Results 91 to 100 of about 336,133 (179)

hsa_circ_0061140 Knockdown Reverses FOXM1-Mediated Cell Growth and Metastasis in Ovarian Cancer through miR-370 Sponge Activity

Molecular Therapy: Nucleic Acids, 2018
Circular RNAs (circRNAs) are a class of noncoding RNAs that regulate gene expression at the posttranscriptional level. The specific functions of circRNAs in ovarian cancer are yet to be established.
Qizhen Chen, Jiarong Zhang, Yinyan He, Yanqiu Wang   +3 more
doaj   +1 more source

Lipopolysaccharide-induced bacterial infection model: microRNA-370-3p participates in the anti-infection response by targeting the macrophage TLR4-NLRP3 caspase-1 cellular pyroptosis pathway

International Journal of Immunopathology and Pharmacology
Objective To explore the effect of miR-370-3p on LPS triggering, in particular its involvement in disease progression by targeting the TLR4-NLRP3-caspase-1 cellular pyroptosis pathway in macrophages.
Wen Liu, Haiyun Chen, Fengli Xia, Lu Lu, Abdusemer Reyimu, Paerhati Pawuziye, Yadong Li, Aimin Xu, Xiaoguang Zou   +8 more
doaj   +1 more source

miR-370 targeted FoxM1 functions as a tumor suppressor in laryngeal squamous cell carcinoma (LSCC)

Biomedicine & Pharmacotherapy, 2014
microRNAs, a family of small non-coding RNAs, involve in the pathogenesis of several types of cancers, including laryngeal squamous cell carcinoma (LSCC). MiR-370 is frequently aberrant expressed in various types of human cancer including LSCC. However, the role for miR-370 in LSCC remains elusive.
Wu, Yungang, Li, Xiaoyu, Taizhong, Pang, Li, Wenming, Xinliang, Pan   +4 more
openaire   +2 more sources

Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p

BMC Cancer, 2019
Background Glutamate metabotropic receptors (GRM) play a variety of roles in neuronal cells. However, their clinical significance and biological functions in breast cancer remain unknown. Methods RNA sequencing data of breast cancer was obtained from the
Bin Xiao, Daxiang Chen, Quan Zhou, Jianfeng Hang, Weiyun Zhang, Zhenzhan Kuang, Zhaohui Sun, Linhai Li   +7 more
doaj   +1 more source

MiR‑370 inhibits the oxidative stress and apoptosis of cardiac myocytes induced by hydrogen peroxide by targeting FOXO1

Experimental and Therapeutic Medicine, 2019
Myocardial infarction, one of the main factors that threatens human health, leads to cardiac cell death. Myocardial cells suffer ischemia and hypoxia for a long period of time, which can lead to irreversible cell death or apoptosis and cardiac dysfunction.
Qiu, Zhanjun, Wang, Lei, Mao, Huaiyu, Xu, Feng, Sun, Bin, Lian, Xinbao, Wang, Jiali, Kong, Feng, Wang, Lina, Chen, Yuguo   +9 more
openaire   +3 more sources

miR-146a and miR-370 coordinate enterovirus 71-induced cell apoptosis through targeting SOS1 and GADD45

, 2017
Enterovirus 71 (EV71) is an emerging life-threatening pathogen particularly in the Asia-Pacific region. The major pathogenic feature in EV71-infected cells is apoptosis.
何炳慶;俞松良;楊泮池, Chang, Ya-Ling;Ho, Bing-Ching;Sher, Singh;Yu, Sung-Liang;Yang, Pan-Chyr   +1 more
core   +1 more source

Table_2_Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway.XLSX

, 2022
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) contribute to myocardial ischemia/reperfusion (I/R) injury. However, the underlying mechanisms by which lncRNAs modulate myocardial I/R injury have not been thoroughly examined and ...
Deqiang Sun (447563), Deling Yin (352359), Fan Yu (513775), Jingsi Duan (11589211), Yao Tang (743479), Mingrui Li (2567635), Ting Zhong (564794), Xinbin Zheng (13772305), Yaxiu Liu (13772308)   +8 more
core   +1 more source

Circular RNA circ_0003204 inhibits proliferation, migration and tube formation of endothelial cell in atherosclerosis via miR-370-3p/TGFβR2/phosph-SMAD3 axis

Journal of Biomedical Science, 2020
Background Circular RNAs (circRNAs) represent a class of non-coding RNAs (ncRNAs) which are widely expressed in mammals and tissue-specific, of which some could act as critical regulators in the atherogenesis of cerebrovascular disease.
Shanchao Zhang, Guixiang Song, Jing Yuan, Shan Qiao, Shan Xu, Zhihua Si, Yang Yang, Xuxu Xu, Aihua Wang   +8 more
doaj   +1 more source

Data_Sheet_1_Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway.ZIP

, 2022
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) contribute to myocardial ischemia/reperfusion (I/R) injury. However, the underlying mechanisms by which lncRNAs modulate myocardial I/R injury have not been thoroughly examined and ...
Deqiang Sun (447563), Deling Yin (352359), Fan Yu (513775), Jingsi Duan (11589211), Yao Tang (743479), Mingrui Li (2567635), Ting Zhong (564794), Xinbin Zheng (13772305), Yaxiu Liu (13772308)   +8 more
core   +1 more source

MOESM8 of CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling

, 2019
Additional file 8: Figure S7. Either overexpression of RUVBL1 or inhibition of miR-370-3p partially restored the phenotypes caused by the circMYO10 knockdown.
Shengyu Wang (306423), Jianjun Ma (158111), Yute Yang (5463545), Gang Liu (81776), Yizheng Wu (1665766), Panyang Shen (7587599), Junxin Chen (2951379), Xiangqian Fang (6050843), Shuai Chen (506142), Shuying Shen (6050849), Shunwu Fan (4411273), Hongfei Wu (470334), Yifan Fang (7587602), Ziang Xie (3743974)   +13 more
core   +1 more source