Results 31 to 40 of about 10,058 (237)
BMC Pulmonary Medicine, 2021 Purpose Long non-coding RNAs (lncRNAs) play important roles in the development of pneumonia. We aimed to explore the role of the lncRNA KCNQ1OT1 in pneumonia and its underlying mechanisms.
Ping Wang +3 more
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The role of miR-370 in fibrosis after myocardial infarction
Molecular Medicine Reports, 2017 In the present study, we investigated the expression of miR‑370 in the border area of infarction after myocardial infarction and its role in the process of post‑infarction fibrosis. A myocardial infarction model in Sprague-Dawley rats was established. After two weeks, the mRNA levels of transforming growth factor‑β1 (TGFβ1), TGFβRII, ColIa1, ColIIIa1 ...
Yuan, Hui, Gao, Jie
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Journal of Pharmacological Sciences, 2018 It has been reported that PAQR4 (Progestin and AdipoQ Receptor 4) expression is closely associated with progression of many cancers and microRNA (miRNA) processing.
Ye Feng +5 more
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Increased circulating miR-370-3p regulates steroidogenic factor 1 in endometriosis [PDF]
American Journal of Physiology-Endocrinology and Metabolism, 2019 Endometriosis is a gynecologic disease common among reproductive-aged women caused by the growth of endometrial tissue outside the uterus. Altered expression of numerous genes and microRNAs has been reported in endometriosis. Steroidogenic factor 1 (SF-1), an essential transcriptional regulator of multiple genes involved in estrogen biosynthesis, is ...
Zhuoying, Hu +2 more
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The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia
Molecular Cancer, 2012 Background Recent evidence has accumulated that MicroRNA (miRNA) dysregulation occurs in the majority of human malignancies including acute myeloid leukemia (AML) and may contribute to onco-/leukemo-genesis.
Zhang Xiaolu +8 more
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MiR‑370 promotes apoptosis in colon cancer by directly targeting MDM4
Oncology Letters, 2017 MicroRNA (miR)-370 functions as a tumor suppressor or promoter in several cancers. However, the expression and biological role of miR-370 in colon cancer remains undefined. In the present study, miR-370 expression in both normal and malignant colon tissues was quantified by quantitative polymerase chain reaction.
Shen, Xiaogang +5 more
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miR‐370 is stage‐specifically expressed during mouse embryonic development and regulates Dnmt3a [PDF]
FEBS Letters, 2013 MicroRNAs (miRNAs) are small non‐coding RNAs that participate in a large variety of biological processes. In this paper, the spatiotemporal expression pattern of miR‐370 was characterized during mouse embryonic development, and was found to be stage‐ and tissue‐specifically expressed.
Qi, Liu +7 more
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Wnt7a and miR-370-3p: new contributors to bladder cancer invasion
Biotarget, 2018 In eukaryotes, microRNAs (miRNAs) are central regulators of gene expression. These small noncoding RNAs are about 19–24 nucleotides long (1). miRNAs can silence gene expression by binding to a complementary sequence in the 3'-UTR of the target gene, which then triggers mRNA degradation.
Danielle, Scheunemann +5 more
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Expression of microRNA-370 in human breast cancer compare with normal samples
Advanced Biomedical Research, 2016 Background: Breast cancer is the second leading cause of deaths from cancer in the woman. MicroRNAs (miRNAs) are endogenous noncoding RNAs that are known critical player in carcinogenesis. The role of miR-370 in malignancies remains controversial because
Halimeh Mollainezhad +4 more
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MiR-370-5p inhibits the progression of breast cancer via targeting LUC7L3
Journal of receptor and signal transduction research, 2020 Breast cancer is one of the most common malignancies and one of the leading causes of cancer-induced mortality among women. Over the past decades, the occurrence of breast cancer has been a significant increase. As documented in numerous researches, microRNAs (miRNAs) play vital roles in a wide range of biological processes associated with the ...
Kai, Sang +5 more
openaire +2 more sources