Results 81 to 90 of about 11,305 (171)

Roles of microRNA on cancer cell metabolism [PDF]

, 2012
Advanced studies of microRNAs (miRNAs) have revealed their manifold biological functions, including control of cell proliferation, cell cycle and cell death.
Bing Chen, Hongbin Li, Pengbo Yang, Shufang Liang, Xia Zhao, Xiao Zeng, Xinyu Liu   +6 more
core   +1 more source

Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease

Lipids in Health and Disease, 2012
Background Hyperlipidemia plays a crucial role in the development and progression of coronary artery disease (CAD). Recent studies have identified that microRNAs (miRNAs) are important regulators of lipid metabolism, but little is known about the ...
Gao Wei, He Hui-Wei, Wang Ze-Mu, Zhao Huan, Lian Xiao-Qing, Wang Yong-Sheng, Zhu Jun, Yan Jian-Jun, Zhang Ding-Guo, Yang Zhi-Jian, Wang Lian-Sheng   +10 more
doaj   +1 more source

SNHG15 is involved in the progression of atherosclerosis through targeted regulation of miR-370-3p and bioinformatics analysis

Archives of Medical Science
Introduction This study aimed to explore the expression of SNHG15 in atherosclerotic population and further evaluate the regulatory mechanism of SNHG15 in AS. Material and methods qRT-PCR was used to detect the level of SNHG15 in serum samples.
Wan Pan, Yan Zhou, Fan Zhang, Yingying Zhang, Wei Li, Chengpeng Li, Liqun He   +6 more
doaj   +1 more source

MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism[S]

Journal of Lipid Research, 2010
We previously observed that treatment of mice with a dominant negative form of cJun (dn-cJun) increased the expression of genes involved in lipid metabolism and modulated the expression of nine microRNAs (miR).
Dimitrios Iliopoulos, Konstantinos Drosatos, Yaeko Hiyama, Ira J. Goldberg, Vassilis I. Zannis   +4 more
doaj   +1 more source

Effect of BRAF mutation on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model [PDF]

, 2007
BACKGROUND: microRNAs (miRNAs) are a group of non-coding single stranded RNAs measuring approximately 22 nucleotides in length that have been found to control cell growth, differentiation and apoptosis.
Cahill, S, Denning, K, Flavin, R, Guenther, SM, Henfrey, R, Li, J, O'Leary, JJ, Potratz, A, Sheils, O, Smyth, P   +9 more
core   +3 more sources

Long noncoding RNA LINC00707 sponges miR-370-3p to promote osteogenesis of human bone marrow-derived mesenchymal stem cells through upregulating WNT2B

Stem Cell Research & Therapy, 2019
Background Human bone marrow-derived mesenchymal stem cells (HBMSCs) are characterized by multiple differentiation potential and potent self-renewal ability, yet much remains to be elucidated on what determines these properties. Long-chain noncoding RNAs
Bo Jia, Zhiping Wang, Xiang Sun, Jun Chen, Jianjiang Zhao, Xiaoling Qiu   +5 more
doaj   +1 more source

Circulating microRNAs and life expectancy among identical twins [PDF]

, 2016
Human life expectancy is influenced not only by longevity assurance mechanisms and disease susceptibility loci but also by the environment, gene–environment interactions, and chance.
Baxter, David, Dai, Jun, Kim, Taek-Kyun, Krasnow, Ruth E., Reed, Terry, Scherler, Kelsey, Wang, Kai, Wu, Shenghui, Wu, Xiaogang   +8 more
core   +1 more source

Gene Expression of MicroRNA-370 in Some Iraqi Women with Breast Cancer

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2021
Breast cancer becomes a major threat to female health, many reports refer to a high incidence of breast cancer in Iraq; especially, in the last years. The micro RNA-370 molecules have not been reported in Iraqi cancer patients.
Wafaa Sabri Mahood, Maryam Jasim Hasan, Mohammed Jasim Mohammed   +2 more
doaj   +1 more source

The long non-coding RNA Kcnq1ot1 controls maternal p57 expression in muscle cells by promoting H3K27me3 accumulation to an intragenic MyoD-binding region [PDF]

, 2019
BACKGROUND: The cell-cycle inhibitor p57kip2 plays a critical role in mammalian development by coordinating cell proliferation and differentiation in many cell types.
Andresini, Oriella, Maione, Rossella, Matteini, Francesca, Petrai, Stefano, Rossi, Marianna Nicoletta, Santini, Tiziana   +5 more
core   +4 more sources

miR-370 regulates ISG15 expression and influences IFN-α sensitivity in hepatocellular carcinoma cells

Cancer Biomarkers, 2018
BACKGROUND: Interferon-α (IFN-α) is an adjuvant to chemotherapy and radiotherapy for hepatocellular carcinoma (HCC), but some HCC patients do not respond to treatment with IFN-α. METHODS: We performed loss-of-function and gain-of-function experiments to examine the role of ISG15 in the IFN-α sensitivity of LH86, HLCZ01, SMMC7721, and Huh7 cell lines ...
Zhuo, Liu, Min, Ma, Lei, Yan, Shilin, Chen, Sha, Li, Darong, Yang, Xiaohong, Wang, Hua, Xiao, Hongyu, Deng, Haizhen, Zhu, Chaohui, Zuo, Man, Xia   +11 more
openaire   +3 more sources