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Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska +14 more
wiley +1 more source
A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
The Role of Hypoxia-Induced miR-210 in Cancer Progression [PDF]
Prolonged hypoxia, the event of insufficient oxygen, is known to upregulate tumor development and growth by promoting the formation of a neoplastic environment.
Dang, K, Myers, KA
exaly +3 more sources
miR‐210: More than a silent player in hypoxia
Multiple studies have consistently established that miR (microRNA)-210 induction is a feature of the hypoxic response in both normal and transformed cells.
Simona Greco +2 more
exaly +2 more sources
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A review on the role of miR-210 in human disorders
Pathology Research and Practice, 2023Soudeh Ghafouri-Fard
exaly
miR-210 hypoxamiR in Angiogenesis and Diabetes
Antioxidants and Redox Signaling, 2022Germana Zaccagnini +2 more
exaly
Hypoxia-Induced miR-210 Is Necessary for Vascular Regeneration upon Acute Limb Ischemia
International Journal of Molecular Sciences, 2020Germana Zaccagnini +2 more
exaly

