Silencing of miR-370 in human cholangiocarcinoma by allelic loss and interleukin-6 induced maternal to paternal epigenotype switch. [PDF]
Cholangiocarcinoma (CCA) is a highly lethal malignant tumor arising from the biliary tract epithelium. Interleukin-6 (IL-6) is a major mediator of inflammation and contributor to carcinogenesis within the biliary tree.
Fangmei An +11 more
doaj +1 more source
The non-coding landscape of head and neck squamous cell carcinoma. [PDF]
Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease marked by frequent recurrence and metastasis and stagnant survival rates. To enhance molecular knowledge of HNSCC and define a non-coding RNA (ncRNA) landscape of the disease, we ...
Grandis, Jennifer R +17 more
core +5 more sources
Correlation Between Endoglin and Malignant Phenotype in Human Melanoma Cells: Analysis of hsa-mir-214 and hsa-mir-370 in Cells and Their Extracellular Vesicles. [PDF]
Endoglin (CD105) is an auxiliary receptor of transforming growth factor (TGF)-β family members that is expressed in human melanomas. It is heterogeneously expressed by primary and metastatic melanoma cells, and endoglin targeting as a therapeutic ...
Bernabeu, Carmelo +7 more
core +2 more sources
Cerebral ischemia reperfusion (CIR) is one of the highly lethal diseases in the world. MicroRNA‐370 (miR‐370) exerts multiple functions in different diseases. However, further research is needed to investigate the potential role of miR‐370 in CIR injury.
Zhong‐Fan Ruan +5 more
doaj +1 more source
Purpose Long non-coding RNAs (lncRNAs) play important roles in the development of pneumonia. We aimed to explore the role of the lncRNA KCNQ1OT1 in pneumonia and its underlying mechanisms.
Ping Wang +3 more
doaj +1 more source
miR‐370 is stage‐specifically expressed during mouse embryonic development and regulates Dnmt3a [PDF]
MicroRNAs (miRNAs) are small non‐coding RNAs that participate in a large variety of biological processes. In this paper, the spatiotemporal expression pattern of miR‐370 was characterized during mouse embryonic development, and was found to be stage‐ and tissue‐specifically expressed.
Qi, Liu +7 more
openaire +2 more sources
circ_0023461 Silencing Protects Cardiomyocytes from Hypoxia-Induced Dysfunction through Targeting miR-370-3p/PDE4D Signaling. [PDF]
Background. Acute myocardial infarction (AMI) is a common cardiovascular disease with high disability and mortality. Circular RNAs (circRNAs) are implicated in the pathomechanism of multiple human diseases, including AMI. This study intended to explore the function and working mechanism of a novel circRNA circ_0023461 in hypoxia‐induced cardiomyocytes.
Ren K +7 more
europepmc +4 more sources
Interaction of miRNA-370-3p and the AKT/Foxo1 pathway in trophoblast cells in gestational diabetes mellitus [PDF]
Background and aims: Gestational diabetes mellitus (GDM) is one of the most common clinical pregnant diseases with. miRNAs participate in a variety of biological functions as well as the pathogenesis of GDM. Previously, our group found by qPCR miR-370-3p
Ji, Jinlu
core
MiR-370-5p inhibits the progression of breast cancer via targeting LUC7L3
Breast cancer is one of the most common malignancies and one of the leading causes of cancer-induced mortality among women. Over the past decades, the occurrence of breast cancer has been a significant increase. As documented in numerous researches, microRNAs (miRNAs) play vital roles in a wide range of biological processes associated with the ...
Kai, Sang +5 more
openaire +2 more sources
It has been reported that PAQR4 (Progestin and AdipoQ Receptor 4) expression is closely associated with progression of many cancers and microRNA (miRNA) processing.
Ye Feng +5 more
doaj +1 more source

