Results 91 to 100 of about 4,830 (194)

Gallic Acid‐Responsive microRNAs Reprogram Lignification During Drought Acclimation Process in Spearmint

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mentha spicata L. (spearmint) is a high‐value aromatic and medicinal species, whose productivity is strongly affected by water deficit. Nevertheless, the molecular mechanisms underlying drought acclimation in this mint remain largely unexplored. Thus, here, we investigated the microRNA‐mediated regulatory processes triggered in M.
Alessia D'Agostino, Gabriele Di Marco, Gerardo Pepe, Adelaide Teofani, Chiara Pontecorvi, Manuela Helmer‐Citterich, Antonella Canini, Angelo Gismondi   +7 more
wiley   +1 more source

Expression Profiles of Exosomal MicroRNAs from HEV- and HCV-Infected Blood Donors and Patients: A Pilot Study

Viruses, 2020
Exosomes seem to play an important role in hepatits C virus (HCV) and hepatitis E virus (HEV) infection by shielding their cargo from the host immune responses, with microRNAs being key exosomal components.
Karen McGowan, Kenneth J. Simpson, Juraj Petrik   +2 more
doaj   +1 more source

Identifying microRNA/mRNA dysregulations in ovarian cancer [PDF]

, 2012
Background MicroRNAs are a class of noncoding RNA molecules that co-regulate the expression of multiple genes via mRNA transcript degradation or translation inhibition.
A Berchuck, A Laios, AC Society, AK Godwin, C Rosty, CA Wilson, CP Masamha, D Botta, D Spentzos, D Ye, D Zhang, EJ Nam, el SA Arafa, Gregory D Miles, Gunaretnam Rajagopal, Gyan Bhanot, H Donninger, H Liu, H Yang, HC Dan, I Hoffmann, I Tamm, JB MacQueen, JM Lancaster, K Macleod, K Pearson, K Selvendiran, KH Lu, L Zhang, LC Hartmann, Lorna Rodriguez, M Seiler, MC Todd, Michael Seiler, MV Iorio, N Dahiya, P Li, PO Humbert, R Chekerov, R Siegel, S Ma, SK Wyman, T Raemaekers   +42 more
core   +2 more sources

MiR-590-5p regulates cell proliferation, apoptosis, migration and invasion in oral squamous cell carcinoma by targeting RECK.

Histology and histopathology, 2021
To discover the role of miR-590-5p in oral squamous cell carcinoma (OSCC) progression and the corresponding mechanism via the targeting RECK.OSCC (n=85) and normal oral tissues (n=60) were collected to quantify the miR-590-5p expression by using qRT-PCR.
Bao, Wei-Wei, Shi, You-Ling, Ma, Yan, Qu, Xing-Hui, Pang, Guang-Ming, Yang, Lei   +5 more
openaire   +2 more sources

Spectral Representation of Neurochemicals With Phase, Frequency Offset, and Lineshape Invariance: Application to JPRESS for In Vivo Concentration and T2 Mapping by Deep Learning

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3052-3064, June 2026.
ABSTRACT Purpose Using artificial intelligence neural networks to generate a representation that maps the input directly to neurochemical concentrations and metabolite‐level average transverse relaxation times (T2). Methods The proposed model used time‐domain JPRESS data as input and was trained to be invariant to phase shifts, frequency offsets, and ...
Yan Zhang, Jun Shen
wiley   +1 more source

Exosomal Non‐Coding RNAs in Gastrointestinal Cancer Drug Resistance: A Systematic Review of Emerging Mechanisms and Clinical Implications

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Gastrointestinal (GI) tumours are one of the most prevalent cancers globally. Even with normal GI function, individuals may develop neoplasms, highlighting the need to better understand the underlying causes of tumorigenesis. The emergence of tumour drug resistance represents the main reason for the failure of drug treatment; thus, it is ...
Mohsen Sharif‐zak, Zahra Sadeghloo, Fateme Binayi, Stefania Nobili, Sara Ashtari, Amir Sadeghi, Nayeralsadat Fatemi   +6 more
wiley   +1 more source

Tissue and circulating microRNAs as biomarkers of response to obesity treatment strategies [PDF]

, 2020
Background: Obesity, characterized by an increased amount of adipose tissue, is a metabolic chronic alteration which has reached pandemic proportion. Lifestyle changes are the first line therapy for obesity and a large variety of dietary approaches have ...
Catanzaro G., Ferretti E., Filardi T., Migliaccio S., Morano S., Sabato C., Vacca A.   +6 more
core   +1 more source

Circular RNA hsa_circ_0026344 suppresses gastric cancer cell proliferation, migration and invasion via the miR-590-5p/PDCD4 axis

Journal of Pharmacy and Pharmacology, 2022
Abstract Objectives Circular RNA (CircRNA) is a class of non-coding RNA transcripts, with multiple pathophysiological functions. Instead, the mechanism and function of circRNA in gastric cancer (GC) are not fully deciphered.
Long Lv, Jinghu Du, Daorong Wang, Zeqiang Yan   +3 more
openaire   +2 more sources

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

Advanced Science, Volume 13, Issue 24, 27 April 2026.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu, Lili Su, Shuiping Gao, Wenting Liu, Hongxia Wang   +4 more
wiley   +1 more source

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

Advanced Science, Volume 13, Issue 23, 23 April 2026.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu, Chenchen Zhu, Xuelin Yao, Yi Liu, Jing Zhu, Yuebo Li, Hanjie Xu, Cheng Peng, Ge Shan, Liang Chen, Ying Zhou   +10 more
wiley   +1 more source