecedented complete clinical responses.
Ilaria Del Giudice +11 more
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Minimal Residual Disease in Hematologic Disorders
Archives of Pathology & Laboratory Medicine, 1999 Abstract In almost no other area of medical oncology has the introduction of new drugs, combinations of chemotherapeutic agents, and novel biologic treatments caused such dramatic responses as it has in the treatment of malignant hematologic disorders.
S, Faderl, R, Kurzrock, Z, Estrov
openaire +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Journal of Liquid BiopsyDespite a significant evolution in treatment strategies for early breast cancer (EBC) patients, up to 30% of them experience recurrence due to occult micrometastasis.
Mara S. Serafini +5 more
doaj +1 more source