Results 181 to 190 of about 3,028 (210)

Maternal-fetal microRNA axis in congenital heart disease: implications for tetralogy of Fallot. [PDF]

Front Cardiovasc Med
Calcaterra V, Gervasoni C, Ceriani C, Mannarino S, Lanzotti A, Puricelli F, Raso I, Maugeri P, Bertoli G, Zuccotti G.   +9 more
europepmc   +1 more source

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JHDM1D-AS1-driven inhibition of miR-940 releases ARTN expression to induce breast carcinogenesis

Clinical and Translational Oncology, 2023
As ceRNA network of long non-coding RNA (lncRNA)-microRNA (miR)-messenger RNAs (mRNA) can be predicted on the basis of bioinformatics tools, we are now one step closer to deeper understanding carcinogenic mechanisms. In this study, we clarified the mechanistic understanding of JHDM1D-AS1-miR-940-ARTN ceRNA network in the development of breast cancer ...
Yonggang Zuo, Mingde Ma, Yuqing Wen, Liang Chang, Changping Qu   +4 more
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miR-940 regulates the inflammatory response of chondrocytes by targeting MyD88 in osteoarthritis

Molecular and Cellular Biochemistry, 2019
Osteoarthritis (OA) has been identified to be one of the most prevalent forms of joint disorders, marked with inflammatory immune response that may give rise to several complications including disability. Numbers of investigations have proven that microRNA play a key role in chondrogenesis regulation.
Jian Cao, Zhongxing Liu, Limin Zhang, Jinlong Li   +3 more
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LncRNA GATA2-AS1 suppresses esophageal squamous cell carcinoma progression via the mir-940/PTPN12 axis

Experimental Cell Research, 2022
Esophageal squamous cell carcinoma (ESCC) is a common malignant tumor worldwide. Long noncoding RNAs (lncRNAs) exhibit a regulatory role in the progression of ESCC. Our research was performed to investigate the potential molecular mechanism of lncRNA GATA2-AS1 in ESCC.The expression of GATA2-AS1 was identified by qRT-PCR.
Yunfeng, Niu, Yanli, Guo, Yan, Li, Supeng, Shen, Jia, Liang, Wei, Guo, Zhiming, Dong   +6 more
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INTERFERING HSA_CIRC_0001226 MITIGATES LPS-INDUCED BEAS-2B CELL INJURY BY REGULATING MIR-940/TGFBR2 PATHWAY

Shock, 2023
ABSTRACT Background: Sepsis-associated acute lung injury (SA-ALI) is a serious threat to human health. A growing body of evidence suggested that circular RNAs may be involved in ALI progression. The aim of this study was to investigate the effect and mechanism of circ_0001226 on lipopolysaccharide (LPS)–induced ...
Song, Mo, Qushen, Yi, Xuezhu, Bei, Yuan, Huang, Junhua, Lai   +4 more
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Depletion of circ_0128846 ameliorates interleukin-1β-induced human chondrocyte apoptosis and inflammation through the miR-940/PTPN12 pathway

International Immunopharmacology, 2022
Previous evidence has suggested that circular RNA (circRNA) is abnormally expressed in osteoarthritis (OA). However, the underlying mechanism of circRNA in OA progression remains unclear. The study aims to reveal the mechanism of circ_0128846 regulating OA.Human chondrocytes (C28/I2 cells) were treated with interleukin-1β (IL-1β) to mimic an OA cell ...
Guojian, Fu, Feng, Yin, Jianli, Zhao
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Circ_0006174 Upregulates IGF1R to Enhance Radioresistance and Tumorigenesis in Colorectal Cancer via miR-940 Suppression

Applied Biochemistry and Biotechnology
Colorectal cancer (CRC) is one of the most common malignancies all over the world. Increasing evidence has revealed that circular RNAs (circRNAs) are involved in the progression of CRC. In this study, we aimed to investigate the role and underlying mechanism of circ_0006174 in the development and radiosensitivity of CRC. Circ_0006174, microRNA-940 (miR-
Xuefeng, Zhang, Fang, Fang, Jiarui, Zhang, Sujuan, Zhang, Haonan, Li, Bingyao, Li, Yibo, Zhong, Peng, Zhen   +7 more
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Circ_0043582 promotes dental pulp cell injury via miR-940/TRAF3/NF-κB axis in pulpitis

Odontology
Pulpitis, a prevalent inflammatory dental disease, is characterized by persistent inflammation that severely compromises patients' quality of life. While circular RNAs (circRNAs) have been established as key regulators in numerous pathological conditions, their functional significance in pulpitis remains poorly understood.
Bin, Wu, Linlin, Jiang, Ying, Mu
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[Salvianolic acid A contributes to cartilage endplate cell restoration by regulating miR-940 and miR-576-5p].

Zhongguo gu shang = China journal of orthopaedics and traumatology, 2023
To investigate whether Salvianolic acid A (SAA) can restore cartilage endplate cell degeneration of intervertebral discs and to identify the mechanism via regulation of micro-RNA.Cartilage endplate cells were isolated from lumbar intervertebral disc surgical samples and were treated with serum containing a series of concentrations of SAA (2, 5, and 10 ?
Jia-Wen, Zhan, Shang-Quan, Wang, Ming, Chen, Kai, Sun, Jie, Yu, Ling-Hui, Li, Wu, Sun, Xin, Chen, Chu-Hao, Cai, Wei-Ye, Zhang, Tao, Han, Yu-Hui, Yin, Bin, Tang, Li-Guo, Zhu   +13 more
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MiR-940 may serve as a functional biomarker for detection of gastric cancer

2015
It was reported that miRNAs played significant roles in cancer development. In this study, miR-940 was identified as one of the most downregulated miRNAs in the plasma of patients with gastric cancer.
Chu, KM, Liu, X
openaire   +1 more source