Results 81 to 90 of about 366,214 (267)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Video-based assistance system for training in minimally invasive surgery

, 2010
In this paper, the development of an assisting system for laparoscopic surgical training is presented. With this system, we expect to facilitate the training process at the first stages of training in laparoscopic surgery and to contribute to an ...
Moreno del Pozo, Jose, Juan A. Sánchez-Margallo, Enrique J. Gómez, José B. Pagador, Jesús Usón, Blas Pagador, Jose, Gómez Aguilera, Enrique J., Sánchez Margallo, Juan Alberto, Uson Gargallo, Jesús, Patricia Sánchez-González, Sánchez Margallo, Francisco Miguel, José Moreno, Sánchez González, Patricia, Francisco M. Sánchez-Margallo   +13 more
core   +1 more source

Sorafenib Combined with Tislelizumab and Transarterial Chemoembolization for Advanced-Stage Hepatocellular Carcinoma: A Phase II Study

ImmunoTargets and Therapy
Licong Liang,1,2,* Jingwen Zhou,1,2,* Jingjun Huang,1,2,* Yongjian Guo,1,2 Zhimei Zhou,2,3 Ye Chen,1,2 Liteng Lin,1,2 Xiaoyang Hong,1,4 Wenbo Shi,1,5 Zhaoyi Lin,1,2 Juan Liu,1,2 Kangshun Zhu,1,2 Wensou Huang,1,2 Mingyue Cai1,2 ...
Liang L, Zhou J, Huang J, Guo Y, Zhou Z, Chen Y, Lin L, Hong X, Shi W, Lin Z, Liu J, Zhu K, Huang W, Cai M   +13 more
doaj  

Laparoscopic Pancreaticoduodenectomy After Roux-en-Y Gastric Bypass: Case Report and Literature Review

Case Reports in Surgery
This is a case report of an alternate laparoscopic reconstruction possibility in a patient that required a cephalic duodenopancreatectomy (DPC) who previously underwent a Roux-en-Y gastric bypass (RYGB).
Makai-Popa Silviu-Tiberiu, De Blasi Vito, Moga Marius Alexandru, Arru Luca, Goergen Martine, Azagra Juan Santiago   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Percutaneous Iliac Screws for Minimally Invasive Spinal Deformity Surgery [PDF]

, 2012
Introduction . Adult spinal deformity (ASD) surgeries carry significant morbidity, and this has led many surgeons to apply minimally invasive surgery (MIS) techniques to reduce the blood loss, infections, and other peri-operative complications.
Wang, Michael Y
core   +1 more source

Minimally Invasive Lateral Access Corpectomy for a Solitary Renal Cell Carcinoma Spinal Metastasis: A Case Report

, 2021
10.21182/jmisst.2018.00360Journal of Minimally Invasive Spine Surgery and Technique3270 ...
Hung, Wu Pang, Zhao Jie, Joel Lee, Gamaliel, Tan Yu Heng   +2 more
core   +1 more source

Soft skills during residency in Spain: an analysis of the specialized training programmes

BMC Medical Education
Background In recent years, the importance of soft skills in reducing errors and consequently improving clinical practice has become increasingly evident. Residents should be trained in these skills during their specialised training.
Luisa F. Sánchez-Peralta, J. Blas Pagador, Francisco M. Sánchez Margallo   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source