Results 101 to 110 of about 439,248 (349)

Traditional Biocidal Replacement Viability of Microcrystalline Silver Chloride [PDF]

, 2017
The antimicrobial effects of silver ions and silver chloride nanoparticles have been well established while the efficacy of microcrystalline silver chloride has been less studied.
Curtis, R., Hemminger, Zachary, Picardo, Kristin F., Walsh, P.   +3 more
core   +1 more source

Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]

, 2015
Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne, Ahmad, Amais, Christiansen, Lasse Engbo, Damborg, Peter, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +9 more
core   +4 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Inhibitory Efficacy of Thymus vulgaris and Origanum onites Essential Oils on Enterococcus faecalis Biofilm

Bezmiâlem Science
Objective: The crucial aim of irrigation solutions used in root canal treatments is the elimination of biofilm which is considered an important virulence factor of Enterococcusfaecalis.
Didem SAKARYALI UYAR, Aylin ÜSKÜDAR GÜÇLÜ   +1 more
doaj   +1 more source

Novel FR-900493 Analogues That Inhibit the Outgrowth of Clostridium difficile Spores [PDF]

, 2018
The spectrum of antibacterial activity for the nucleoside antibiotic FR-900493 (1) can be extended by chemical modifications. We have generated a small focused library based on the structure of 1 and identified UT-17415 (9), UT-17455 (10), UT-17460 (11),
Clemons, William M., Jr., Eslamimehr, Shakiba, Klaić, Lada, Kurosu, Michio, Kurosu, Sara M., Lemieux, Maddie R., Mitachi, Katsuhiko, Yun, Hyun Gi   +7 more
core   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Staphylococcus epidermidis biofilms control by N-acetylcysteine and rifampicin [PDF]

, 2013
Medical device-associated infections caused by Staphylococcus epidermidis usually involve biofilm formation and its eradication is particularly challenging.
Gomes, F. I., Leite, Bruna, Oliveira, Rosário, Pizzolitto, Elisabeth, Souza, Clovis, Teixeira, P.   +5 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Discordance in genotypic and phenotypic drug susceptibility results: time to reconsider critical concentration of rifampicin

Microbiology Spectrum
The objective of this study is to correlate rpoB mutations found on the new-generation sequencing (NGS) in Mycobacterium tuberculosis (MTB) isolates with minimum inhibitory concentrations (MICs) to the rifampicin (RIF). We assessed the minimum inhibitory
Arti Shrivas, Sarman Singh, Jitendra Singh, Prem Shankar, Payal Soni, Syed Beenish Rufai, Anand Maurya, Shashank Purwar   +7 more
doaj   +1 more source

Additional file 1 of Using random forest to predict antimicrobial minimum inhibitory concentrations of nontyphoidal Salmonella in Taiwan

, 2023
Chia‐Chi Wang, Yu-Ting Hung, Che-Yu Chou, Shih‐Ling Hsuan, Zeng-Weng Chen, Pei-Yu Chang, Tong‐Rong Jan, Chun-Wei Tung   +7 more
openalex   +1 more source