Results 51 to 60 of about 11,229 (247)
The role of miR-370 in fibrosis after myocardial infarction
Molecular Medicine Reports, 2017 In the present study, we investigated the expression of miR‑370 in the border area of infarction after myocardial infarction and its role in the process of post‑infarction fibrosis. A myocardial infarction model in Sprague-Dawley rats was established. After two weeks, the mRNA levels of transforming growth factor‑β1 (TGFβ1), TGFβRII, ColIa1, ColIIIa1 ...
Yuan, Hui, Gao, Jie
openaire +3 more sources
Circulating micrornas associated with glycemic impairment and progression in Asian Indians. [PDF]
, 2015 Aims/hypothesisAsian Indians have a high incidence of type 2 diabetes, but factors associated with glycemic progression in this population are not understood.
Aouizerat, Bradley E +3 more
core +1 more source
MiR‑370 promotes apoptosis in colon cancer by directly targeting MDM4
Oncology Letters, 2017 MicroRNA (miR)-370 functions as a tumor suppressor or promoter in several cancers. However, the expression and biological role of miR-370 in colon cancer remains undefined. In the present study, miR-370 expression in both normal and malignant colon tissues was quantified by quantitative polymerase chain reaction.
Shen, Xiaogang +5 more
openaire +3 more sources
Experimental procedures to identify and validate specific mRNA targets of miRNAs [PDF]
, 2015 Functionally matured microRNAs (miRNAs) are small single-stranded non-coding RNA molecules which are emerging as important post-transcriptional regulators of gene expression and consequently are central players in many physiological and pathological ...
Elton, Terry S., Yalowich, Jack C.
core +1 more source
The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia
Molecular Cancer, 2012 Background Recent evidence has accumulated that MicroRNA (miRNA) dysregulation occurs in the majority of human malignancies including acute myeloid leukemia (AML) and may contribute to onco-/leukemo-genesis.
Zhang Xiaolu +8 more
doaj +1 more source
Immunity, Inflammation and Disease, 2023 Background Circular RNAs have emerged as important regulators in the pathogenesis of human diseases, including infantile pneumonia (IP). In this study, we aimed to explore the effects of circ_0035292 on lipopolysaccharide (LPS)‐treated Wistsar Institute (
Ying Guo, Zhouzhen Li, Chen Cheng
doaj +1 more source
Wnt7a and miR-370-3p: new contributors to bladder cancer invasion
Biotarget, 2018 In eukaryotes, microRNAs (miRNAs) are central regulators of gene expression. These small noncoding RNAs are about 19–24 nucleotides long (1). miRNAs can silence gene expression by binding to a complementary sequence in the 3'-UTR of the target gene, which then triggers mRNA degradation.
Danielle, Scheunemann +5 more
openaire +2 more sources
Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients [PDF]
, 2013 Exosomes are cellular secretory vesicles containing microRNAs (miRNAs). Once secreted, exosomes are able to attach to recipient cells and release miRNAs potentially modulating the function of the recipient cell.
Banigan, Meredith G. +11 more
core +11 more sources
Expression of microRNA-370 in human breast cancer compare with normal samples
Advanced Biomedical Research, 2016 Background: Breast cancer is the second leading cause of deaths from cancer in the woman. MicroRNAs (miRNAs) are endogenous noncoding RNAs that are known critical player in carcinogenesis. The role of miR-370 in malignancies remains controversial because
Halimeh Mollainezhad +4 more
doaj +1 more source
MiR-107 and miR-99a-3p predict chemotherapy response in patients with advanced colorectal cancer [PDF]
, 2017 Molina-Pinelo, Sonia et al.[Background] MicroRNAs (miRNAs) are involved in numerous biological and pathological processes including colorectal cancer (CRC).
Benavent, Marta +8 more
core +1 more source