Results 91 to 100 of about 224,088 (359)

Éduquer dans un monde pluraliste : le minimalisme moral au secours de l’école républicaine ?

Recherches en Éducation, 2014
The moral minimalism is characterized primarily by its reference to a no harm principle (OGIEN, 2007). Is this moral option which seems inherently incompatible with the education, still mobilized in school educational practices? If it is, is it a problem
Vincent Lorius
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Minimal Coding

Annals of Pure and Applied Logic, 1989
It is shown that the real in Jensen's coding theorem can be minimal over the model to be coded. The almost-disjoint forcing part in Jensen's proof is replaced by some kind of perfect set forcing. Before giving the rather involved proof the author gives the special cases when the set to be minimally coded is a subset of \(\omega_ 1\), \(\omega_ 2\), or \
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

From 'scientific revolution' to 'unscientific revolution': an analysis of approaches to the history of generative linguistics [PDF]

, 2010
This paper is devoted to the challenge that generative linguistics poses for linguistic historiography. As a first step, it presents a systematic overview of 19 approaches to the history of generative linguistics.
Aarsleff, Allan, Allan, András Kertész, Anttila, Barsky, Barton, Bierwisch, Boeckx, Butterfield, Chomsky, Chomsky, Chomsky, Chomsky, Chomsky, Chomsky, Chomsky, Chomsky, Chomsky, Chomsky, Chomsky, Droste, Falk, Gray, Grewendorf, Grewendorf, Grewendorf, Griffith, Griffith, Hacken, Hacken, Hacken, Halle, Harris, Harris, Harris, Harris, Hill, Huck, Hymes, Hymes, Izzo, Joseph, Jäger, Jäger, Koerner, Koerner, Koerner, Koerner, Koerner, Koerner, Kuhn, Lakatos, Lakatos, Lakoff, Langendoen, Lappin, Lappin, Lappin, Lees, Leiber, Levine, Maher, Matthews, Matthews, McCawley, McCawley, Murray, Murray, Murray, Murray, Nevin, Newmeyer, Newmeyer, Newmeyer, Newmeyer, Newmeyer, Newmeyer, Newmeyer, Oesterreicher, Percival, Popper, Postal, Pullum, Riemsdijk, Schnelle, Searle, Searle, Seuren, Seuren, Seuren, Seuren, Skinner, Thorne, Tomalin, Trager, Uriagereka, Vidanovič, Voegelin   +98 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Laminated PAINT [PDF]

, 2018
Though we may not perceive it, we are surrounded by material-in-flux. Inert materials degrade and the events that comprise our natural and social environments causally thread into a duration that unifies us in our incomprehension.
Austin, Travis R
core   +1 more source

Minimal Universes

Advances in Mathematics, 1994
An inner model M is MINIMAL if there is a class A such that is amenable yet has no transitive proper elementary submodel. We study minimal universes in the context of 0#. For example we prove: If 0# exists then there is an inner model which is minimal and locally generic over L(i.e., every set in the inner model is set-generic over L).
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Is Meaning Holism Compatible with Semantic Minimalism?

Studia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxi2.04 Meaning Holism and Contextualism are standardly acknowledged to be similar relativistic theories that often lead to similar troubles, in particular to issues concerning instability. On the other hand, the main
Filip Kawczyński
doaj