Results 11 to 20 of about 336,133 (179)

circRNA_101277 Influences Cisplatin Resistance of Colorectal Cancer Cells by Modulating the miR-370/IL-6 Axis [PDF]

Genetics Research, 2022
Background. Colorectal cancer (CRC) is among the most prevalent malignancies globally. Early detection of precancerous lesions through routine colonoscopy has led to a dramatic reduction in CRC-related incidence and mortality among those between the ages
Qing Lv, Qinghua Xia, Anshu Li, Zhiyong Wang   +3 more
doaj   +3 more sources

CircRNA_1809 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells through miR-370-3p [PDF]

Scientific Reports
Circular RNA (circRNA) is a unique closed ring structure of noncoding RNA. Although many human diseases have been confirmed to be inextricably linked with circRNAs, whether circRNAs have a potential regulatory function in the osteogenic differentiation ...
Lei Zhang, Yidan Xu, Ningning Liu, Mengjie Xu, Refeina Tuerxun, Mireyeti Shahatibieke, Yuan Yao   +6 more
doaj   +3 more sources

miR-370 Expression Analysis in Breast Cancer

مجله دانشکده پزشکی اصفهان, 2015
Background: MicroRNAs (MiRNAs) are 21-24 nucleotides which have different levels of expression between tumors and normal tissues. In this study, we analyzed the expression level of miR-370 in different stages and grades of human breast cancer tissues ...
Halimeh Mollainezhad, Nahid Eskandari, Abbasali Pourazar, Alireza Andalib, Mansoor Salehi, Mazdak Ganjalikhani-Hakemi   +5 more
doaj   +2 more sources

MiR-370-3p regulate TLR4/SLC7A11/GPX4 to alleviate the progression of glucocorticoids-induced osteonecrosis of the femoral head by promoting osteogenesis and suppressing ferroptosis [PDF]

Journal of Orthopaedic Translation
Objectives: Osteonecrosis of the femoral head (ONFH) represents a severe complication of glucocorticoids (GCs) therapy in clinical settings. MicroRNAs (miRNAs) are critically involved in the progression of GCs-induced ONFH, with ferroptosis playing a ...
Rongtai Zuo, Bojun Cao, Lingchi Kong, Feng Wang, Shanyu Li, Haojie Shan, Junjie Guan, Qinglin Kang   +7 more
doaj   +2 more sources

CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis. [PDF]

Aging (Albany NY), 2021
Metastasis is the leading cause of breast cancer (BC)-related deaths. Circular RNAs (circRNAs) have emerged as essential regulators for cancer progression and metastasis. Therefore, the objective of this study was to investigate the role of circRNAs in BC metastasis and related mechanism.
Zhang W, Liu H, Jiang J, Yang Y, Wang W, Jia Z.   +5 more
europepmc   +4 more sources

Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells [PDF]

Scientific Reports, 2023
Endothelial dysfunction and inflammatory immune response trigger dedifferentiation of vascular smooth muscle cells (SMCs) from contractile to synthetic phenotype and initiate arterial occlusion.
Yerin Kim, Namhee Yu, Ye Eun Jang, Eunkyung Lee, Yeonjoo Jung, Doo Jae Lee, W. Robert Taylor, Hanjoong Jo, Jaesang Kim, Sanghyuk Lee, Sang Won Kang   +10 more
doaj   +2 more sources

CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis [PDF]

Cardiovascular Therapeutics, 2022
Background. Circular RNA Transformation/Transcription Domain Associated Protein (circTRRAP, hsa_circ_0081241) was abnormally upregulated in acute myocardial infarction (AMI) patients. However, its biological role and functional mechanism in AMI remain to
Yuan Zhang, Zhenggong Li, Jiao Wang, Hao Chen, Rui He, Hongkun Wu   +5 more
doaj   +2 more sources

Chi-miR-370-3p regulates hair follicle morphogenesis of Inner Mongolian cashmere goats. [PDF]

G3 (Bethesda), 2021
Abstract MicroRNAs (miRNAs), a class of 22 nucleotide (nt) noncoding RNAs, negatively regulate mRNA posttranscriptional modification in various biological processes. Morphogenesis of skin hair follicles in cashmere goats is a dynamic process involving many key signaling molecules, but the associated cellular biological mechanisms induced
Hai E, Han W, Wu Z, Ma R, Shang F, Wang M, Liang L, Rong Y, Pan J, Wang Z, Wang R, Su R, Zhao Y, Liu Z, Wang Z, Li J, Zhang Y.   +16 more
europepmc   +5 more sources

miR-370 mimic inhibits replication of Japanese encephalitis virus in glioblastoma cells

Neuropsychiatric Disease and Treatment, 2016
Wenjuan Li,1 Peng Cheng,2 Shangdan Nie,1 Wen Cui1 1School of Forensic and Laboratory Medicine, Jining Medical University, 2Shandong Academy of Medical Sciences, Shandong Institute of Parasitic Diseases, Jining, People’s Republic of ...
Li W, Cheng P, Nie S, Cui W
doaj   +4 more sources

Inhibition of intervertebral disc disease progression via the circPKNOX1-miR-370-3p-KIAA0355 axis. [PDF]

Cell Death Discov, 2021
AbstractThe molecular mechanism underlying the development of intervertebral disc disease (IVDD) is not completely understood. Circular RNAs (circRNAs) play a significant role in the occurrence and development of various diseases, and studies have shown that circPKNOX1 is involved in the compensatory response of extracellular matrix synthesis and ...
Huang Y, Gao J, Wang J, Ye H, Yao T, Xu Y, Chen Z, Shen S, Ma J.   +8 more
europepmc   +5 more sources