Results 121 to 130 of about 224,088 (359)

Jüri Okas’ ‘specific objects’: diverging discourses in Estonian Art in the 1970s. [PDF]

open access: yes, 2008
Previously in the University eprints HAIRST pilot service at http://eprints.st-andrews.ac.uk/archive/00000367/Article 3 of 6 in issue devoted to the visual culture of the Scandinavian and Baltic region.This article will look at the early works of ...
Kurg, Andres.
core  

Minimal R_1, minimal regular and minimal presober topologies

open access: yes, 2013
By means of filters, minimal R_1 and minimal regular topologies are characterized on suitable intervals consisting of non-trivial R_0 topologies.
Colasante, Maria Luisa   +1 more
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Minimalism and Speakers’ Intuitions

open access: yesIdeas y Valores, 2011
Minimalism proposes a semantics that does not account for speakers’ intuitions about the truth conditions of a range of sentences or utterances. Thus, a challenge for this view is to offer an explanation of how its assignment of semantic contents to ...
Matías Gariazzo
doaj   +2 more sources

ISO and Social Standardisation: Uncomfortable compromises in Global Policy-Making [PDF]

open access: yes, 2011
This paper intends to explore the involvement of ISO, the world’s most iconic standard-setting institution, in the field of social responsibility, leading to the publication of the ISO26000 standard in November, 2010.
Peña, A. M.
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Fragility of democratic minimalism: why the ballot is insufficient for democracy

open access: yesFrontiers in Political Science
This paper engages Hamid's democratic minimalism which proposes democracy via ballot form is not only necessary but sufficient for democracy to flourish. Hamid proposes a state sustaining democratic norms such as voting, free elections, and protection of
Sam Mace
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Minimal intervention [PDF]

open access: yesBritish Dental Journal, 2004
R F, Mosedale, F J T, Burke
openaire   +2 more sources

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