Results 81 to 90 of about 13,589 (276)

Historical objections against the number line [PDF]

open access: yes, 2011
Historical studies on the development of mathematical concepts will help mathematics teachers to relate their students’ difficulties in understanding to conceptual problems in the history of mathematics.
Heeffer, Albrecht
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Franz von Assisi und die Diakonie [PDF]

open access: yes, 2003
Diakonie ist in der Zeit des hl. Franz in Assisi sowohl in ritueller als auch in materieller Hinsicht wohlorganisiert. Er selbst übt sich vor seiner Konversion in der einem frommen Katholiken üblichen Barmherzigkeit.
Weber, Edmund
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Escandaloso, ofensivo y malsonante. Censura y vigilancia de la prosa espiritual en la España del Siglo de Oro

open access: yesCriticón, 2014
This article proposes a first approach to uses and meanings of scandal in the Golden Age, understood here as a specific type of heterodoxy, a form of dissent, one of the categories of propositiones damnabiles and hence an instrument of censorship that ...
María José Vega
doaj   +1 more source

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Starania wrocławskiego Kościoła o uzyskanie swobody gospodarczej i sądowej na swych dobrach w I poł. XIII wieku – umowa z 1249 r.

open access: yesWrocławski Przegląd Teologiczny, 2013
By the end of the twelfth century the bishopric of Wrocław owned a lot of goods and become a major economic power, although it was not sovereign against princely power. On the lands, which were granted to the Bishop, were goods belonging to the prince or
Norbert Jerzak
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Minority within Minorities

open access: yes
The chapter is a contribution towards the discourse on gender and power in the context of Nambya women in Hwange district in Zimbabwe, who have suffered from multiple marginalisation due to their cultural practices, ethnicity and gender. Of significance are the cultural practices embedded in marriage, ritual practices and family dynamics which are ...
openaire   +1 more source

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