Results 181 to 190 of about 44,254 (226)
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Much ado about minor histocompatibility antigens
Immunology Today, 1998Abstract Current knowledge of histocompatibility (H) loci located outside of the major histocompatibility complex - i.e. those encoding the so-called minor H antigens - was surveyed at a recent meeting ∗ ∗The 1st International Symposium on Minor Histocompatibility Antigens was held at Bar Harbor, ME, USA, on 14–17 September 1997..
Simpson, E, Roopenian, D, Goulmy, E
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Minor Histocompatibility Antigens and Marrow Transplantation
New England Journal of Medicine, 1996Acute graft-versus-host disease (GVHD) and graft rejection are the principal obstacles to successful allogeneic bone marrow transplantation.
N A, Kernan, B, Dupont
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Minor histocompatibility antigens – big in tumour therapy
Trends in Immunology, 2004Technical advances combined with the deciphering of the human genome have facilitated the identification of the molecular nature of human minor histocompatibility (H) antigens. To date, it is believed that minor H antigens result from just any polymorphic protein, regardless of their functional properties.
Spierings, E. +2 more
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The genetic origin of minor histocompatibility antigens
Immunogenetics, 1993The purpose of this study was to elucidate the genetic origin of minor histocompatibility (H) antigens. Toward this end common inbred mouse strains, distinct subspecies, and species of the subgenus Mus were examined for expression of various minor H antigens.
Roopenian, D C +4 more
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Immunodominant minor histocompatibility antigens: the major ones
Immunology Today, 1998Abstract Minor histocompatibility antigens (MiHAs) are extremely numerous—possibly up to 720 in mice—and have been regarded as an `immunogenetic nightmare' in transplantation. Here, Claude Perreault, Denis Roy and Claudette Fortin summarize evidence showing that most anti-MiHA T-cell responses are oligoclonal, being restricted to several dominant ...
C, Perreault, D C, Roy, C, Fortin
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Antigenic competition between minor (Non-H-2) histocompatibility antigens
Immunogenetics, 1981The potential for interactions between different antigens in grafted tissue is important, for practical reasons, to the transplant surgeon. In addition, these interactions can provide the immunologist with an insight into complex cellmediated immune responses. Minor histocompatibility antigens are both useful and convenient for experimental examination
Johnson, L L +2 more
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Minor Histocompatibility Antigens
The Cancer Journal, 2004Minor histocompatibility antigens have to be considered as key molecules in the stem cell-based immunotherapy of malignancies. Allogeneic stem cell transplantation (SCT) is a well-established and effective therapy for advanced hematologic malignancies.
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Clinical relevance of minor histocompatibility antigens
Leukemia Research, 2019Conference Conference: 10th Eurasian Hematology Oncology Congress Location: Istanbul, TURKEY Date: OCT 08-11 ...
Savran Oğuz, Fatma +4 more
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Molecular Typing Methods for Minor Histocompatibility Antigens
2007Minor histocompatibility (H) antigens crucially affect the outcome of human leukocyte antigen-matched allogeneic stem cell transplantation. The number of molecularly identified minor H antigens is rapidly increasing. In parallel, clinical implementation of minor H antigens for immunotherapy has gained significant interest.
Eric, Spierings, Els, Goulmy
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Tregs Specific for Minor Histocompatibility Antigens
Blood, 2012Abstract Abstract 1891 Background: The risk of acute GVHD after HSCT is increased in male recipients of female grafts. Disparities for the male-associated H-Y and other minor histocompatibility antigens (mHAs) have the capacity to sensitize alloreactive donor T cells and cause GVHD in ...
Anandharaman Veerapathran +5 more
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