Results 101 to 110 of about 276,038 (194)

miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions.

PLoS ONE, 2018
Arsenic, a naturally occurring element, contaminates the drinking water of over 200 million people globally. Chronic arsenic exposure causes multiple cancers including those originating from skin, lung and bladder, and is associated with liver, kidney ...
Laila Al-Eryani, Samantha F Jenkins, Vanessa A States, Jianmin Pan, Janine C Malone, Shesh N Rai, Susan Galandiuk, Ashok K Giri, J Christopher States   +8 more
doaj   +1 more source

Integrative bioinformatic and clinical validation reveals dynamic regulation of circulating microRNAs before and after antiretroviral therapy in HIV-positive patients

Scientific Reports
MicroRNAs (miRNAs) play a crucial role in gene regulation, including HIV, where they influence viral replication and immune response. This study aims to identify key miRNAs involved in HIV pathogenesis, using bioinformatics and cohort validation to ...
Haktan Sonmez, Zofia Wicik, Ceren Eyileten, Sara Ahmadova, Ömer Fehmi Tabak, Bilgul Mete, Ilker Inanc Balkan, Oner Suzer, Andleeb Shahzadi   +8 more
doaj   +1 more source

miR-708-5p inhibited STK4-mediated Hippo-YAP1 signaling pathway.

, 2022
(A) The targeting sequence of miR-708-5p in the 3’UTR of STK4 was predicated using Starbase (http://starbase.sysu.edu.cn/index.php). (B) The interaction between miR-708-5p and STK4 was identified using dual-luciferase reporter assay.
Hongyu Liang (201342), Yu Ren (428662), Xiao Wang (19312), Yuzhen Ma (546790)   +3 more
core   +1 more source

Tumor-educated platelet miR-34c-3p and miR-18a-5p as potential liquid biopsy biomarkers for nasopharyngeal carcinoma diagnosis

, 2019
Hui Wang,1 Xiuqi Wei,1 Bian Wu,2 Jingyu Su,1 Wenbin Tan,3 Kunyu Yang21Department of Laboratory Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, People’s Republic of China; 2Cancer Center,
Tan W, Yang K, Wu B, Wei X, Wang H, Su J
core  

miR-483-5p and incident cardiovascular disease.

, 2018
miR-483-5p and incident cardiovascular disease.
Widet Gallo (4533472), Lena Eliasson (73900), Olle Melander (25955), Jonathan Lou S. Esguerra (225381)   +3 more
core   +1 more source

Integrative bioinformatics analysis of miRNA and mRNA expression profiles and identification of associated miRNA-mRNA network in intracranial aneurysms

Non-coding RNA Research
Background: Intracranial aneurysms (IAs) represent protrusions in the vascular wall, with their growth and wall thinning influenced by various factors. These processes can culminate in the rupture of the aneurysm, leading to subarachnoid hemorrhage (SAH).
Dongxiao Xu, Ilgiz Gareev, Ozal Beylerli, Valentin Pavlov, Huang Le, Huaizhang Shi   +5 more
doaj   +1 more source

miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA

, 2018
Xuehua Yang, Jianwei Qiu, Haifeng Kang, Yaming Wang, Junbo Qian Department of Gastroenterology, The Second Affiliated Hospital of Nantong University, Nantong, Jiangsu, China Background: MiR-125a-5p has been reported to be involved in the development and
Yang X, Qiu J, Kang H, Qian J, Wang Y
core  

Prognostic and predictive microRNA panels for heart failure patients with reduced or preserved ejection fraction: a meta-analysis of Kaplan–Meier-based individual patient data

BMC Medicine
Background Cardiac troponins and natriuretic peptides are benchmark biomarkers for heart failure (HF) with reduced ejection fraction (HFrEF) but have limited prognostic performance for HF patients with preserved ejection fraction (HFpEF).
Reza Parvan, Victoria Becker, Milad Hosseinpour, Yousef Moradi, William E. Louch, Alessandro Cataliotti, Yvan Devaux, Michael Frisk, Gustavo Jose Justo Silva, AtheroNET COST Action CA21153   +9 more
doaj   +1 more source

miR-379-5p promotes ovarian granulosa cell apoptosis in primary ovarian insufficiency by targeting KNDC1 and PEG10

Frontiers in Genetics
BackgroundPrimary ovarian insufficiency (POI) is a heterogeneous disorder characterized by premature decline in ovarian function in women of reproductive age, yet its molecular mechanisms remain incompletely elucidated.
Jie Luo, Jie Luo, Fan Zhang, Yurong Feng, Fang You, Daobin Yang, Zengguang Wu, Li Zeng, Li Zeng   +8 more
doaj   +1 more source

Long Non-Coding RNA Linc-USP16 Functions As a Tumour Suppressor in Hepatocellular Carcinoma by Regulating PTEN Expression

Cellular Physiology and Biochemistry, 2017
Background/Aims: Recent evidence has indicated the crucial regulatory roles of long non-coding RNAs (lncRNAs) in tumour biology. In hepatocellular carcinoma (HCC), aberrant expression of lncRNAs plays an essential role in HCC tumourigenesis. However, the
Jidong Sui, Xuejun Yang, Wenjing Qi, Kun Guo, Zhenming Gao, Liming Wang, Deguang Sun   +6 more
doaj   +1 more source