Results 121 to 130 of about 47,292 (192)

Integrative bioinformatics analysis of miRNA and mRNA expression profiles and identification of associated miRNA-mRNA network in intracranial aneurysms

Non-coding RNA Research
Background: Intracranial aneurysms (IAs) represent protrusions in the vascular wall, with their growth and wall thinning influenced by various factors. These processes can culminate in the rupture of the aneurysm, leading to subarachnoid hemorrhage (SAH).
Dongxiao Xu, Ilgiz Gareev, Ozal Beylerli, Valentin Pavlov, Huang Le, Huaizhang Shi   +5 more
doaj   +1 more source

Benchmarking miRNA reference genes in B-cell precursor acute lymphoblastic leukemia

Scientific Reports
MicroRNAs (miRNAs) play dual roles in acute lymphoblastic leukemia (ALL) as both tumor suppressors and oncogenes, and miRNA expression profiles can be used for patient risk stratification.
Teresa Mack, Tommaso Gianferri, Alexandra Niedermayer, Klaus-Michael Debatin, Lüder H. Meyer, Vera Muench   +5 more
doaj   +1 more source

Exploring miRNA Biomarkers in Major Depressive Disorder: A Molecular Medicine Perspective

Current Issues in Molecular Biology
Major depressive disorder (MDD) is a complex mental health condition with a multifaceted and incompletely elucidated pathophysiology. MicroRNAs (miRNAs) have emerged as potential biomarkers due to their role in gene regulation and the observed ...
Cătălin Prodan-Bărbulescu, Laura Andreea Ghenciu, Edward Şeclăman, Georgeta Cristiana Bujor, Virgil Enătescu, Alexandra-Ioana Danila, Ecaterina Dăescu, Luminioara Maria Rosu, Ionuţ Flaviu Faur, Paul Tuţac, Norberth-Istvan Varga, Tanasescu Sonia, Ciprian Duță   +12 more
doaj   +1 more source

Identifying the Potential Differentially Expressed miRNAs and mRNAs in Osteonecrosis of the Femoral Head Based on Integrated Analysis

Clinical Interventions in Aging, 2021
Yangquan Hao, Chao Lu, Baogang Zhang, Zhaochen Xu, Hao Guo, Gaokui Zhang Department of Osteonecrosis and Joint Reconstruction, Honghui Hospital Xian Jiao Tong University Health Science Center, Xian, Shaanxi 710068, People’s Republic of ...
Hao Y, Lu C, Zhang B, Xu Z, Guo H, Zhang G   +5 more
doaj  

Comparative transcriptome and microRNA profiles of equine mesenchymal stem cells, fibroblasts, and their extracellular vesicles [PDF]

Background: Mesenchymal stem cells (MSCs) are a promising tool in regenerative medicine due to their ability to secrete paracrine factors that modulate tissue repair. Extracellular vesicles (EVs) released by MSCs contain bioactive molecules (e.g., mRNAs,
Bochenek, Michał, Bugno-Poniewierska, Monika, Gurgul, Artur, Karnas, Elżbieta, Sawicki, Sebastian, Semik-Gurgul, Ewelina, Szmatoła, Tomasz, Żurowski, Jakub   +7 more
core   +2 more sources

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia [PDF]

, 2017
et al.,, Uy, Geoffrey L
core   +2 more sources

MicroRNA profiling in women with migraine: effects of CGRP-targeting treatment

The Journal of Headache and Pain
Background Migraine lacks biomarkers that can trace the biological pathways of the disease and predict the effectiveness of treatments. Monoclonal antibodies targeting calcitonin gene-related peptide pathway – including erenumab – offer the opportunity ...
Raffaele Ornello, Veronica Zelli, Chiara Compagnoni, Valeria Caponnetto, Eleonora De Matteis, Cindy Tiseo, Alessandra Tessitore, Simona Sacco   +7 more
doaj   +1 more source

Overexpression of circular RNA hsa_circ_0008621 facilitates colorectal cancer progression and predicts poor prognosis

Annals of Gastroenterological Surgery
Aim To evaluate the potential role of serum and tissue hsa_circ_0008621 as a prognostic biomarker for CRC patients. Focused on the functional role of hsa_circ_0008621 in colorectal cancer (CRC).
Xiaohu Zhou, Lei Wu, Chunyan Tian
doaj   +1 more source

Serum microRNAs as biomarker for active and latent tuberculosis infection in immunocompetent and immunodeficient hosts [PDF]

, 2015
Background: Expression patterns of microRNAs in body fluids show potential to be used as noninvasive rapid and accurate biomarkers for various diseases.The study aimed to (i) identify patterns of microRNA signatures for diagnosis of tuberculosis (TB) and
Mwangoka, Grace Wynn
core  

Target prediction and functional validation of MicroRNA for coagulation factor V and TFPI in liver cancer [PDF]

, 2019
Background: The connection between cancer and increased risk of thrombosis is well established and liver cancer (HCC) patients have been found to have an increased risk of thrombosis.
Skogstrøm, Katarina Baumgarten
core