Results 31 to 40 of about 11,305 (171)

Circular RNA CircITGA7 Promotes Tumorigenesis of Osteosarcoma via miR-370/PIM1 Axis. [PDF]

open access: yesComput Math Methods Med, 2020
Many studies have shown that there are many circular RNA (circRNA) expression abnormalities in osteosarcoma (OS), and this abnormality is related to the development of osteosarcoma. But at present, it is unclear as to what circITGA7 has in the OS and what it does.
Fang C, Wang X, Guo D, Fang R, Zhu T.
europepmc   +4 more sources

Inhibition of intervertebral disc disease progression via the circPKNOX1-miR-370-3p-KIAA0355 axis. [PDF]

open access: yesCell Death Discov, 2021
AbstractThe molecular mechanism underlying the development of intervertebral disc disease (IVDD) is not completely understood. Circular RNAs (circRNAs) play a significant role in the occurrence and development of various diseases, and studies have shown that circPKNOX1 is involved in the compensatory response of extracellular matrix synthesis and ...
Huang Y   +8 more
europepmc   +5 more sources

CircAGFG1 promotes cervical cancer progression via miR-370-3p/RAF1 signaling [PDF]

open access: yesBMC Cancer, 2019
Background In past decades, circular RNAs (circRNAs) have achieved increasing attention because of its regulatory role in different kinds of cancers. However, how circAGFG1 regulates cervical cancer (CC) is still largely undiscovered.
Fengqin Wu, Jingjing Zhou
doaj   +3 more sources

lncRNA NEAT1 mediates sepsis progression by regulating Irak2 via sponging miR-370-3p [PDF]

open access: yesBiology Open, 2020
Sepsis is a life-threatening condition and often associated with multiple organ failure. Nuclear-enriched abundant transcript 1 (NEAT1), a member of the long non-coding RNAs (lncRNAs), was reported to be involved in the regulation of sepsis progression ...
Ting Xiao   +3 more
doaj   +3 more sources

Hsa_circ_0009096/miR-370-3p modulates hepatic stellate cell proliferation and fibrosis during biliary atresia pathogenesis [PDF]

open access: yesPeerJ
Background Hepatic stellate cell (HSC) activation and hepatic fibrosis mediated biliary atresia (BA) development, but the underlying molecular mechanisms are poorly understood.
Zhouguang Wu   +7 more
doaj   +3 more sources

MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation [PDF]

open access: yesBiochemical Pharmacology, 2017
Cytochrome P450 2D6 (CYP2D6) participates in the metabolism of approximately 20-25% of prescribed drugs. Genetic polymorphisms influence the expression and/or activity of CYP2D6, and inter-individual differences in drug activation and elimination caused by CYP2D6 genetic variants were reported. However, little is known about the potential modulation of
Lin-juan Zeng, Yinting Chen, Li-Rong Yu
exaly   +3 more sources

Circ_0010729 knockdown protects cardiomyocytes against hypoxic dysfunction via miR-370-3p/TRAF6 axis. [PDF]

open access: yesEXCLI J, 2020
Few studies have addressed the mechanism by which circ_0010729 regulates hypoxia-induced cell injury in cardiovascular diseases. However, its role and its regulatory mechanism in myocardial infarction remain to be explored.
Zhang J, Gao C, Zhang J, Ye F.
europepmc   +3 more sources

miR-370 targeted FoxM1 functions as a tumor suppressor in laryngeal squamous cell carcinoma (LSCC)

open access: yesBiomedicine and Pharmacotherapy, 2014
microRNAs, a family of small non-coding RNAs, involve in the pathogenesis of several types of cancers, including laryngeal squamous cell carcinoma (LSCC). MiR-370 is frequently aberrant expressed in various types of human cancer including LSCC. However, the role for miR-370 in LSCC remains elusive.
Xinliang Pan
exaly   +3 more sources

The miR-370/UQCRC2 axis facilitates tumorigenesis by regulating epithelial-mesenchymal transition in Gastric Cancer. [PDF]

open access: yesJ Cancer, 2020
Ubiquinol-cytochrome c reductase core protein 2 (UQCRC2) is an important mitochondrial complex III subunit. This study investigated the role of UQCRC2 in gastric cancer (GC) and its upstream regulatory microRNAs (miRNAs). UQCRC2 expression levels were lower in GC tissues than non-carcinoma tissues.
Wang DW   +7 more
europepmc   +4 more sources

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