Results 71 to 80 of about 336,133 (179)

MOESM4 of CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling

, 2019
Additional file 4: Figure S3. MiR-370-3p showed a strong effect on the migration, invasion, and EMT process than miR-877-3p in MG63 and U2OS cells. (a) MiR-370-3p and miR-877-3p inhibited MG63 and U2OS cells to migrate and invade through transwells ...
Shengyu Wang (306423), Jianjun Ma (158111), Yute Yang (5463545), Gang Liu (81776), Yizheng Wu (1665766), Panyang Shen (7587599), Junxin Chen (2951379), Xiangqian Fang (6050843), Shuai Chen (506142), Shuying Shen (6050849), Shunwu Fan (4411273), Hongfei Wu (470334), Yifan Fang (7587602), Ziang Xie (3743974)   +13 more
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Functional analysis showing that miR-370 regulates NF1.

, 2012
(A) miRNAs expression analysis by real-time PCR after transfection with pre-miRs-370, −379, −432 and −494. (B) Western blot showing NF1 after transfection with pre-miR-370.
Remedios Castello-Cros (127012), María J. Calasanz (127008), María D. Odero (127018), Cristina Cirauqui (126994), Nerea Marcotegui (127003), Laura García-Ortí (126989), Ion Cristóbal (126992), Elisabet Guruceaga (126998)   +7 more
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MOESM7 of CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling

, 2019
Additional file 7: Figure S6. MiR-370-3p inhibits Wnt/β-catenin signaling. (a-c) Transfection with miR-370-3p mimics significantly downregulated the expression of β-catenin, C-myc and cyclinD1 as revealed by (a) qRT-PCR, (b) western blot analysis and (c)
Shengyu Wang (306423), Jianjun Ma (158111), Yute Yang (5463545), Gang Liu (81776), Yizheng Wu (1665766), Panyang Shen (7587599), Junxin Chen (2951379), Xiangqian Fang (6050843), Shuai Chen (506142), Shuying Shen (6050849), Shunwu Fan (4411273), Hongfei Wu (470334), Yifan Fang (7587602), Ziang Xie (3743974)   +13 more
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Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease

Lipids in Health and Disease, 2012
Background Hyperlipidemia plays a crucial role in the development and progression of coronary artery disease (CAD). Recent studies have identified that microRNAs (miRNAs) are important regulators of lipid metabolism, but little is known about the ...
Gao Wei, He Hui-Wei, Wang Ze-Mu, Zhao Huan, Lian Xiao-Qing, Wang Yong-Sheng, Zhu Jun, Yan Jian-Jun, Zhang Ding-Guo, Yang Zhi-Jian, Wang Lian-Sheng   +10 more
doaj   +1 more source

Inhibition of miR-370 activates the FOXO1 pathway. A,

, 2012
Relative luciferase activity assay of PC3 and DU145 cells co-transfected with the pGL3-FOXO1-3′UTR plasmid and increasing amounts (20, 50 nM) of miR-370 mimic- or miR-370 inhibitor-oligonucleotides, 48 hours after transfection, respectively.
Jincan He (136360), Huabin Sun (136356), Ziqing Wu (136354), Weixia Zeng (136358), Xiangming Mao (136362)   +4 more
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MOESM1 of Circular RNA circ_0003204 inhibits proliferation, migration and tube formation of endothelial cell in atherosclerosis via miR-370-3p/TGFβR2/phosph-SMAD3 axis

, 2020
Additional file 1: Figure S1. GO and pathway analysis of the upregulated genes in GSE13139. Dot plot representing biological process with the top 10 most significantly enriched terms (A), cellular component (B), molecular function (C), KEGG pathways (D ...
Jing Yuan (217967), Aihua Wang (2481142), Shanchao Zhang (500712), Zhihua Si (7341389), Shan Qiao (646492), Shan Xu (454389), Xuxu Xu (8222697), Guixiang Song (65112), Yang Yang (45629)   +8 more
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MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism[S]

Journal of Lipid Research, 2010
We previously observed that treatment of mice with a dominant negative form of cJun (dn-cJun) increased the expression of genes involved in lipid metabolism and modulated the expression of nine microRNAs (miR).
Dimitrios Iliopoulos, Konstantinos Drosatos, Yaeko Hiyama, Ira J. Goldberg, Vassilis I. Zannis   +4 more
doaj   +1 more source

Methylation of IG-DMR-CG6 influences miR-370 expression.

, 2012
A... IG-DMR-CG6 is hypermethylated in human CCAs vs. matched normal tissues. Each line indicates a single clone, and each circle denotes the cytosine of a CpG site; filled and open circles represent methylated and unmethylated cytosines, respectively. B..
Fangmei An (126976), Masaharu Ishida (126995), Qing Xie (104232), Timothy M. Pawlik (126991), Anne C. Ferguson-Smith (127005), Yuriko Mori (43703), Sarah Allen (126984), Florin M. Selaru (127013), Sumitaka Yamanaka (126980), Gregory J. Gores (126988), Lewis R. Roberts (119660), Esteban Mezey (127000)   +11 more
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Long noncoding RNA LINC00707 sponges miR-370-3p to promote osteogenesis of human bone marrow-derived mesenchymal stem cells through upregulating WNT2B

Stem Cell Research & Therapy, 2019
Background Human bone marrow-derived mesenchymal stem cells (HBMSCs) are characterized by multiple differentiation potential and potent self-renewal ability, yet much remains to be elucidated on what determines these properties. Long-chain noncoding RNAs
Bo Jia, Zhiping Wang, Xiang Sun, Jun Chen, Jianjiang Zhao, Xiaoling Qiu   +5 more
doaj   +1 more source

MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome. [PDF]

, 2014
Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias.
Corfield, VA, Christiansen, M, Corfield, Valerie A, Christiansen, Kasper M, Carlsen, AL, Christiansen, KM, Carlsen, Anting L, Behr, Elijah R, Kanters, JK, Hedley, Paula L, Kanters, Jørgen K., Christiansen, Michael, Behr, ER, Hedley, PL   +13 more
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