Results 281 to 290 of about 482,752 (300)

miR-210 hypoxamiR in Angiogenesis and Diabetes

Antioxidants & Redox Signaling, 2021
Significance: microRNA-210 (miR-210) is the master hypoxia-inducible miRNA (hypoxamiR) since it has been found to be significantly upregulated under hypoxia in a wide range of cell types.
G. Zaccagnini, S. Greco, C. Voellenkle, C. Gaetano, F. Martelli   +4 more
semanticscholar   +3 more sources

The function of miR-210 in cardiovascular diseases

Biomedical Engineering Communications
Hong-Jin Chen, Ai-Fang Wang, Ying-Nan Song, Dong-Liang Yang, Xiong Chen   +4 more
semanticscholar   +2 more sources

Transglutaminase-Polyethyleneimine Nanoflowers Mediated Cellular Delivery of Anti-miR-210 for Effective Glioblastoma Therapy.

ACS Biomaterials Science & Engineering, 2023
Glioblastoma (GBM) is a deadly tumor of the central nervous system (CNS) having a dismal prognosis. miRNA-based therapeutics hold immense potential for GBM therapy; however, its delivery remains a daunting challenge.
Indranil Mondal, Syeda Warisul Fatima, S. Priya, S. Sengupta, S. Khare, Ritu Kulshreshtha   +5 more
semanticscholar   +1 more source

miR-210: a therapeutic target in cancer

Expert Opinion on Therapeutic Targets, 2012
As the predominant miRNA regulated by hypoxia, miR-210 correlates with survival in cancer patients. miR-210 may play important roles in regulation of cell growth, angiogenesis and apoptosis in different human tumor models, indicating that it can be used as a therapeutic target.This review covers all literature related to miR-210 in malignant tumors ...
Liu, Hong, Yu, Han, Hongwei, Zhang, Qingchuan, Zhao, Yuan, Qiao   +4 more
openaire   +2 more sources

The Angiogenesis Effects Of Electro-acupuncture Treatment Via Exosomal miR-210 In Cerebral Ischemia-Reperfusion Rats.

Current Neurovascular Research, 2022
BACKGROUND Acupuncture has been recommended as an alternative and complementary therapy for preventing and treating cerebral ischemia by the World Health Organization (WHO) for years. However, the mechanisms remain unclear.
Shuang Xu, Chun-Li Zeng, Sidorenko Ni, Yong-Jun Peng   +3 more
semanticscholar   +1 more source

miR-210-3p promotes obesity-induced adipose tissue inflammation and insulin resistance by targeting SOCS1 mediated NF-κB pathway.

Diabetes, 2022
Under the condition of chronic obesity, an increased level of free fatty acids along with low oxygen tension in the adipose tissue creates a pathophysiological adipose tissue microenvironment (ATenv) leading to the impairment of adipocyte function and ...
Debarun Patra, Soumyajit Roy, Leena Arora, Shaheen Wasil Kabeer, Satpal Singh, Upalabdha Dey, Dipanjan Banerjee, Archana Sinha, Suman Dasgupta, K. Tikoo, Aditya Kumar, Durba Pal   +11 more
semanticscholar   +1 more source

MKP‐1 is a target of miR‐210 and mediate the negative regulation of miR‐210 inhibitor on hypoxic hPASMC proliferation

Cell Biology International, 2014
AbstractChonic hypoxia, smooth muscle cell (SMC) proliferation and vascular remodeling are hallmark features of pathogenic pulmonary artery hypertension. MicroRNAs (miRNAs), endogenously expressed small noncoding RNAs, regulate gene expression at the post‐transcriptional level.
Youpeng, Jin, Tingting, Pang, Leif D, Nelin, Wei, Wang, Yulin, Wang, Jinchun, Yan, Chun, Zhao   +6 more
openaire   +2 more sources

MiR-210: A potential therapeutic target against radiation-induced enteropathy

Radiotherapy and Oncology, 2014
A previously undescribed and robust miR210 overexpression is shown in intestinal samples obtained from patients with radiation enteropathy and fibrotic cultured cells. In addition, miR-210 overexpression is repressed by antifibrotic treatment combining pentoxifylline and α-tocopherol.
Saad Hamama, Muhammad Zaeem Noman, Pascal Gervaz, Sylvie Delanian, Marie-Catherine Vozenin   +4 more
openaire   +2 more sources

A review on the role of miR-210 in human disorders

Pathology - Research and Practice, 2023
MicroRNA-210 (miR-210) is a miRNA with imperative effects in the pathophysiology of human disorders. miR-210 is encoded by MIR210 gene on chromosome 11p15.5. The stem-loop of this miRNA resides in an intron of the AK123483 noncoding RNA. This miRNA is a major hypoxamir whose expression is increased in hypoxic condition in several types of cells.
Sheyda Khalilian, Atefeh Bijanvand, Hamid Abedinlou, Soudeh Ghafouri-Fard   +3 more
openaire   +2 more sources

Exosomal miR-4639 and miR-210 in Plasma and Urine as Biomarkers in IgA Nephropathy

Nephron, 2022
Background: It has been widely recognized that exosomal miRNAs can participate in the pathogenesis of different renal disorders and serve as disease biomarkers.
Shuchen Zhao, Yangyang Sun, Qingyan Mao, Cuixing Zhou, Yimeng Chen, D. Xue   +5 more
semanticscholar   +1 more source