Results 91 to 100 of about 319,034 (267)
Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes. [PDF]
, 2013 AIMS/HYPOTHESIS: MicroRNAs are key regulators of gene expression involved in health and disease. The goal of our study was to investigate the global changes in beta cell microRNA expression occurring in two models of obesity-associated type 2 diabetes ...
Guay, C. +7 more
core +2 more sources
MicroRNAs as potential biomarkers in pituitary adenomas [PDF]
, 2021 Pituitary adenomas (PAs) are one of the most common lesions of intracranial neoplasms, occurring in approximately 15% of the general population. They are typically benign, although some adenomas show aggressive behavior, exhibiting rapid growth, drug ...
Aurilia, C. +6 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Deregulation of the imprinted DLK1-DIO3 locus ncRNAs is associated with replicative senescence of human adipose-derived stem cells [PDF]
, 2018 Background Human adult adipose-derived stem cells (hADSCs) have become the most promising cell source for regenerative medicine. However the prolonged ex vivo expansion periods required to obtain the necessary therapeutic dose promotes progressive ...
Albo-Castellanos, Carmen +7 more
core +6 more sources
Genetic networks in Parkinson's and Alzheimer's disease [PDF]
, 2020 Parkinson\u27s disease (PD) and Alzheimer\u27s disease (AD) are the most common neurodegenerative diseases and there is increasing evidence that they share common physiological and pathological links.
Carroll, Camilla +4 more
core +3 more sources
Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas +7 more
wiley +1 more source
The emerging role of non-coding RNAs in pituitary gland tumors and meningioma [PDF]
, 2021 Simple Summary Non-coding RNAs have been recently attained attention because of their contribution in the pathogenesis of brain tumors. These transcripts have been shown to be dysregulated in pituitary gland tumors as well as meningiomas.
Abak, Atefe +4 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
The roles of ING5 in cancer: A tumor suppressor
Frontiers in Cell and Developmental Biology, 2022 As a Class II tumor suppressor, ING5 contains nuclear localization signal, plant homeodomain, novel conserved region, and leucine zipper-like domains. ING5 proteins form homodimer into a coil-coil structure, and heterodimers with ING4, histone H3K4me3 ...
Hua-chuan Zheng, Hang Xue, Hua-mao Jiang
doaj +1 more source
FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee +7 more
wiley +1 more source