Results 181 to 190 of about 23,101 (249)
Aging Cell, Volume 25, Issue 6, June 2026.Aging impairs vaccine efficacy through gut microbiota dysbiosis and mTOR hyperactivation, which together drive inflammaging and weaken immune memory. This review highlights the bidirectional microbiota–mTOR axis and proposes that combining mTOR inhibitors with microbiota modulation offers a promising strategy to enhance vaccine responses in older ...
Jiaxuan Li +5 more
wiley +1 more source
Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side
Allergy, Volume 81, Issue 6, Page 1985-2000, June 2026.ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm +9 more
wiley +1 more source
Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle
Evolutionary Applications, Volume 19, Issue 6, June 2026.ABSTRACT Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease. In this respect, integrative genomics, leveraging population and functional genomic data, can be employed to ...
Gillian P. McHugo +10 more
wiley +1 more source
Don't Cut the Cord: Why Umbilical Cord Blood Still Deserves a Place in Transplantation
International Journal of Immunogenetics, Volume 53, Issue 3, Page 229-239, June 2026.ABSTRACT The use of umbilical cord blood (UCB) as a stem cell source in haematopoietic stem cell transplant (HSCT) has greatly declined in recent years. It has largely been replaced by mismatched unrelated and family donors, facilitated by advances in transplant technologies, including post‐transplant cyclophosphamide to prevent graft‐versus‐host ...
Jenna Nunn, Kay Poulton, Robert Wynn
wiley +1 more source
Induction of Clinical Operational Tolerance Through Immunosuppression Minimization: Less Is More?
Liver International, Volume 46, Issue 6, June 2026.ABSTRACT The goal of achieving clinical operational tolerance in liver transplantation has sparked significant interest, driven by the desire to mitigate the long‐term adverse effects of immunosuppression. Advances in understanding the immunological mechanisms underpinning operational tolerance in liver transplantation have highlighted the central role
Emilia Knioła +4 more
wiley +1 more source
The TCXpress lane to T-cell receptor-engineered T cells. [PDF]
Blood AdvBiernacki MA.
europepmc +1 more source
Vox Sanguinis, Volume 121, Issue 6, Page 710-721, June 2026.Abstract Background and Objectives Adequate representation of donors from diverse ancestral populations in blood, stem cell and organ transplantation is critical to ensuring equitable access to these lifesaving therapies. Because of population‐level differences in genetic markers, patients from racialized groups may have unique transfusion and ...
Bonnie Lu +9 more
wiley +1 more source
Occurrence and Impact of Minor Histocompatibility Antigens' Disparities on Outcomes of Hematopoietic Stem Cell Transplantation from HLA-Matched Sibling Donors. [PDF]
Bone Marrow Res, 2012 Dzierzak-Mietla M +7 more
europepmc +1 more source
Optimal donor selection for transplant to reduce GVHD risk and augment graft-versus-malignancy efficacy. [PDF]
Curr Opin ImmunolShaffer BC, Shaw BE.
europepmc +1 more source