Results 101 to 110 of about 11,305 (171)

The microRNA-29 family in cartilage homeostasis and osteoarthritis [PDF]

, 2015
MicroRNAs have been shown to function in cartilage development and homeostasis, as well as in progression of osteoarthritis. The objective of the current study was to identify microRNAs involved in the onset or early progression of osteoarthritis and ...
A Kozomara, A Martinez-Sanchez, A Sorrentino, AJ Kriegel, AL Olex, Anne M. Delany, B Ma, BN Davis, C Yan, D Guerit, David A. Young, DJ Blasioli, DJ Hunter, DP Bartel, E Kozhemyakina, E Wienholds, EA Riordan, FE Nicolas, H Akiyama, H Pais, H Wang, Ian M. Clark, JL Mott, K Kapinas, K Kapinas, KA Dudek, KA Staines, KL Culley, KW Chong, L Jin, L Tuddenham, Linh T. T. Le, LT Le, M Cucchiarini, M Ha, M Himly, M Tan, M Yang, Matthew J. Barter, MB Goldring, MB Goldring, MH Bosch van den, MJ Barter, N Crowe, Natalie Crowe, Q Zhang, R Liu-Bryan, RK Davidson, S Liu, S Miyaki, S Shi, S Thysen, Simon T. Donell, SL Chia, SS Glasson, Tamas Dalmay, TE Swingler, Tonia L. Vincent, Tracey E. Swingler, V Korinek, V Lefebvre, W Kim, W Qin, XL Yuan, Y He, Y Nakamura, Y Nakamura, Y Zhuo   +67 more
core   +1 more source

Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p

BMC Cancer, 2019
Background Glutamate metabotropic receptors (GRM) play a variety of roles in neuronal cells. However, their clinical significance and biological functions in breast cancer remain unknown. Methods RNA sequencing data of breast cancer was obtained from the
Bin Xiao, Daxiang Chen, Quan Zhou, Jianfeng Hang, Weiyun Zhang, Zhenzhan Kuang, Zhaohui Sun, Linhai Li   +7 more
doaj   +1 more source

Circular RNA circ_0003204 inhibits proliferation, migration and tube formation of endothelial cell in atherosclerosis via miR-370-3p/TGFβR2/phosph-SMAD3 axis

Journal of Biomedical Science, 2020
Background Circular RNAs (circRNAs) represent a class of non-coding RNAs (ncRNAs) which are widely expressed in mammals and tissue-specific, of which some could act as critical regulators in the atherogenesis of cerebrovascular disease.
Shanchao Zhang, Guixiang Song, Jing Yuan, Shan Qiao, Shan Xu, Zhihua Si, Yang Yang, Xuxu Xu, Aihua Wang   +8 more
doaj   +1 more source

lncRNA BCAR4 sponges miR‑370‑3p to promote bladder cancer progression via Wnt signaling

International Journal of Molecular Medicine, 2019
Accumulating evidence suggests that the aberrant expression of long non‑coding RNAs (lncRNAs) is involved in the initiation, development and metastasis of bladder cancer (BC). Although several differentially expressed lncRNAs have been identified via lncRNA expression profiling of BC tissues, their functions and the molecular mechanisms underlying ...
Zhang, Rongkui, Wang, Jiping, Jia, Er'na, Zhang, Jialiang, Liu, Nan, Chi, Changliang   +5 more
openaire   +3 more sources

miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition

Drug Design, Development and Therapy, 2020
Lianjie Lin,1 Dongxu Wang,1 Suxuan Qu,1 Hong Zhao,1,2 Yan Lin1 1Department of Gastroenterology and Hepatology, Shengjing Hospital of China Medical University, Shenyang 110004, People’s Republic of China; 2Department of Gastroenterology, The Second ...
Lin L, Wang D, Qu S, Zhao H, Lin Y
doaj  

Integração de dados georreferenciados no mapeamento dos biótopos do gafanhoto praga do Mato Grosso. [PDF]

, 2014
Divulga os resultados do projeto, realizado em parceria com o PRIFAS (França), sobre os gafanhotos do Estado do Mato Grosso, particularmente a espécie Rhammatocerus schistocercoides (Rehn, 1906) (Acrididae, Gomphocerinae).
BATISTELLA, M., LECOQ, M., MIRANDA, E. E. de, PIEROZZI JR. I.   +3 more
core  

miRNA regulation of cytotoxic effects in mouse Sertoli cells exposed to nonylphenol [PDF]

, 2011
Background: It is known that some environmental chemicals affect the human endocrine system. The harmful effects of endocrine disrupting chemical (EDC) nonylphenol (NP) have been studied since the 1980s.
Jin-Sung Choi, Jung-Hwa Oh, Han-Jin Park, Mi-Sun Choi, Se-Myo Park, Seung-Jun Kang, Moon-Ju Oh, Seung Jun Kim, Seung Yong Hwang, Seokjoo Yoon   +9 more
core   +1 more source

Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues [PDF]

, 2006
PURPOSE: Diffuse large B-cell lymphoma (DLBCL) heterogeneity has prompted investigations for new biomarkers that can accurately predict survival. A previously reported 6-gene model combined with the International Prognostic Index (IPI) could predict ...
Abajo, A. (Ana), Agirre-Ena, X. (Xabier), Bandres, E. (Eva), Cubedo, E. (Elena), Garcia-Foncillas, J. (Jesús), Malumbres, R. (Raquel), Monzo, M. (M.), Moreno, I. (I.), Navarro, A. (A.), Ramirez, N. (Natalia), Zarate, R. (Ruth)   +10 more
core  

Physcion induces apoptosis in hepatocellular carcinoma by modulating miR-370.

American journal of cancer research
Hepatocellular carcinoma (HCC) is one of the most common and aggressive malignancies. The current study is designed to explore the role of physcion, a major active ingredient in several traditional herbal medicinal plants, for the treatment of HCC. HCC cell lines, SMMC7721 and HepG2, were treated with physcion and its apoptosis-inducing effect was ...
Xiaoping, Pan, Haixia, Wang, Dongmeng, Tong, Chen, Wang, Li, Sun, Chunjuan, Zhao, Yan, Li, Lida, Zhu, Di, Wu   +8 more
openaire   +1 more source

MiR‑370 inhibits the oxidative stress and apoptosis of cardiac myocytes induced by hydrogen peroxide by targeting FOXO1

Experimental and Therapeutic Medicine, 2019
Myocardial infarction, one of the main factors that threatens human health, leads to cardiac cell death. Myocardial cells suffer ischemia and hypoxia for a long period of time, which can lead to irreversible cell death or apoptosis and cardiac dysfunction.
Qiu, Zhanjun, Wang, Lei, Mao, Huaiyu, Xu, Feng, Sun, Bin, Lian, Xinbao, Wang, Jiali, Kong, Feng, Wang, Lina, Chen, Yuguo   +9 more
openaire   +3 more sources