miR-590-3p Is a Novel MicroRNA in Myocarditis by Targeting Nuclear Factor Kappa-B in vivo
Cardiology, 2015 <b><i>Objective:</i></b> Nuclear factor kappa-B (NF-κB)-induced inflammation leads to myocarditis and heart dysfunction. How microRNAs (miRNAs) contribute to this process is poorly defined. The aim of this study was to investigate whether miRNAs regulate NF-κB-induced inflammation in experimental autoimmune ...
Xiao-Zhen Zhuo +11 more
openaire +3 more sources
ATF-3/miR-590/GOLPH3 signaling pathway regulates proliferation of breast cancer
BMC Cancer, 2018 Background Breast cancer is one of the leading causes of death in women worldwide. Fast growth is the important character of breast cancer, which makes sure the subsequent metastasize and invasion breast cancer.
Qiong Song +8 more
doaj +1 more source
Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors
Journal of Immunology Research, 2022 Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou +7 more
doaj +1 more source
Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome
Frontiers in Cell and Developmental Biology, 2021 Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno +3 more
doaj +1 more source
The Effect of Chemotherapy in Gestational Trophoblastic Disease on Infertility: A Review on Pathophysiologic Mechanism [PDF]
, 2021 Today, young women infertility through chemotherapy has become a global challenge. Chemotherapy destructs the malignant cells by reactive oxygen species (ROS) production and inflammatory factors secretion; these factors can also destruct the ovarian and ...
Ebrahimi, Maryam +5 more
core +2 more sources
Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility
Non-Coding RNA, 2023 Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been identified in different tumors and are associated with cancer.
Iael Weissberg Minutentag +10 more
doaj +1 more source
Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation [PDF]
, 2019 Loss of functional cardiomyocytes is a major determinant of heart failure after myocardial infarction. Previous high throughput screening studies have identified a few microRNAs (miRNAs) that can induce cardiomyocyte proliferation and stimulate cardiac ...
Ali, Hashim +15 more
core +4 more sources
The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells. [PDF]
, 2014 Dendritic cells (DCs) are professional APCs that have a role in the initiation of adaptive immune responses and tolerance. Among the tolerogenic mechanisms, the expression of the enzyme IDO1 represents an effective tool to generate T regulatory cells. In
Ciciarello, M. +12 more
core +2 more sources
Effect of LINC00657 on Apoptosis of Breast Cancer Cells by Regulating miR-590-3p
Cancer Management and Research, 2020 Qiuli Shan,1 Fan Qu,1 Weiping Yang,2 Ningning Chen1 1College of Biological Science and Technology, University of Jinan, Jinan 250022, People’s Republic of China; 2Department of Thyroid Breast Surgery, Qingdao Chengyang People’s Hospital ...
Shan Q, Qu F, Yang W, Chen N
doaj
Unique, Gender-Dependent Serum microRNA Profile inPLS3 Gene-Related Osteoporosis [PDF]
, 2020 Plastin 3 (PLS3), encoded byPLS3, is a newly recognized regulator of bone metabolism, and mutations in the encoding gene result in severe childhood-onset osteoporosis.
Alice Costantini +11 more
core +1 more source