Results 51 to 60 of about 336,133 (179)

microRNA-370-5p inhibits non-small cell lung cancer cell proliferation and migration and promotes apoptosis by targeting KPNA3

open access: yesBangladesh Journal of Pharmacology
This study aimed to investigate the biological function of microRNA-370-5p (miR-370-5p) in non-small cell lung cancer (NSCLC) and its regulatory relationship with KPNA3.
Zhouli Ding, Yali Yang, Jingjing Wang
doaj   +1 more source

MiR-370 enhances cell cycle and represses lipid accumulation in porcine adipocytes

open access: yesAnimal Biotechnology, 2019
MicroRNAs (miRNAs) are emerging as an important regulator during adipose development. Previous studies have revealed that miR-370 is related to lipid metabolic homeostasis, however, its roles in lipid accumulation remain to be established. In this study, we demonstrated that ssc-miR-370 was highly conserved across domestic animals, and relatively ...
Yixin Chu, Ying Yao, Xiao Li
openaire   +2 more sources

MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation [PDF]

open access: yesBiochemical Pharmacology, 2017
Cytochrome P450 2D6 (CYP2D6) participates in the metabolism of approximately 20-25% of prescribed drugs. Genetic polymorphisms influence the expression and/or activity of CYP2D6, and inter-individual differences in drug activation and elimination caused by CYP2D6 genetic variants were reported. However, little is known about the potential modulation of
Linjuan, Zeng   +15 more
openaire   +2 more sources

MiR-370 and miR-543 regulate endogenous DNAJB1.

open access: yes, 2018
(A) A pool of miR-370 and miR-543 mimics was transfected into Hela cells and DNAJB1 protein was detected on a western blot using DNAJB1 specific antibodies. GAPDH was detected as loading control. A representative blot of an n = 4 is shown. p = 0.0439 (B)
Bernd O. Evert (5608034)   +9 more
core   +1 more source

A Novel Circulating MiRNA-Based Signature for the Diagnosis and Prognosis Prediction of Early-Stage Cervical Cancer

open access: yesTechnology in Cancer Research & Treatment, 2020
Background: MicroRNAs (miRNAs) have been shown to play a key role in regulating the progression of cervical cancer (CC). This study aimed to develop a circulating miRNA-based molecular signature for the diagnosis and prognosis prediction of early-stage ...
Huajuan Qiu MD   +5 more
doaj   +1 more source

MOESM1 of CircAGFG1 promotes cervical cancer progression via miR-370-3p/RAF1 signaling

open access: yes, 2019
Additional file 1. Figure S1. (A) The heatmap plotted through the results from qRT-PCR told us that miR-370-3p was the most up-regulated miRNA in response to circAGFG1 down-regulation in CC cells.
Jingjing Zhou (179820)   +1 more
core   +1 more source

hsa_circ_0003596, as a novel oncogene, regulates the malignant behavior of renal cell carcinoma by modulating glycolysis

open access: yesEuropean Journal of Medical Research, 2023
Background This research was planned to analyze hsa_circ_0003596 (circCOL5A1) and glycolysis-focused mechanisms in renal cell carcinoma (RCC). Methods circCOL5A1, miR-370-5p, and PRKCSH levels were determined in RCC tissues and selected cell lines by RT ...
QingZhi Xie   +8 more
doaj   +1 more source

miR-370 induces growth retardation.

open access: yes, 2012
A.. HuCCT1 malignant cholangiocytes display decreased growth upon reinforcement of miR-370 expression. X-axis – HuCCT1 cells counted at day 1, 3, 5 and 7 after transfection with miR-370M, or NSM, respectively.
Fangmei An (126976)   +11 more
core   +1 more source

Image_1_Circular RNA hsa-circ-0005238 enhances trophoblast migration, invasion and suppresses apoptosis via the miR-370-3p/CDC25B axis.TIF

open access: yes, 2022
BackgroundFetal growth restriction (FGR) is attributed to various maternal, fetal, and placental factors. Trophoblasts participate in the establishment and maintenance of pregnancy from implantation and placentation to providing nutrition to fetus ...
Litong Zhu (6578963)   +4 more
core   +1 more source

The protective effect of bone marrow-derived mesenchymal stem cells in liver ischemia/reperfusion injury via down-regulation of miR-370 [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2019
Objective(s): Liver transplantation is the most important therapy for end-stage liver disease and ischemia reperfusion (I/R) injury is indeed a risk factor for hepatic failure after grafting. The role of miRNAs in I/R is not completely understood.
Mohamad Ali Zare   +3 more
doaj   +1 more source

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