Results 121 to 130 of about 4,830 (194)

Temozolomide resistance in glioblastoma: a non-coding RNA viewpoint

Advances in Cancer Biology - Metastasis
As an imidazotetrazine derived from the alkylating substance dacarbazine, Temozolomide (TMZ) is commonly used as the routine chemotherapy for new cases of glioblastoma multiforme (GBM). It substantially improves the clinical outcome of patients.
Maryam Motallebinezhad, Ali Faravash, Mohammad Ghasemian, Zahra Tajik, Mohsen Ahmadi, Solat Eslami, Soudeh Ghafouri-Fard   +6 more
doaj   +1 more source

miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions.

PLoS ONE, 2018
Arsenic, a naturally occurring element, contaminates the drinking water of over 200 million people globally. Chronic arsenic exposure causes multiple cancers including those originating from skin, lung and bladder, and is associated with liver, kidney ...
Laila Al-Eryani, Samantha F Jenkins, Vanessa A States, Jianmin Pan, Janine C Malone, Shesh N Rai, Susan Galandiuk, Ashok K Giri, J Christopher States   +8 more
doaj   +1 more source

A novel integrated miRNA–donor age signature enables detection of cardiac allograft vasculopathy

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
Irene González‐Torrent, Carlota Benedicto, Marta Delgado‐Arija, Lorena Pérez‐Carrillo, Isaac Giménez‐Escamilla, Estefanía Tarazón, Esther Roselló‐Lletí   +6 more
wiley   +1 more source

The Role of miR-590-3p in Regulating Human Epithelial Ovarian Cancer Development [PDF]

, 2019
Epithelial ovarian cancer (EOC) has the highest mortality rate among all gynecological malignancies. Early detection and intervention remain key to patient prognosis fueling the search for reliable biomarkers. MicroRNAs (miRNAs) are small non-coding RNAs
Salem, Mohamed
core  

miRNA expression profile of vulvar squamous cell carcinoma and identification of the oncogenic role of miR-590-5p

Oncology Reports, 2015
MicroRNAs (miRNAs), a class of small non-coding RNA molecules, are associated with a variety of human cancers. Currently, little data are available regarding miRNA expression in vulvar squamous cell carcinoma (VSCC); the mechanism of action of miRNAs in VSCC still requires investigation.
Xiuhua, Yang, Xin, Wu
openaire   +3 more sources

Exosomal microRNAs from Longitudinal Liquid Biopsies for the Prediction of Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients: A Proof of Concept SIOPEN Study [PDF]

, 2019
Despite intensive treatment, 50% of children with high-risk neuroblastoma (HR-NB) succumb to their disease. Progression through current trials evaluating the efficacy of new treatments for children with HR disease usually depends on an inadequate ...
Bosco, MC, Burchill, S, Cangelosi, D, Carlini, B, Castellano, A, Cañete, A, Conte, M, Corrias, MV, Eva, A, Font de Mora, J, Fruci, D, Garaventa, A, Ladenstein, R, Luksch, R, Marimpietri, D, Mazzocco, K, Morini, M, Pezzolo, A, Raggi, F, Schleiermacher, G, Segalerba, D, Sementa, AR, Varesio, L, Viprey, V, Yáñez, Y   +24 more
core   +1 more source

Integrative bioinformatics analysis of miRNA and mRNA expression profiles and identification of associated miRNA-mRNA network in intracranial aneurysms

Non-coding RNA Research
Background: Intracranial aneurysms (IAs) represent protrusions in the vascular wall, with their growth and wall thinning influenced by various factors. These processes can culminate in the rupture of the aneurysm, leading to subarachnoid hemorrhage (SAH).
Dongxiao Xu, Ilgiz Gareev, Ozal Beylerli, Valentin Pavlov, Huang Le, Huaizhang Shi   +5 more
doaj   +1 more source

Circulating miRNA Profiling in Plasma Samples of Ovarian Cancer Patients [PDF]

, 2019
L
Lukács, János, Márton, Éva, Nagy, Bálint, Penyige, András, Póka, Róbert, Soltész, Beáta, Szilágyi, Melinda, Széles, Lajos   +7 more
core   +1 more source

Prognostic and predictive microRNA panels for heart failure patients with reduced or preserved ejection fraction: a meta-analysis of Kaplan–Meier-based individual patient data

BMC Medicine
Background Cardiac troponins and natriuretic peptides are benchmark biomarkers for heart failure (HF) with reduced ejection fraction (HFrEF) but have limited prognostic performance for HF patients with preserved ejection fraction (HFpEF).
Reza Parvan, Victoria Becker, Milad Hosseinpour, Yousef Moradi, William E. Louch, Alessandro Cataliotti, Yvan Devaux, Michael Frisk, Gustavo Jose Justo Silva, AtheroNET COST Action CA21153   +9 more
doaj   +1 more source

MicroRNA miR-590-5p inhibits breast cancer cell stemness and metastasis by targeting SOX2.

European review for medical and pharmacological sciences, 2017
SOX2 (Sry-related high-mobility box SOX-2) is a transcription factor, which is essential for maintaining the cancer cell stemness. However, the role of microRNAs targeting  SOX2 in cancer cell stemness remains unclear. We examined the effect of miR-590-5p, which targeted  SOX2, on the breast cancer cell stemness and metastasis.We predicted and screened
L, Zhou, L-C, Zhao, N, Jiang, X-L, Wang, X-N, Zhou, X-L, Luo, J, Ren   +6 more
openaire   +1 more source