Results 11 to 20 of about 1,625 (152)

Preparation and pharmacological effects of minor ginsenoside nanoparticles: a review

Frontiers in Pharmacology, 2022
Ginseng (Panax ginseng) is a perennial herbaceous plant belonging to Panax genus of Araliaceae. Ginsenosides are a kind of important compounds in ginseng and minor ginsenosides are secondary metabolic derivatives of ginsenosides.
Yue Ke, Lei Huang, Yu Song, Zhenxin Liu, Linshuang Liang, Linmao Wang, Taoyun Wang   +6 more
doaj   +3 more sources

Production of Minor Ginsenoside CK from Major Ginsenosides by Biotransformation and Its Advances in Targeted Delivery to Tumor Tissues Using Nanoformulations

Nanomaterials, 2022
For over 2000 years, ginseng (roots of Panax ginseng C.A. Meyer) has been used as a traditional herbal medicine. Ginsenosides are bioactive compounds present in ginseng responsible for the pharmacological effects and curing various acute diseases as well
Mohanapriya Murugesan, Ramya Mathiyalagan, Vinothini Boopathi, Byoung Man Kong, Sung-Keun Choi, Chang-Soon Lee, Deok Chun Yang, Se Chan Kang, Thavasyappan Thambi   +8 more
doaj   +3 more sources

Minor ginsenoside F1 improves memory in APP/PS1 mice [PDF]

Molecular Brain, 2019
Ginseng has been shown to produce a cognitive improvement effect. The key molecular components in ginseng that produce pharmacological effects are ginsenosides. Previous studies reported a memory improvement effect of a few major ginsenosides.
Junho Han, Jung-Pyo Oh, Miran Yoo, Chang-Hao Cui, Byeong-Min Jeon, Sun-Chang Kim, Jin-Hee Han   +6 more
doaj   +3 more sources

Microbial conversion of major ginsenosides in ginseng total saponins by Platycodon grandiflorum endophytes

Journal of Ginseng Research, 2016
Background: In this study, we screened and identified an endophyte JG09 having strong biocatalytic activity for ginsenosides from Platycodon grandiflorum, converted ginseng total saponins and ginsenoside monomers, determined the source of minor ...
Lei Cui, Song-quan Wu, Cheng-ai Zhao, Cheng-ri Yin   +3 more
doaj   +3 more sources

Comparison of the Transformation Ability of the Major Saponins in Panax notoginseng by Penicillum fimorum Enzyme and Commercial β-glucosidase [PDF]

Microorganisms
Ginsenosides with less sugar groups, which are called minor ginsenosides, might have a greater pharmacological activity and better adsorptive ability, but their content in nature is extremely low.
Feixing Li, Ruixue Zhang, Dongmei Lin, Jin Yang, Ye Yang, Xiuming Cui, Xiaoyan Yang   +6 more
doaj   +2 more sources

High-density immobilization of a ginsenoside-transforming β-glucosidase for enhanced food-grade production of minor ginsenosides. [PDF]

Appl Microbiol Biotechnol, 2019
Use of recombinant glycosidases is a promising approach for the production of minor ginsenosides, e.g., Compound K (CK) and F1, which have potential applications in the food industry. However, application of these recombinant enzymes for food-grade preparation of minor ginsenosides are limited by the lack of suitable expression hosts and low ...
Cui CH, Jeon BM, Fu Y, Im WT, Kim SC.
europepmc   +9 more sources

Heat Treatment Enhances the Neuroprotective Effects of Crude Ginseng Saponin by Increasing Minor Ginsenosides. [PDF]

Int J Mol Sci, 2023
Abstract Ginsenoside is the primary active substance of ginseng and has many pharmacological effects, such as anti-cancer, immune- sugar- and lipid metabolism-regulating, and antioxidant effects. It also protects the nervous and cardiovascular systems.
Ji YJ, Kim HD, Lee ES, Jang GY, Seong HA.   +4 more
europepmc   +3 more sources

Highly Regioselective Biotransformation of Protopanaxadiol-type and Protopanaxatriol-type Ginsenosides in the Underground Parts of Panax notoginseng to 18 Minor Ginsenosides by Talaromyces flavus. [PDF]

ACS Omega, 2022
The transformation of major ginsenosides to minor ginsenosides by microorganisms was considered to be an environmentally friendly method. Compared with GRAS (generally recognized as safe) strains, non-food-grade microorganisms could transform polar ginsenosides to various minor ginsenosides.
Liang YZ, Guo M, Li YF, Shao LJ, Cui XM, Yang XY.   +5 more
europepmc   +3 more sources

The potential of minor ginsenosides isolated from the leaves of Panax ginseng as inhibitors of melanogenesis. [PDF]

Int J Mol Sci, 2015
Three minor ginsenosides, namely, ginsenoside Rh6 (1), vina-ginsenoside R4 (2) and vina-ginsenoside R13 (3), were isolated from the leaves of hydroponic Panax ginseng. The chemical structures were determined based on spectroscopic methods, including fast atom bombardment mass spectroscopy (FAB-MS), 1D-nuclear magnetic resonance (NMR), 2D-NMR, and ...
Lee DY, Cha BJ, Lee YS, Kim GS, Noh HJ, Kim SY, Kang HC, Kim JH, Baek NI.   +8 more
europepmc   +5 more sources

Effects of Minor Ginsenosides, Ginsenoside Metabolites, and Ginsenoside Epimers on the Growth of Caenorhabditis elegans. [PDF]

J Ginseng Res, 2011
In the previous report, we have demonstrated that ginsenoside Rc, one of major ginsenosides, is a major component for the restoration for normal growth of worms in cholesterol-deprived medium. In the present study, we further investigated the roles of minor ginsenosides, such as ginsenoside Rh1 and Rh2, ginsenoside metabolites such as compound K (CK ...
Lee JH, Ahn JY, Shin TJ, Choi SH, Lee BH, Hwang SH, Kang J, Kim HJ, Park CW, Nah SY.   +9 more
europepmc   +4 more sources