Results 101 to 110 of about 205 (161)
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
PROTEOMICS, Volume 26, Issue 8, Page 9-28, August 2026.ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Post‐Translational Isoaspartate Promotes Amyloid Formation in β2‐Microglobulin
Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.Chemical synthesis of five β2‐microglobulin (β2m) variants reveals the structural impact of Asn deamidation. By introducing Asp or isoAsp at susceptible Asn‐Gly sequences, we demonstrate that isoAsp17 formation specifically accelerates amyloid fibril formation, highlighting its potential contribution to dialysis‐related amyloidosis.
Ryuji Kawakami +5 more
wiley +2 more sources
Engineered Bacterial Membranes as Next‐Generation Platforms for Cancer Immunotherapy
Small Science, Volume 6, Issue 8, August 2026.Engineered bacterial membrane platforms, including outer membrane vesicles, bacterial ghosts, genetically engineered membranes, and hybrid bacterial–tumor membranes, integrate tumor antigen presentation with intrinsic immune stimulation. These platforms promote dendritic‐cell activation, T‐cell priming, pyroptosis, and synergistic responses with ...
Hafiza Aasia Malik +4 more
wiley +1 more source
Oligoprogressive renal cell carcinoma: What is the role of surgery?
BJU International, Volume 138, Issue 2, Page 219-228, August 2026.Objective To provide an overview of the biological mechanism and pattern of oligoprogression in renal cell carcinoma (RCC) and the most updated role of surgery in this setting, highlighting scientific gaps and informing future implications. Methods A non‐systematic search of PubMed/MEDLINE was performed in August 2025 including guidelines, reviews, and
Chiara Re +9 more
wiley +1 more source
Cell Proliferation, Volume 59, Issue 8, August 2026.This multi‐omics study reveals the significant role of MAIT cells in liver transplant rejection. MAIT cells drive rejection in liver transplantation via the MR1 axis. Their absence reshapes T cell responses and clonal expansion, attenuating allograft injury.
Hailun Cai +15 more
wiley +1 more source
ROLE OF POLYMORPHISM FOR THE PANE1 GENE IN THE FORMATION OF REPRODUCTIVE INDICES IN PIGS
Вавиловский журнал генетики и селекции, 2015 A tradeoff between reproductive success and immunity is observed in wild and laboratory animals owing to limited energy resources of an organism. Therefore, artificial selection of farm animals for reproductive indices may be accompanied by reduced ...
N. S. Yudin +6 more
doaj
European Journal of Haematology, Volume 117, Issue 2, Page 320-337, August 2026.ABSTRACT Minimal residual disease (MRD) has emerged as a central biomarker in hematologic malignancies, enabling highly sensitive detection of tumor persistence beyond conventional morphologic assessment and serving as an increasingly important surrogate endpoint in clinical trials.
Santino Caserta +14 more
wiley +1 more source
Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
Experimental Physiology, Volume 111, Issue 8, Page 3843-3856, 1 August 2026.Abstract Antigen‐processing and ‐presenting cells play a pivotal role in initiation of the antiviral immune response. The cellular adaption of dendritic cells to reduced oxygen and nutrition levels at the site of infection is regulated predominantly by the transcription factor complex hypoxia‐inducible factor‐1 (HIF‐1).
Timm Schreiber +8 more
wiley +1 more source