Results 61 to 70 of about 250,267 (258)

Impact of Anaesthetic Techniques on Minimal Residual Disease, Stress Response, and Recurrence in Breast Cancer: A Comprehensive Review with an Indian Perspective

Journal of Onco-Anaesthesiology and Perioperative Medicine
Breast cancer is the most frequently diagnosed malignancy among women in India. The recurrence after surgical removal and oncotherapy is very important to determine long-term survival.
Samiksha Khanuja, Nazia Nazir, Piyush Bhati   +2 more
doaj   +1 more source

CD20 expression has no prognostic role in Philadelphia-negative B-precursor acute lymphoblastic leukemia: new insights from the molecular study of minimal residual disease

Haematologica, 2012
The prognostic significance of CD20 expression in acute lymphoblastic leukemia has been investigated in children and adults but is still a subject of debate.
Francesco Mannelli, Giacomo Gianfaldoni, Tamara Intermesoli, Chiara Cattaneo, Erika Borlenghi, Sergio Cortelazzo, Irene Cavattoni, Enrico Maria Pogliani, Monica Fumagalli, Emanuele Angelucci, Claudio Romani, Fabio Ciceri, Consuelo Corti, Anna Scattolin, Agostino Cortelezzi, Daniele Mattei, Ernesta Audisio, Orietta Spinelli, Elena Oldani, Alberto Bosi, Alessandro Rambaldi, Renato Bassan   +21 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Development of real-time quantitative polymerase chain reaction assays to track treatment response in retinoid resistant acute promyelocytic leukemia

Frontiers in Oncology, 2011
Molecular detection of minimal residual disease (MRD) has become established to assess remission status and guide therapy in patients with PML-RARA+ acute promyelocytic leukemia (APL).
Jelena V Jovanovic, Kristian eRennie, Dominic eCulligan, Andrew ePeniket, Anne eLennard, Justin eHarrison, Paresh eVyas, Paresh eVyas, David eGrimwade   +8 more
doaj   +1 more source

There is nothing minimal about residual disease [PDF]

Blood, 2018
Can the detection of measurable residual disease (MRD) become the standard approach for acute lymphoblastic leukemia (ALL)? In this issue of Blood,Wood et al1 use a highly sensitive sequencing approach that is an improvement on conventional methods by both performance characteristics and potential for standardization.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Identification of residual leukemic cells by flow cytometry in childhood B-cell precursor acute lymphoblastic leukemia: verification of leukemic state by flow-sorting and molecular/cytogenetic methods

Haematologica, 2012
Reduction in minimal residual disease, measured by real-time quantitative PCR or flow cytometry, predicts prognosis in childhood B-cell precursor acute lymphoblastic leukemia.
Nina F. Øbro, Lars P. Ryder, Hans O. Madsen, Mette K. Andersen, Birgitte Lausen, Henrik Hasle, Kjeld Schmiegelow, Hanne V. Marquart   +7 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Gene rearrangement study for minimal residual disease monitoring in children with acute lymphocytic leukemia

Revista Brasileira de Hematologia e Hemoterapia, 2013
OBJECTIVE To detect markers for minimal residual disease monitoring based on conventional polymerase chain reaction for immunoglobulin, T-cell receptor rearrangements and the Sil-Tal1 deletion in patients with acute lymphocytic leukemia. METHODS Fifty-
Juliana Godoy Assumpcao, Francisco Danilo Ferreira Paula, Sandra Guerra Xavier, Mitiko Murao, Joaquim Caetano de Aguirre Neto, Alvaro Pimenta Dutra, Eduardo Ribeiro Lima, Benigna Maria de Oliveira, Marcos Borato Viana   +8 more
doaj   +1 more source