Results 131 to 140 of about 4,684 (179)

Biology and Applications of Human Minisatellite Loci

Current Opinion in Genetics and Development, 1992
Highly repetitive minisatellites' include the most variable human loci described to date. They have proved invaluable in a wide variety of genetic analyses, and despite some controversies surrounding their practical implementation, have been extensively adopted in civil and forensic casework.
John A.L. Armour, J A Armour
exaly   +3 more sources

A fungal minisatellite

Nature, 1997
Genetik, genomics, molekylærbiologi, molekylær ...
Andersen, Thomas Henrik, Nilsson-Tillgren, Nils Torsten   +1 more
openaire   +3 more sources

A pseudoautosomal minisatellite in the pig

Mammalian Genome, 1994
72656
SIGNER, EN, GU, F, GUSTAVSSON, I, ANDERSSON, L, JEFFREYS, AJ   +4 more
openaire   +3 more sources

Minisatellite variant repeat (MVR) analysis of the HRAS1 minisatellite locus

ELECTROPHORESIS, 1998
AbstractTwo alternative electrophoretic strategies were used to study the internal variation of the HRAS1 minisatellite after minisatellite variant repeat mapping (MVR‐PCR) was carried out. While the use of automated sequencers with fluorescent based technology is ideal for analyzing fragment size, and therefore, for analyzing the repeat number, the ...
A, Vega, F, Barros, S, Bellas, A, Carracedo   +3 more
openaire   +2 more sources

Heteroduplex analysis of minisatellite variability

ELECTROPHORESIS, 2005
AbstractMinisatellites are tandem repeat arrays of middle size (5–100 bp) repeat units widely distributed in eukaryotic genomes. They have been related to several important features of human genome biology, including gene regulation, chromosomal fragile sites, and imprinting.
Paula, Barros, Miguel G, Blanco, Francisco, Boán, Jaime, Gómez-Márquez   +3 more
openaire   +2 more sources

Minisatellites of the Y Chromosome

1994
In recent years, the use of VNTR polymorphisms has became one of the most successful changes in the field of forensic medicine for personal identification and paternity testing. VNTR sequences have been identified on all human chromosomes and usually they map at or close to the telomers (1).
FATTORINI, PAOLO, FLORIAN, FIORELLA, VATTA M, COSSUTTA F, DE CRISTINI F, ALTAMURA B. M, GRAZIOSI G.   +6 more
openaire   +2 more sources

Mutation processes at human minisatellites

ELECTROPHORESIS, 1995
AbstractMinisatellites provide one of the most experimentally tractable systems for studying tandem repeat instability in man. Analysis of mutation processes has been greatly aided by the development of single molecule methods for recovering de novo mutants, and of techniques for exploring allele structure in detail.
JEFFREYS, AJ, ALLEN, MJ, ARMOUR, JAL, COLLICK, A, DUBROVA, Y, FRETWELL, N, GURAM, T, JOBLING, M, MAY, CA, NEIL, DL, NEUMANN, R   +10 more
openaire   +3 more sources

Spontaneous and induced minisatellite instability

ELECTROPHORESIS, 1997
AbstractMinisatellites provide not only the basis for DNA fingerprinting and DNA profiling but also extremely informative systems for analysing processes of tandem repeat turnover in the human genome. Minisatellite instability appears to involve distinct mutation processes in somatic and germline cells; in the germline, mutation is frequently dominated
Jeffreys, AJ, Bois, P, Buard, J, Collick, A, Dubrova, Y, Hollies, CR, May, CA, Murray, J, Neil, DL, Neumann, R, Stead, JD, Tamaki, K, Yardley, J   +12 more
openaire   +3 more sources

Minisatellite mapping in manic depression

Journal of Psychiatric Research, 1987
Hypervariable regions of DNA exist at many discrete loci in the human genome. Variations in the length of specific classes of hypervariable DNA termed "minisatellite" sequences may be detected by hybridisation of radioactive probes composed of a common 10-15 base pair repeat or "core" sequence which is shared by each of the minisatellite loci.
S, Hodgkinson, H M, Gurling, R H, Marchbanks, M, McInnis, H, Petursson   +4 more
openaire   +2 more sources

Biological significance of minisatellites

ELECTROPHORESIS, 1995
AbstractMinisatellites are tandemly repeated, highly variable DNA sequences found in most higher eukaryotes. These contain a core sequence resembling the chi sequence of Escherichia coli, which is a binding site for recombination proteins. Based on this, a generalized function of minisatellites to provide binding sites for recombination proteins in ...
openaire   +2 more sources