Results 61 to 70 of about 439,248 (349)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The pet industry is currently expanding and specializing mainly in the field of domestic felines. Problems related to antimicrobial resistance are frequent, and the use of essential oils (EOs) in animal feed has become a novel treatment strategy.
Monique Catarine Fischer Possamai +9 more
doaj +1 more source
Water is an essential resource and its purity should not be negotiated when it comes to human consumption. This study investigated the antibacterial activity of Garcinia kola and Hunteria umbellata seed and epicarp on some bacterial isolates from sachet ...
Tosan Mercy AKIRI-OBAROAKPO +2 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
bjective: The purpose of this study was to determine the exact values of MBC (Minimum Bactericidal Concentration) and MIC (Minimum Inhibitory Concentration) of beluntas leaf extract against Streptococcus mutans colonies. Material and Methood: This study used Streptococcus mutans ATCC 25175 and ethanol extract of beluntas leaves with ...
Elin Septiani +2 more
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The In vitro Study of Antimicrobial Effect of Teucrium polium Extract on Infectious Microorganisms
Introduction & Objective: Teucrium polium belonging to Lamiaceae family has been widely used in traditional medicine for treatment of diseases. Regarding the existence of the active biological compounds in this plant, it seems that this plant has ...
Farideh Tabatabaei Yazdi +3 more
doaj
Background: Recent years have seen an alarming rise in the prevalence of recalcitrant and relapsing dermatophyte infections in India associated with lack of clinical response to standard antifungal regimens. Aims and Objectives: A study was undertaken to
Shital Poojary +4 more
doaj +1 more source
Antibacterial Activity of Homoeopathic Tinctures on Bacterial Strains of Streptococcus mutans and Enterococcus faecalis: An In vitro Study [PDF]
Introduction: In view of increasing resistance to existing antimicrobial agents herbal drugs are being looked as very important source for discovery of new agents for treating various ailments related to bacterial infections. Hypericum perforatum, Arnica
Viraj Satish Yalgi, Kishor Gajanan Bhat
doaj +1 more source
Inhibitory Activity Of Zingiber Officinale Var Rubrum Extract Against Staphylococcus Aureus [PDF]
Background: gram-negative bacteria-salmonella typhi and gram-positive bacteria-staphylococcus aureus are types of bacteria that cause infectious disease among several areas in Indonesia. Staphylococcus aureus often found in skin lesions injury.
Dewi, F. I. (Firnanda) +1 more
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