Results 171 to 180 of about 23,101 (249)

Definition of the Gene Encoding the Minor Histocompatibility Antigen Ha-1 and Typing for Ha-1 from Genomic DNA

open access: yes, 2009
Recipient mismatching for the minor histocompatibility antigen HA-1 has been associated with acute graft-versus- host disease after allogeneic marrow transplantation.
曾麗慧;林敏哲   +1 more
core  

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

High frequencies of cytotoxic T cell precursors against minor histocompatibility antigens after HLA-identical BMT: absence of correlation with GVHD

open access: yes, 1993
Limiting dilution analysis was used to quantify the frequency of cytotoxic T cell precursors (CTLp) against minor histocompatibility (H) antigens induced by HLA-identical BMT.
Bontkes, H   +4 more
core  

Dynamic Immune Reconstitution and Clinical Outcomes of Three Different Protocols for Haploidentical Hematopoietic Stem Cell Transplantation

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This study compared clinical outcomes and immune reconstitution in haplo‐HSCT patients receiving PTCY (n = 45), ATG (n = 45), or PTCY+ATG (n = 45). The ATG group had superior OS (p = 0.029) and LFS (p = 0.034), with higher CD3+ and CD8+ T‐cell counts at 3 months.
Xiao‐Di Ma   +11 more
wiley   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang   +8 more
wiley   +1 more source

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu   +3 more
wiley   +1 more source

The Tumor Immune Microenvironment in Endometrial Cancer: Composition, Molecular Subtypes, and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Endometrial cancer (EC), a major gynecologic malignancy and a representative “cold tumor”, exhibits a tumor immune microenvironment (TIME) influenced by a broad range of cellular and molecular elements, immunosuppressive signals, and pathways of immune evasion.
Jingxuan Ye   +4 more
wiley   +1 more source

Current Status of Kidney Xenotransplantation in Basic Research

open access: yesOrgan Medicine, Volume 3, Issue 2, Page 87-101, June 2026.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Effects of selective harvest on antler size of white‐tailed deer in Texas, USA

open access: yesWildlife Monographs, Volume 222, Issue 1, June 2026.
We conducted 20 years of experiments on the selective harvest of white‐tailed deer by antler size, judged inferior, in 2 areas of South Texas, USA. Selective harvest increased the phenotypic antler size of older males in one study area but not the other. There was little evidence of evolution resulting from selective harvesting. Abstract There has been
Don A. Draeger   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy