Results 61 to 70 of about 13,589 (276)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
"Bonshommes”, (the “new people”) and the pre-communal “conspiracy”. XI-XII Centuries
Montesquieu.it, 2018 In the crisis of the ancient political and ecclesiastical orders, which represented a true crisis in the legitimacy of the traditional authorities (Regnum e Sacerdotium fighting for universal supremacy), a profound and dramatic crisis for the medieval ...
Rita Bellelli
doaj +1 more source
"Terrae motus factus est”: earthquakes in Switzerland before A.D. 1000. A critical approach [PDF]
, 2018 We focus on Swiss earthquakes in antiquity and the early medieval period before A.D. 1000. We have information on less than half a dozen earthquakes within this era, since written records for the first half of the first millennium A.D.
Fäh, Donat +2 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Nouvelle Revue Synergies Canada, 2022 Les mobilisations pour les droits des étrangers sont parfois le cadre de pratiques langagières reposant sur une idéologie langagière caractérisant la parole politique comme une voie d’émancipation possible. On s’intéressera en particulier à une pratique,
Marie Veniard
doaj
El Beato Ramón Llull en sus relaciones con la Escuela Franciscana de los siglos XIII-XIV [PDF]
, 1965 not ...
Oliver, Antonio
core +6 more sources
Regional Enlightenment in Transylvania: The educational reforms of Bishop Petru Pavel Aron, their influences and effects on the Uniate society in Transylvania in the Age of Enlightenment [PDF]
, 2015 The Transylvanian Enlightenment is a very contained phenomenon, yet fully fledged, attributed to a group of intellectuals in the last two decades of the eighteenth century known as the Transylvanian School.
Florutau, MI
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source