Results 51 to 60 of about 262,961 (265)
The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia
Molecular Cancer, 2012 Background Recent evidence has accumulated that MicroRNA (miRNA) dysregulation occurs in the majority of human malignancies including acute myeloid leukemia (AML) and may contribute to onco-/leukemo-genesis.
Zhang Xiaolu +8 more
doaj +1 more source
MiR‑370 promotes apoptosis in colon cancer by directly targeting MDM4
Oncology Letters, 2017 MicroRNA (miR)-370 functions as a tumor suppressor or promoter in several cancers. However, the expression and biological role of miR-370 in colon cancer remains undefined. In the present study, miR-370 expression in both normal and malignant colon tissues was quantified by quantitative polymerase chain reaction.
Shen, Xiaogang +5 more
openaire +3 more sources
Wnt7a and miR-370-3p: new contributors to bladder cancer invasion
Biotarget, 2018 In eukaryotes, microRNAs (miRNAs) are central regulators of gene expression. These small noncoding RNAs are about 19–24 nucleotides long (1). miRNAs can silence gene expression by binding to a complementary sequence in the 3'-UTR of the target gene, which then triggers mRNA degradation.
Danielle, Scheunemann +5 more
openaire +2 more sources
Expression of microRNA-370 in human breast cancer compare with normal samples
Advanced Biomedical Research, 2016 Background: Breast cancer is the second leading cause of deaths from cancer in the woman. MicroRNAs (miRNAs) are endogenous noncoding RNAs that are known critical player in carcinogenesis. The role of miR-370 in malignancies remains controversial because
Halimeh Mollainezhad +4 more
doaj +1 more source
MiR-370-5p inhibits the progression of breast cancer via targeting LUC7L3
Journal of receptor and signal transduction research, 2020 Breast cancer is one of the most common malignancies and one of the leading causes of cancer-induced mortality among women. Over the past decades, the occurrence of breast cancer has been a significant increase. As documented in numerous researches, microRNAs (miRNAs) play vital roles in a wide range of biological processes associated with the ...
Kai, Sang +5 more
openaire +2 more sources
Molecular Therapy: Nucleic Acids, 2018 In the last decade, microRNAs (miRs) have been described as biomarkers and therapeutic agents. Based on this finding, our aim here is to know if (1) miRNA-370-3p can be used as a biomarker associated with a favorable survival and if (2) miRNA-370-3p can ...
Arulraj Nadaradjane +6 more
doaj +1 more source
Immunity, Inflammation and Disease, 2023 Background Circular RNAs have emerged as important regulators in the pathogenesis of human diseases, including infantile pneumonia (IP). In this study, we aimed to explore the effects of circ_0035292 on lipopolysaccharide (LPS)‐treated Wistsar Institute (
Ying Guo, Zhouzhen Li, Chen Cheng
doaj +1 more source
Regulation of SLD5 gene expression by miR-370 during acute growth of cancer cells [PDF]
Scientific Reports, 2016 AbstractSLD5 is a member of the GINS complex, essential for DNA replication in eukaryotes. It has been reported that SLD5 is involved in early embryogenesis in the mouse and cell cycle progression and genome integrity in Drosophila. SLD5 may be involved in malignant tumor progression, but its relevance in human cancer has not been determined.
Keitaro Yamane +7 more
openaire +2 more sources
RETRACTED ARTICLE: MiR-370-5p inhibits the progression of breast cancer via targeting LUC7L3
, 2020 We, the Editors and Publisher of the Journal of Receptors and Signal Transduction, have retracted the following article: Kai Sang, Tongbo Yi, Xinxin Huang, Chi Pan, Jian Zhou & Lei Yu (2021) MiR-370-5p inhibits the progression of breast cancer via ...
Lei Yu (70258) +5 more
core +1 more source
Cancer Cell International, 2020 Background Mounting evidence implicates circular RNAs (circRNAs) in various biological processes during cancer progression. Gastric cancer is a main cause of cancer-related deaths worldwide.
Nan Zhou +5 more
doaj +1 more source