MiR-370-3p regulate TLR4/SLC7A11/GPX4 to alleviate the progression of glucocorticoids-induced osteonecrosis of the femoral head by promoting osteogenesis and suppressing ferroptosis [PDF]
Journal of Orthopaedic TranslationObjectives: Osteonecrosis of the femoral head (ONFH) represents a severe complication of glucocorticoids (GCs) therapy in clinical settings. MicroRNAs (miRNAs) are critically involved in the progression of GCs-induced ONFH, with ferroptosis playing a ...
Rongtai Zuo +7 more
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circRNA_101277 Influences Cisplatin Resistance of Colorectal Cancer Cells by Modulating the miR-370/IL-6 Axis [PDF]
Genetics Research, 2022 Background. Colorectal cancer (CRC) is among the most prevalent malignancies globally. Early detection of precancerous lesions through routine colonoscopy has led to a dramatic reduction in CRC-related incidence and mortality among those between the ages
Qing Lv +3 more
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Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells [PDF]
Scientific Reports, 2023 Endothelial dysfunction and inflammatory immune response trigger dedifferentiation of vascular smooth muscle cells (SMCs) from contractile to synthetic phenotype and initiate arterial occlusion.
Yerin Kim +10 more
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CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis. [PDF]
Aging (Albany NY), 2021 Metastasis is the leading cause of breast cancer (BC)-related deaths. Circular RNAs (circRNAs) have emerged as essential regulators for cancer progression and metastasis. Therefore, the objective of this study was to investigate the role of circRNAs in BC metastasis and related mechanism.
Zhang W +5 more
europepmc +4 more sources
miR‐370 is stage‐specifically expressed during mouse embryonic development and regulates Dnmt3a [PDF]
FEBS Letters, 2013 MicroRNAs (miRNAs) are small non‐coding RNAs that participate in a large variety of biological processes. In this paper, the spatiotemporal expression pattern of miR‐370 was characterized during mouse embryonic development, and was found to be stage‐ and tissue‐specifically expressed.
Qi, Liu +7 more
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CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis [PDF]
Cardiovascular Therapeutics, 2022 Background. Circular RNA Transformation/Transcription Domain Associated Protein (circTRRAP, hsa_circ_0081241) was abnormally upregulated in acute myocardial infarction (AMI) patients. However, its biological role and functional mechanism in AMI remain to
Yuan Zhang +5 more
doaj +2 more sources
miR-370 mimic inhibits replication of Japanese encephalitis virus in glioblastoma cells
Neuropsychiatric Disease and Treatment, 2016 Wenjuan Li,1 Peng Cheng,2 Shangdan Nie,1 Wen Cui1 1School of Forensic and Laboratory Medicine, Jining Medical University, 2Shandong Academy of Medical Sciences, Shandong Institute of Parasitic Diseases, Jining, People’s Republic of ...
Li W, Cheng P, Nie S, Cui W
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Chi-miR-370-3p regulates hair follicle morphogenesis of Inner Mongolian cashmere goats. [PDF]
G3 (Bethesda), 2021 Abstract MicroRNAs (miRNAs), a class of 22 nucleotide (nt) noncoding RNAs, negatively regulate mRNA posttranscriptional modification in various biological processes. Morphogenesis of skin hair follicles in cashmere goats is a dynamic process involving many key signaling molecules, but the associated cellular biological mechanisms induced
Hai E +16 more
europepmc +5 more sources
CircRNA_1809 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells through miR-370-3p [PDF]
Scientific ReportsCircular RNA (circRNA) is a unique closed ring structure of noncoding RNA. Although many human diseases have been confirmed to be inextricably linked with circRNAs, whether circRNAs have a potential regulatory function in the osteogenic differentiation ...
Lei Zhang +6 more
doaj +2 more sources
Increased circulating miR-370-3p regulates steroidogenic factor 1 in endometriosis [PDF]
American Journal of Physiology - Endocrinology and Metabolism, 2019 Endometriosis is a gynecologic disease common among reproductive-aged women caused by the growth of endometrial tissue outside the uterus. Altered expression of numerous genes and microRNAs has been reported in endometriosis. Steroidogenic factor 1 (SF-1), an essential transcriptional regulator of multiple genes involved in estrogen biosynthesis, is ...
Ramanaiah Mamillapalli, Hugh S Taylor
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