Non-coding RNA ResearchBackground: Intracranial aneurysms (IAs) represent protrusions in the vascular wall, with their growth and wall thinning influenced by various factors. These processes can culminate in the rupture of the aneurysm, leading to subarachnoid hemorrhage (SAH).
Dongxiao Xu +5 more
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Analysis of ANRIL gene polymorphism rs4977574 association with kidney cancer development in Ukrainian population. [PDF]
, 2020 ANRIL (Antisense Non-coding RNA in the INK4 Locus, also known as CDKN2B-AS1) – 3.8-kb long non-coding RNA transcribed from the antisense strand of INK4b-ARF-INK4a gene cluster.
Ataman, A. V. +2 more
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Benchmarking miRNA reference genes in B-cell precursor acute lymphoblastic leukemia
Scientific ReportsMicroRNAs (miRNAs) play dual roles in acute lymphoblastic leukemia (ALL) as both tumor suppressors and oncogenes, and miRNA expression profiles can be used for patient risk stratification.
Teresa Mack +5 more
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Exploring miRNA Biomarkers in Major Depressive Disorder: A Molecular Medicine Perspective
Current Issues in Molecular BiologyMajor depressive disorder (MDD) is a complex mental health condition with a multifaceted and incompletely elucidated pathophysiology. MicroRNAs (miRNAs) have emerged as potential biomarkers due to their role in gene regulation and the observed ...
Cătălin Prodan-Bărbulescu +12 more
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Frontiers in Cell and Developmental BiologyMicroplastics (MPs) are increasingly implicated in cancer biology through effects on gene expression, stress responses, and treatment susceptibility; however, causal links remain provisional.
Akmaral Baspakova +13 more
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Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia [PDF]
, 2017 et al.,, Uy, Geoffrey L
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Cukurova Medical JournalPurpose: This study aims to investigate the expression profiles of hsa_circ_0025244 and hsa_circ_0001546 in breast tissue samples and to propose potential regulatory axes for these circular RNAs. Materials and Methods: The expression levels of hsa_circ_0025244 and hsa_circ_0001546 were determined in 55 tumor tissue samples (30 Luminal B and 25 Luminal
Fahrünnisa Abanoz +5 more
openaire +1 more source
Comparative transcriptome and microRNA profiles of equine mesenchymal stem cells, fibroblasts, and their extracellular vesicles [PDF]
Background: Mesenchymal stem cells (MSCs) are a promising tool in regenerative medicine due to their ability to secrete paracrine factors that modulate tissue repair. Extracellular vesicles (EVs) released by MSCs contain bioactive molecules (e.g., mRNAs,
Bochenek, Michał +7 more
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MicroRNA profiling in women with migraine: effects of CGRP-targeting treatment
The Journal of Headache and PainBackground Migraine lacks biomarkers that can trace the biological pathways of the disease and predict the effectiveness of treatments. Monoclonal antibodies targeting calcitonin gene-related peptide pathway – including erenumab – offer the opportunity ...
Raffaele Ornello +7 more
doaj +1 more source
Serum microRNAs as biomarker for active and latent tuberculosis infection in immunocompetent and immunodeficient hosts [PDF]
, 2015 Background: Expression patterns of microRNAs in body fluids show potential to be used as noninvasive rapid and accurate biomarkers for various diseases.The study aimed to (i) identify patterns of microRNA signatures for diagnosis of tuberculosis (TB) and
Mwangoka, Grace Wynn
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